Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)
CAS number: 105–46–4
NIOSH REL: 200 ppm (950 mg/m3) TWA
Current OSHA PEL: 200 ppm (950 mg/m3) TWA
1989 OSHA PEL: Same as current PEL
1993-1994 ACGIH TLV: 200 ppm (950 mg/m3) TWA
Description of Substance: Colorless liquid with a pleasant, fruity odor.
LEL: . . 1.7% (10% LEL, 1,700 ppm)
Original (SCP) IDLH: 10,000 ppm
Basis for original (SCP) IDLH: The chosen IDLH is based on an analogy with n-butyl acetate which has an IDLH of 10,000 ppm.
Short-term exposure guidelines: None developed
ACUTE TOXICITY DATA
Animal data: None relevant for use in determining the revised IDLH.
Human data: The vapor of sec-butyl acetate is reportedly less irritating than that of n-butyl acetate [Richmond and Pagnotto 1965].
|Revised IDLH: 1,700 ppm [LEL]
Basis for revised IDLH: Based on health considerations and an analogy to n-butyl acetate [Richmond and Pagnotto 1965], a value of about 2,500 ppm would have been appropriate for sec-butyl acetate. However, the revised IDLH for sec-Butyl acetate is 1,700 ppm based strictly on safety considerations (i.e., being 10% of the lower explosive limit of 1.7%).
1. Richmond M, Pagnotto LD . Comparative toxicity of selective
acetate esters. Unpublished data. [From: ACGIH . sec-Butyl
acetate. In: Documentation of the threshold limit values and biological
exposure indices. 6th ed. Cincinnati, OH: American Conference
of Governmental Industrial Hygienists, p. 166.]
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