Interim Guidance for the Medical Screening of Workers Potentially Exposed to Engineered Nanoparticles

December 2007
NIOSH Docket Number 115

A public meeting was held on January 30, 2008, to discuss and obtain comments on the (12/14/07) draft Current Intelligence Bulletin: “Interim Guidance on Medical Screening of Workers Potentially Exposed to Engineered Nanoparticles.” Comments have been addressed and are listed at the end of this website. Also please note that the title of the 12/14/07 draft document has been changed and is reflected above

Final Document: Current Intelligence Bulletin 60: Interim Guidance for Medical Screening and Hazard Surveillance for Workers Potentially Exposed to Engineered Nanoparticles [PDF – 841K]

Pre-Meeting Information

72 FR 70598 – 12/12/07 [PDF – 798 KB]

NIOSH Current Intelligence Bulletin: Interim guidance for the medical screening of workers potentially exposed to engineered nanoparticles [PDF – 5,610 KB]

Meeting Information

Presentation by Trout (NIOSH) at the NIOSH Public Meeting; Cincinnati, OH – 1/30/08 [PDF – 2,120 KB]

List of attendees [PDF – 436 KB]

Agenda [PDF – 73 KB]

Post-Meeting Information

Submission to the docket from McDonald (Giner, Inc) – 1/3/08 [PDF – 128 KB]

Submission to the docket from Ali (Nanaphase Technologies Corporation) – 1/11/08 [PDF – 238 KB]

Submission to the docket from Muller (Navy and Marine Corps Public Health Center) – 1/14/08 [PDF – 136 KB]

Submission to the docket from Pineda (Health Science Associates) – 1/15/08 [PDF – 80 KB]

Submission to the docket from Bullock (Environmental Protection Agency) – 1/30/08 [PDF – 1,260 KB]

Submission to the docket from Slavin (American Nurses Association) – 1/30/08 [PDF – 179 KB]

Submission to the docket from DiLoreto (Synthetic Organic Chemical Manufacturers Association) – 2/14/08 [PDF – 400 KB]

Submission to the docket from Warheit (DuPont Haskell) – 2/15/08 [PDF – 453 KB]

Submission to the docket from Wambach (Department of Energy) – 2/15/08 [PDF – 124 KB]

Submission to the docket from Dozier (People for the Ethical Treatment of Animals) – 2/15/08 [PDF – 1,290 KB]

Submission to the docket from Ortlieb (United Steelworkers) – 2/15/08 [PDF – 1,830 KB]

Submission to the docket from Balbus (Environmental Defense Fund) – 2/19/08 [PDF – 267 KB]

Submission to the docket from Peer reviewer (1) – 2/28/08 [PDF – 257 KB]

Submission to the docket from Peer reviewer (2) – 4/15/08 [PDF – 1,310 KB]

Submission to the docket from Peer reviewer (1) – 4/23/08 [PDF – 363 KB]

Submission to the docket from Peer reviewer (3) – 9/25/08 [PDF – 585 KB]

NIOSH responses to public comments received on the 12/14/07 draft document [PDF – 2,050 KB]

NIOSH responses to peer reviewers’ comments received on the 12/14/07 draft document [PDF – 3,880 KB]

Peer Review

Title: Current Intelligence Bulletin 60: Interim Guidance for Medical Screening and Hazard Surveillance for Workers Potentially Exposed to Engineered Nanoparticles

Subject: The document proposes a framework for utilizing existing medical and hazard surveillance mechanisms to create occupational health surveillance programs for nanotechnology workers

Purpose: To help promote safe and healthy workplaces through recommendations

Timing of Review: November 2007 through February 15, 2008

Primary Disciplines or Expertise Needed for Review: Occupational Health and Medical Practitioners, Industrial Hygienists, Toxicologists, Safety Professionals

Type of Review: Individual

Number of Reviewers: 3

Reviewers Selected by: NIOSH

Public Nominations Requested for Reviewers: No

Opportunities for the Public to Comment: Yes

Peer Reviewers Provided with Public Comments Before Their Review: Yes

Peer Reviewers:

Ken Donaldson, PhD
Professor, ELEGI Colt Laboratory, Wilkie Laboratory MRC Centre for Inflammation Research University of Edinburgh Medical School
Recommended by: NIOSH

Michael Kosnett, MD, MPH
University of Colorado at Denver
Recommended by: NIOSH

Robert McCunney, PhD
Department of Biological Engineering, MIT
Areas of Expertise: Biological engineering
Recommended by: NIOSH

Charge to Peer Reviewers

  1. Do the data cited support the conclusions of the document?
  1. Are the conclusions appropriate in light of the current understanding of the toxicological data?
  2. Is medical surveillance appropriate at this time for workers with potential exposure to engineered nanoparticles; if so, what form(s) of medical surveillance are specific for such workers?
  3. What are the potential benefits, adverse impacts, and limitations of medical screening of workers potentially exposed to engineered nanoparticles?
  4. What are the potential benefits, adverse impacts, and limitations of establishing an exposure registry for workers exposed to engineered nanoparticles?
  5. What are the potential benefits, adverse impacts, and limitations of establishing an exposure registry for workers exposed to engineered nanoparticles?