Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home
May 1994

Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)


CAS number: 121–44–8

NIOSH REL: The 1989 OSHA PEL may not be protective to workers.

Current OSHA PEL: 25 ppm (100 mg/m3) TWA

1989 OSHA PEL: 10 ppm (40 mg/m3) TWA, 15 ppm (60 mg/m3) STEL

1993-1994 ACGIH TLV: 5 ppm (12 mg/m3) TWA, 15 ppm (36 mg/m3) STEL

Description of substance: Colorless liquid with a strong, ammonia-like odor.

LEL: . . 1.2% (10% LEL, 1,200 ppm)

Original (SCP) IDLH: 1,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on the UCC [1970] report that a 4-hour exposure to 1,000 ppm killed 1 of 6 rats.

Short-term exposure guidelines: None developed


Lethal concentration data:






TimeAdjusted 0.5-hr


Derived value
G. pig



Carpenter et al. 1948

Izmerov et al. 1982

Smyth et al. 1951

LC33: 1,000


LC17: 1,000




4 hr

2 hr

4 hr

2,000 ppm (2.0)

2,280 ppm (1.6)

2,000 ppm (2.0)

200 ppm

228 ppm

200 ppm

Other animal data: RD50 (mouse), 184 ppm [Nielsen and Yamagiwa 1989].

Human data: None relevant for use in determining the revised IDLH.


Revised IDLH: 200 ppm

Basis for revised IDLH: The revised IDLH for triethylamine is 200 ppm based on acute inhalation toxicity data in animals [Carpenter et al. 1948; Izmerov et al. 1982; Nielsen and Yamagiwa 1989; Smyth et al. 1951]. This may be a conservative value due to the lack of acute inhalation toxicity data for workers.


1. Carpenter CP, Smyth HF Jr, Shaffer CB [1948]. The acute toxicity of ethylene imine to small animals. J Ind Hyg Toxicol 30:2-6.

2. Izmerov NF, Sanotsky IV, Sidorov KK [1982]. Toxicometric parameters of industrial toxic chemicals under single exposure. Moscow, Russia: Centre of International Projects, GKNT, p. 115.

3. Nielsen GD, Yamagiwa M [1989]. Structure-activity relationships of airway irritating aliphatic amines. Receptor activation mechanisms and predicted industrial exposure limits. Chem Biol Interact 71(2-3):223-244.

4. Smyth HF Jr, Carpenter CP, Weil CS [1951]. Range-finding toxicity data: list IV. AMA Arch Ind Hyg Occup Med 4:119-122.

5. UCC [1970]. Toxicology studies: triethylamine. New York, NY: Union Carbide Corporation.

Contact Us: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Road Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO