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May 1994
 

Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)


Tellurium hexafluoride (as Te)

CAS number: 7783–80–4

NIOSH REL: 0.02 ppm (0.1 mg/m3) TWA

Current OSHA PEL: 0.02 ppm (0.2 mg/m3) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 0.02 ppm (0.10 mg/m3) TWA

Description of substance: Colorless gas with a repulsive odor.

LEL :. . Nonflammable Gas

Original (SCP) IDLH: 1 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the statements by ACGIH [1971] that "animals showed evidence of pulmonary edema (disturbed breathing) at the lowest exposure tested, 1 ppm for 4 hours; a 1-hour exposure at 1 ppm produced greatly accelerated respiration but no mortality" [Kimmerle 1960]. The IDLH has been conservatively set, but no other data on acute inhalation toxicity are available on which to base an IDLH. Exposure for 4 hours to higher concentrations (5, 10, 25, 50, and 100 ppm) invariably proved fatal to all exposed animals [Kimmerle 1960].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA:

Lethal concentration data:

 

SpeciesReferenceLC50

(ppm)

LCLo

(ppm)

TimeAdjusted 0.5-hr

LC (CF)

Derived value
Rat

Mouse

Rabbit

G. pig

Kimmerle 1960

Kimmerle 1960

Kimmerle 1960

Kimmerle 1960

-----

-----

-----

-----

5

5

5

5

4 hr

1 hr

4 hr

4 hr

10 ppm (2.0)

6.3 ppm (1.25)

10 ppm (2.0)

10 ppm (2.0)

1.0 ppm

0.6 ppm

1.0 ppm

1.0 ppm

Other animal data: It has been reported that animals showed evidence of pulmonary edema (disturbed breathing) at the lowest exposure tested, 1 ppm for 4 hours; a 1-hour exposure at 1 ppm produced greatly accelerated respiration but no mortality [Kimmerle 1960].

Human data: None relevant for use in determining the revised IDLH.

 

Revised IDLH: 1 ppm [Unchanged]

Basis for revised IDLH: Based on acute inhalation toxicity data in animals [Kimmerle 1960], the original IDLH for tellurium hexafluoride (1 ppm) is not being revised at this time.

REFERENCES:

1. ACGIH [1971]. Tellurium hexafluoride. In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 246.

2. Kimmerle G [1960]. Vergleichende untersuchungen der inhalationstoxicitat von schwefel-, selen- und tellurhexafluorid. Arch Toxikol 18:140-144 (in German).

 
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