Resistance or Elevated Minimum Inhibitory Concentration (MIC) Patterns of Neisseria gonorrhoeae Isolates to Antimicrobials, Gonococcal Isolate Surveillance Project (GISP), 2022

Combination of an upset figure and pie chart to display resistance or elevated minimum inhibitory concentration patterns of Neisseria gonorrhoeae isolates alone or in combination to selected antimicrobials during 2022.[PNG - 128 KB]

* Susceptible category includes isolates with penicillin (or Beta-lactamase negative), tetracycline, and ciprofloxacin MIC values that are not considered resistant (i.e., susceptible and intermediate resistant) based on Clinical & Laboratory Standards Institute criteria and isolates with ceftriaxone, cefixime, and azithromycin MIC values that are not considered elevated based on GISP “alert” values.

NOTE: Elevated MIC = Ceftriaxone: MIC ≥ 0.125 μg/mL; Cefixime: MIC ≥ 0.25 μg/mL; Azithromycin: MIC ≥ 2.0 μg/mL. Resistance = Tetracycline: MIC ≥ 2.0 μg/mL; Ciprofloxacin: MIC ≥ 1.0 μg/mL; Penicillin: MIC ≥ 2.0 μg/mL or Beta-lactamase positive. In the figure, a filled circle reflects resistance or elevated MIC to a specific antimicrobial; only antimicrobial combinations with non-zero percentages are shown.