Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Ammonium sulfamate

May 1994
Immediately Dangerous to Life or Health Concentrations (IDLH)

CAS number: 7773-06-0

NIOSH REL: 10 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA

Current OSHA PEL:15 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA

1989 OSHA PEL: 10 mg/m3 (total dust) TWA, 5 mg/m3 (respirable dust) TWA

1993-1994 ACGIH TLV 10 mg/m3 TWA

Description of substance: Colorless to white crystalline, odorless solid.

LEL: Noncombustible Solid

Original (SCP) IDLH: 5,000 mg/m3

Basis for original (SCP) IDLH: The chosen IDLH is based on the rat intraperitoneal LDLO of 800 mg/kg cited by NIOSH [1976] from Ambrose [1943]. This compound has a low toxicity.

Short-term exposure guidelines: None developed


Lethal dose data:

SpeciesReferenceRouteLD50(mg/kg)LDLo(mg/kg)Adjusted LDDerived Value
RatBall 1956oral2,000-----14,000 mg/m31,400 mg/m3
MouseGig Tr Prof Zabol 1963oral3,100-----21,700 mg/m32,170 mg/m3
RatLehman 1951oral3,900-----27,300 mg/m32,730 mg/m3
MouseLehman 1951oral5,760-----40,320 mg/m34,032 mg/m3

Human data: None relevant for use in determining the revised IDLH.

Revised IDLH: 1,500 mg/m3
Basis for revised IDLH: No inhalation toxicity data are available on which to base an IDLH for ammonium sulfamate. Therefore, the revised IDLH for ammonium sulfamate is 1,500 mg/m3 based on the acute oral toxicity data in animals [Ball 1956]. This may be a conservative value due to the lack of relevant acute toxicity data for workers.


  1. Ambrose AM [1943]. Studies of the physiological effects of sulfamic acid and ammonium sulfamate. J Ind Hyg Toxicol 25:26.
  2. Ball WL [1956]. Threshold limits for pesticides. AMA Arch Ind Health 14:178-185.
  3. Gig Tr Prof Zabol [1963]; 7(5):56-57 (in Russian).
  4. Lehman AJ [1951]. Chemicals in foods: a report to the Association of Food and Drug Officials on current developments. Part II. Pesticides. Q Bulletin Assoc Food Drug Off U.S. 15(4):122-125.
  5. NIOSH [1976]. WO61250. Sulfamic acid, monoammonium salt. In: Registry of Toxic Effects of Chemical Substances (RTECS) 1976 ed. Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Center for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 76-191, p. 1111.
Contact Us:
  • Page last reviewed: December 4, 2014
  • Page last updated: December 4, 2014 The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC-INFO