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Table 30. Unknown Duration or Late Syphilis — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2018–2022

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Table 30. Unknown Duration or Late Syphilis — Reported Cases and Rates of Reported Cases by State/Territory and Region in Alphabetical Order, United States, 2018–2022
State/Territory Cases Rates per 100,000 Population
2018 2019 2020 2021 2022 2018 2019 2020 2021 2022
Alabama 354 461 489 699 974 7.2 9.4 9.7 13.9 19.2
Alaska 16 35 47 116 136 2.2 4.8 6.4 15.8 18.5
Arizona 1,243 1,444 1,637 2,691 3,545 17.3 19.8 22.9 37.0 48.2
Arkansas 287 414 484 836 1,293 9.5 13.7 16.1 27.6 42.5
California 9,609 11,817 10,572 13,530 16,022 24.3 29.9 26.7 34.5 41.1
Colorado 378 485 604 982 1,545 6.6 8.4 10.5 16.9 26.5
Connecticut 94 110 47 269 230 2.6 3.1 1.3 7.5 6.3
Delaware 63 55 53 76 138 6.5 5.6 5.4 7.6 13.6
District of Columbia 148 362 369 374 498 21.1 51.3 53.5 55.8 74.1
Florida 3,773 4,645 4,319 6,029 7,909 17.7 21.6 20.1 27.7 35.6
Georgia 1,773 2,144 2,038 2,930 3,264 16.9 20.2 19.0 27.1 29.9
Hawaii 27 34 113 259 242 1.9 2.4 7.8 18.0 16.8
Idaho 54 61 80 120 168 3.1 3.4 4.3 6.3 8.7
Illinois 1,570 1,760 1,845 2,421 2,927 12.3 13.9 14.4 19.1 23.3
Indiana 258 318 343 602 793 3.9 4.7 5.1 8.8 11.6
Iowa 112 126 143 197 251 3.5 4.0 4.5 6.2 7.8
Kansas 44 84 147 256 327 1.5 2.9 5.0 8.7 11.1
Kentucky 212 254 333 445 660 4.7 5.7 7.4 9.9 14.6
Louisiana 1,456 1,400 1,116 1,577 2,229 31.2 30.1 24.0 34.1 48.6
Maine 30 28 15 34 39 2.2 2.1 1.1 2.5 2.8
Maryland 913 888 888 NR 1,238 15.1 14.7 14.4 — 20.1
Massachusetts 133 600 485 675 829 1.9 8.7 6.9 9.7 11.9
Michigan 622 652 677 925 1,067 6.2 6.5 6.7 9.2 10.6
Minnesota 330 354 306 470 609 5.9 6.3 5.4 8.2 10.7
Mississippi 50 91 78 1,120 1,845 1.7 3.1 2.6 38.0 62.8
Missouri 544 706 916 1,611 1,859 8.9 11.5 14.9 26.1 30.1
Montana 34 47 33 98 205 3.2 4.4 3.0 8.9 18.3
Nebraska 63 109 113 207 329 3.3 5.6 5.8 10.5 16.7
Nevada 775 985 909 1,358 1,814 25.5 32.0 29.3 43.2 57.1
New Hampshire 31 37 37 33 65 2.3 2.7 2.7 2.4 4.7
New Jersey 406 612 807 1,299 1,382 4.6 6.9 8.7 14.0 14.9
New Mexico 337 552 744 1,086 1,365 16.1 26.3 35.1 51.3 64.6
New York 3,404 3,232 2,791 4,040 4,360 17.4 16.6 13.8 20.4 22.2
North Carolina 1,075 1,231 1,256 1,786 2,346 10.4 11.7 12.0 16.9 21.9
North Dakota 30 42 44 33 40 3.9 5.5 5.6 4.3 5.1
Ohio 667 718 785 1,250 1,725 5.7 6.1 6.7 10.6 14.7
Oklahoma 253 577 515 1,125 1,505 6.4 14.6 13.0 28.2 37.4
Oregon 299 416 369 556 716 7.1 9.9 8.7 13.1 16.9
Pennsylvania 416 622 671 1,014 1,389 3.2 4.9 5.2 7.8 10.7
Rhode Island 117 213 128 237 271 11.1 20.1 11.7 21.6 24.8
South Carolina 27 92 214 252 420 0.5 1.8 4.2 4.9 8.0
South Dakota 23 28 20 119 410 2.6 3.2 2.3 13.3 45.1
Tennessee 688 898 979 1,350 1,799 10.2 13.1 14.2 19.4 25.5
Texas 5,819 5,707 6,678 9,648 12,874 20.3 19.7 22.9 32.7 42.9
Utah 152 169 138 193 247 4.8 5.3 4.2 5.8 7.3
Vermont 0 2 9 2 0 0.0 0.3 1.4 0.3 0.0
Virginia 659 722 591 800 1,216 7.7 8.5 6.8 9.3 14.0
Washington 504 632 616 941 1,394 6.7 8.3 8.0 12.2 17.9
West Virginia 64 109 160 210 276 3.5 6.1 8.9 11.8 15.5
Wisconsin 193 195 232 502 750 3.3 3.3 3.9 8.5 12.7
Wyoming 8 21 14 17 36 1.4 3.6 2.4 2.9 6.2
US TOTAL 40,137 47,296 46,997 68,261 87,571 12.3 14.4 14.2 20.6 26.3
    Northeast 4,631 5,456 4,990 7,603 8,565 8.3 9.7 8.7 13.3 15.0
    Midwest 4,456 5,092 5,571 8,593 11,087 6.5 7.5 8.1 12.5 16.1
    South 17,614 20,050 20,560 30,118 40,484 14.1 16.0 16.3 23.7 31.5
    West 13,436 16,698 15,876 21,947 27,435 17.2 21.3 20.2 27.9 34.8
American Samoa 0 0 0 0 0 0.0 0.0 0.0 0.0 0.0
Commonwealth of the Northern Mariana Islands 1 1 0 2 1 1.9 1.9 0.0 3.9 1.9
Guam 9 21 16 9 15 5.4 12.5 9.5 5.3 8.9
Puerto Rico 138 155 216 391 515 4.2 4.9 6.6 12.0 16.0
US Virgin Islands NR NR 27 28 19 — — 25.4 26.4 18.0
TERRITORIES TOTAL 148 177 259 430 550 4.2 5.1 7.1 11.8 15.3
TOTAL 40,285 47,473 47,256 68,691 88,121 12.2 14.3 14.1 20.5 26.2
NR = No report.
NOTE: See Technical Notes for more information on syphilis case reporting and on interpreting case counts and rates in US territories. This report includes data from years that coincide with the COVID-19 pandemic, which introduced uncertainty and difficulty in interpreting case data. See Impact of COVID-19 on STIs for more information. Due to a network security incident in December 2021, the Maryland Department of Health could not finalize their 2021 STI case notification data. Although 2021 data from Maryland are included in national and regional case counts and rates displayed in this table, state-specific data have been suppressed.

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