What’s New?

March 24, 2022

New and Updated Chemicals Available

CDC’s National Report on Human Exposure to Environmental Chemicals (referred to as the Report) includes summary data for chemicals that have results available from NHANES starting with the 1999–2000 cycle. The Report is cumulative and includes all data tables previously published. This version of the Report:

• Now includes data from NHANES 2017–2018
• Adds five data tables for three chemicals reported for the first time or measured in a new matrix
• Updates 131 data tables for 97 chemicals measured in blood, serum, or urine specimens
• Incorporates 19 data tables for 18 chemicals previously published as “Early Releases”

Chemicals reported for the first time and those measured in a new matrix include:

Metals and Metalloids

• Urinary Chromium – these tables summarize data from NHANES 2017–2018 and complement blood chromium data, which have been updated and now include data from the 2015–2016 and 2017–2018 NHANES cycles. Among other uses, chromium data inform results of chromium biomonitoring in patients who have undergone joint replacement.
• Urinary Nickel – these tables summarize data from NHANES 2017–2018.

Volatile Organic Compounds

• Blood Methyl Isobutyl Ketone – this table summarizes data from NHANES 2011–2012. All percentile estimates were below the limit of detection.

Chemicals with updated data include:

Tobacco Alkaloids and Metabolites

• Serum Cotinine
• Serum trans-3’-Hydroxycotinine

Disinfection By-Products

• Blood Bromodichloromethane
• Blood Dibromochloromethane (Chlorodibromomethane)
• Blood Tribromomethane (Bromoform)
• Blood Trichloromethane (Chloroform)

Metals and Metalloids

• Urinary Antimony
• Urinary Total Arsenic
• Urinary Inorganic-related Arsenic Species
• Urinary Arsenic (V) acid
• Urinary Arsenobetaine
• Urinary Arsenocholine
• Urinary Arsenous (III) acid
• Urinary Dimethylarsinic acid
• Urinary Monomethylarsonic acid
• Urinary Trimethylarsine oxide
• Urinary Barium
• Blood Cadmium
• Urinary Cadmium
• Urinary Cesium
• Blood Cobalt
• Urinary Cobalt
• Blood Chromium
• Urinary Lead
• Blood Manganese
• Urinary Manganese
• Blood Total Mercury
• Blood Inorganic Mercury
• Blood Ethyl Mercury
• Blood Methyl Mercury
• Urinary Mercury
• Urinary Molybdenum
• Blood Selenium
• Urinary Strontium
• Urinary Thallium
• Urinary Tin
• Urinary Tungsten
• Urinary Uranium

Polycyclic Aromatic Hydrocarbon Metabolites

• Urinary 2-Hydroxyfluorene
• Urinary 3-Hydroxyfluorene
• Urinary 9-Hydroxyfluorene
• Urinary 1-Hydroxyphenanthrene
• Urinary 2-Hydroxyphenanthrene
• Urinary 3-Hydroxyphenanthrene
• Urinary 2- & 3-Hydroxyphenanthrene
• Urinary 4-Hydroxyphenanthrene
• Urinary 1-Hydroxypyrene
• Urinary 1-Hydroxynapthalene (1-Naphthol)
• Urinary 2-Hydroxynapthalene (2-Naphthol)

Volatile Organic Compounds (VOCs)

• Blood 1,1,1-Trichloroethane (Methyl chloroform)
• Blood 1,1,1,2-Tetrachloroethane
• Blood 1,1,2,2-Tetrachloroethane
• Blood 1,1,2-Trichloroethane
• Blood 1,2,3-Trichloropropane
• Blood 1,1-Dichloroethane
• Blood 1,1-Dichloroethene (Vinylidene chloride)
• Blood 1,2-Dibromoethane
• Blood 1,2-Dichlorobenzene (o-Dichlorobenzene)
• Blood 1,2-Dichloroethane (Ethylene dichloride)
• Blood trans-1,2-Dichloroethylene
• Blood 1,2-Dichloropropane
• Blood 1,3-Dichlorobenzene (m-Dichlorobenzene)
• Blood 1,4-Dichlorobenzene (p-Dichlorobenzene)
• Blood 1,4-Dioxane
• Blood 2,5-Dimethylfuran
• Blood Benzene
• Blood Benzonitrile
• Blood Chlorobenzene (Monochlorobenzene)
• Blood Chloroethane
• Blood Cyclohexane
• Blood Dibromomethane
• Blood Dichloromethane (Methylene chloride)
• Blood Diethyl Ether
• Blood Ethyl Acetate
• Blood Ethylbenzene
• Blood Furan
• Blood n-Heptane
• Blood Hexachloroethane
• Blood n-Hexane
• Blood Isobutyronitrile
• Blood Isopropylbenzene (Cumene)
• Blood Methyl tert-Butyl Ether (MTBE)
• Blood Methylcyclopentane
• Blood Nitrobenzene
• Blood Nitromethane
• Blood n-Octane
• Blood Tetrachloroethene (Perchloroethylene)
• Blood Tetrachloromethane (Carbon tetrachloride)
• Blood Tetrahydrofuran
• Blood Toluene
• Blood Trichloroethene (Trichloroethylene)
• Blood α,α,α-Trifluorotoluene
• Blood Vinyl Bromide
• Blood m-/p-Xylene
• Blood o-Xylene

Data tables previously published as “Early Releases” that have been incorporated into the Report:

Adducts of Hemoglobin

• Ethylene oxide

Metals and Metalloids

• Blood Lead

Per- and Polyfluorinated Substances (PFAS)

• Serum 9-Chlorohexadecafluoro-3-oxanonane-1-sulfonic acid
• Serum Adona (4,8-dioxa-3H-perfluorononanoate)
• Serum GenX (2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-propanoic acid (HFPO-DA))
• Serum Perfluorodecanoic acid (PFDA)
• Serum Perfluoroheptane sulfonic acid (PFHpS)
• Serum Perfluorohexane sulfonic acid (PFHxS)
• Serum Perfluorohexanoic acid (PFHxA)
• Serum Perfluorononanoic acid (PFNA)
• Serum Perfluorooctanoic acid (PFOA)
• Serum n-Perfluorooctanoic acid (n-PFOA)
• Serum branched Perfluorooctanoic acid (Sb-PFOA)
• Serum Perfluorooctane sulfonic acid (PFOS)
• Serum n-Perfluorooctane sulfonic acid (n-PFOS)
• Serum branched Perfluoromethylheptane sulfonic acid (Sm-PFOS)
• Serum 2-(N-Methyl-perfluorooctane sulfonamido) acetic acid (Me-PFOSA-AcOH or MeFOSAA)
• Serum Perfluoroundecanoic acid (PFUA or PFUnDA)