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Syphilis can have very serious consequences when left untreated.

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Fact Sheet

You should get tested regularly if you are pregnant, are a man who has sex with men, have HIV infection, and/or have partner(s) who have tested positive for syphilis.

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MSM Fact Sheet

83% of reported male primary and secondary (P&S) syphilis cases where sex of sex partner is known are among men who have sex with men (MSM).

	pregnant woman and her husband talking to doctor


Syphilis is easy to cure in its early stages. Pregnant women should be tested regularly for syphilis because infection with syphilis can cause serious problems in a baby.


Webinar: French Disease to Ipergay: Syphilis networks in the PrEP era by John Schneider, MD, MPH - January 26,2016

Ocular Syphilis — Eight Jurisdictions, United States, 2014–2015 MMWR November 4, 2016

Procaine Penicillin G Shortage (September 19, 2016)

Congenital Syphilis Is on the Rise? Reviewing Prevention Steps (July 19, 2016)

Changing the Story of Syphilis (May 24, 2016)

Bicillin-LA Shortage (updated May 23, 2016)

A Journey through Syphilis: How does Treponema pallidum cause such a complex disease? - STD Prevention Science Series Webinar, June 2, 2016, Recording Available

Medscape Commentary: Keep an Eye Out for Ocular Syphilis (added February 11, 2016)

Clinical Advisory: Ocular Syphilis in the United States (Updated January 7, 2016)

Increase in Incidence of Congenital Syphilis — United States, 2012–2014  MMWR November 13, 2015

Congenital Syphilis Fact Sheet (November 12. 2015)

Notes from the Field: A Cluster of Ocular Syphilis Cases — Seattle, Washington, and San Francisco, California, 2014–2015 MMWR October 16, 2015

2015 STD Treatment Guidelines - Syphilis - Includes diagnosis, treatment, prevention, and special considerations for syphilis infections. (June 4, 2015)

Guidance on Syphilis Testing in Latin America and the Caribbean - A guide by the Pan American Health Organization on improving uptake and quality of syphilis testing in different clinical settings (April 17. 2015)