Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Cyclopentadiene

CAS number: 542–92–7

NIOSH REL: 75 ppm (200 mg/m3) TWA

Current OSHA PEL: 75 ppm (200 mg/m3) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 75 ppm (203 mg/m3) TWA

Description of Substance: Colorless liquid with an irritating, terpene-like odor.

LEL: . . Unknown

Original (SCP) IDLH: 2,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the statement by Deichmann and Gerarde [1969] that 4 of 6 rats died from a 4-hour exposure to 2,000 ppm [Smyth et al. 1954].

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA

Lethal concentration data:

 


Species

Reference
LC50

(ppm)

LCLo

(ppm)


Time
Adjusted 0.5-hr

LC (CF)

Derived

value

Rat

Mouse

Rat

Shashkina 1965

Shashkina 1965

Smyth et al. 1954

14,182

5,091

LC67: 2,000

-----

-----

-----

2 hr

2 hr

4 hr

22,691 ppm (1.6)

8,146 ppm (1.6)

4,000 ppm (2.0)

2,269 ppm

815 ppm

400 ppm


Human data: None relevant for use in determining the revised IDLH.

 

Revised IDLH: 750 ppm

Basis for revised IDLH: The revised IDLH for cyclopentadiene is 750 ppm based on acute inhalation toxicity data in animals [Shashkina 1965]. [Note: It was decided to use the 2-hour lethal concentration data in mice rather than the 4-hour lethal concentration data in rats so as not to magnify the conservatism already present in the correction factors.]


REFERENCES:

1. Deichmann WB, Gerarde HW [1969]. Table 48. Acute toxicity of hydrocarbons. In: Toxicology of drugs and chemicals. New York, NY: Academic Press, Inc., p. 734.

2. Shashkina LF [1965]. Materials for substantiation of maximum permissible concentration of cyclopentadiene and of its dimer -- dicyclopentadiene -- in the atmosphere of industrial premises. Gig Tr Prof Zabol 9(12):13-19 (in Russian).

3. Smyth HF Jr, Carpenter CP, Weil CS, Pozzani UC [1954]. Range-finding toxicity data: list V. AMA Arch Ind Hyg Occup Med 10:61-68.

 
Contact Us:
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO