Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home
May 1994

Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)


CAS number: 3689–24–5

NIOSH REL: 0.2 mg/m3 TWA [skin]

Current OSHA PEL: 0.2 mg/m3 TWA [skin]

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 0.2 mg/m3 TWA [skin]

Description of substance: Pale-yellow liquid with a garlic-like odor.

LEL :. . Unknown

Original (SCP) IDLH: 35 mg/m3

Basis for original (SCP) IDLH: The chosen IDLH is based on the rat oral LD50 of 5 mg/kg [Lehman 1951 cited by ACGIH 1971]. No other useful data are available on which to base the IDLH.

Short-term exposure guidelines: None developed


Lethal concentration data:


SpeciesReferenceLC50 LCLoTimeAdjusted 0.5-hr


Derived value
RatKimmerle & Klimmer 1974 38 mg/m3-----4 hr76 mg/m3 (2.0)7.6 mg/m3
MouseKimmerle & Klimmer 1974 40 mg/m3-----4 hr80 mg/m3 (2.0)8.0 mg/m3

Lethal dose data:






Adjusted LDDerived value
MouseKimmerle & Klimmer 1974 oral22-----154 mg/m315 mg/m3
RabbitKimmerle &Klimmer 1974 oral25-----175 mg/m318 mg/m3
DogKimmerle & Klimmer 1974 oral5-----35 mg/m33.5 mg/m3
RatLehman 1951oral5 -----35 mg/m3 3.5 mg/m3

Other animal data: It has been stated that TEDP is an organophosphate pesticide whose toxicity is similar to that of parathion [ACGIH 1991].

Human data: None relevant for use in determining the revised IDLH.


Revised IDLH: 10 mg/m3

Basis for revised IDLH: The revised IDLH for TEDP is 10 mg/m3 based on acute inhalation toxicity data in animals [Kimmerle and Klimmer 1974] and on an analogy with parathion [ACGIH 1991] which has a revised IDLH of 10 mg/m3.


1. ACGIH [1971]. TEDP (tetraethyl dithionopyrophosphate). In: Documentation of the threshold limit values for substances in workroom air. 3rd ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 244-245.

2. ACGIH [1991]. Sulfotep. In: Documentation of the threshold limit values and biological exposure indices. 6th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, pp. 1452-1454.

3. Kimmerle G, Klimmer OR [1974]. Acute and subchronic toxicity of sulfotep. Arch Toxicol 33:1-16.

4. Lehman AJ [1951]. Chemicals in foods: A report to the Association of Food and Drug Officials on current developments. Part II. Pesticides. Section II. Dermal Toxicity.  Q Bulletin Assoc Food Drug Off U.S. 16(1):3-9.

Contact Us: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO