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May 1994
 

Documentation for Immediately Dangerous To Life or Health Concentrations (IDLHs)


sec-Butyl acetate

CAS number: 105–46–4

NIOSH REL: 200 ppm (950 mg/m3) TWA

Current OSHA PEL: 200 ppm (950 mg/m3) TWA

1989 OSHA PEL: Same as current PEL

1993-1994 ACGIH TLV: 200 ppm (950 mg/m3) TWA

Description of Substance: Colorless liquid with a pleasant, fruity odor.

LEL: . . 1.7% (10% LEL, 1,700 ppm)

Original (SCP) IDLH: 10,000 ppm

Basis for original (SCP) IDLH: The chosen IDLH is based on an analogy with n-butyl acetate which has an IDLH of 10,000 ppm.

Short-term exposure guidelines: None developed

ACUTE TOXICITY DATA

Animal data: None relevant for use in determining the revised IDLH.

Human data: The vapor of sec-butyl acetate is reportedly less irritating than that of n-butyl acetate [Richmond and Pagnotto 1965].

 

Revised IDLH: 1,700 ppm [LEL]

Basis for revised IDLH: Based on health considerations and an analogy to n-butyl acetate [Richmond and Pagnotto 1965], a value of about 2,500 ppm would have been appropriate for sec-butyl acetate. However, the revised IDLH for sec-Butyl acetate is 1,700 ppm based strictly on safety considerations (i.e., being 10% of the lower explosive limit of 1.7%).


REFERENCE:

1. Richmond M, Pagnotto LD [1965]. Comparative toxicity of selective acetate esters. Unpublished data. [From: ACGIH [1991]. sec-Butyl acetate. In: Documentation of the threshold limit values and biological exposure indices. 6th ed. Cincinnati, OH: American Conference of Governmental Industrial Hygienists, p. 166.]

 
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