Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings (2007)

Tdap Vaccine Recommendations [2018]

Update: Current recommendations can be found at CDC Tdap / Td ACIP Vaccine Recommendations.

Mumps [October 2017]

Update: The Healthcare Infection Control Practices Advisory Committee (HICPAC) voted to change the recommendation of isolation for persons with mumps from 9 days to 5 days based on this 2008 MMWR report.

Appendix A Updates [September 2018]

Changes: Updates and clarifications made to the table in Appendix A: Type and Duration of Precautions Recommended for Selected Infections and Conditions.

Edits and Changes [February 2017]

Changes to this guideline:

  • Minor content edits were made to improve clarity.
  • Spelling and punctuation were corrected.
  • Tables were formatted to be easily read by screen readers in compliance with the Americans with Disabilities Act (ADA).
  • Numbered or itemized items in paragraph format were converted to vertical numbered or bulleted lists in compliance with ADA.
  • Link text was changed to comply with ADA.
  • Live links were updated; dead links are indicated.
Ebola Virus Disease [August 2014]

Update: The recommendations in this guideline for Ebola has been superseded by these CDC documents:

See CDC’s Ebola Virus Disease website for current information on how Ebola virus is transmitted.

Ebola Virus Disease for Healthcare Workers [2014]

Update: Recommendations for healthcare workers can be found at Ebola for Clinicians.

Measles Update [April 2019]

This update aligns with and clarifies the ACIP 2011 Immunization of Healthcare Personnel Recommendations

Update: Susceptible healthcare personnel (HCP) should not enter room if immune care providers are available; regardless of presumptive evidence of immunity, HCP should use respiratory protection that is at least as protective as a fit-tested, NIOSH-certified N95 respirator upon entry into the patient’s room or care area. For exposed susceptibles, postexposure vaccine within 72 hours or immune globulin within 6 days when available [17, 1032, 1034].  Place exposed susceptible patients on Airborne Precautions and exclude susceptible healthcare personnel. See Immunization of Healthcare Personnel: Recommendations of the Advisory Committee on Immunization Practices (ACIP) pdf icon[PDF – 705 KB].

Environmental Control Recommendation Correction [April 2019]

Correction: For recommendation VI.C.1.c., the pressure differential changed from ≥ 12.5 to ≥ 2.5.

Varicella Post-exposure Prophylaxis Update [April 2019]

This update aligns with and clarifies the 2013 Updated Recommendations for use of VariZIG.

Update: For susceptible exposed persons for whom vaccine is contraindicated, provide varicella zoster immune globulin as soon as possible after exposure and within 10 days. See Updated Recommendations for Use of VariZIG — United States, 2013.

Gastroenteritis, Noroviruses Precaution Update [April 2019]

Update: The Type of Precaution for Gastroenteritis, Noroviruses, in Appendix A: Type and Duration of Precautions Recommended for Selected Infections and Conditions was updated from “Standard” to “Contact + Standard” to align with Guideline for the Prevention and Control of Norovirus Gastroenteritis Outbreaks in Healthcare Settings (2011).