Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

NCHHSTP Newsroom
Your Connection to the Latest HIV/AIDS, Hepatitis, STD and TB News at CDC

Media Summary

Provisional CDC Guidelines for the Use of and Safety Monitoring of Bedaquiline Fumarate (Sirturo) for the Treatment of Multidrug-Resistant Tuberculosis


CDC issues provisional guidance for health care providers on the use of bedaquiline fumarate, a new drug available to treat multidrug-resistant TB (MDR TB). There is a significant need for new drugs to treat TB, especially drug-resistant TB. Bedaquiline, which received accelerated FDA approval in December 2012, belongs to the first new class of TB drugs to be approved to treat this deadly disease in over 40 years. Following FDA approval, CDC began work on guidance to give additional direction to health care providers on the best use of the drug. Informed by a review of the science and extensive consultation with experts experienced in fighting TB across the country, CDC developed new guidelines that give health care providers another critically important tool in the fight against TB. Due to the potential for serious adverse events, bedaquiline is not recommended for all TB patients. Bedaquiline should be used for adults with laboratory-confirmed pulmonary MDR TB when no other treatment options exist, and may be used on a case-by-case basis for others. The guidance also includes recommendations for dosing, delivery, and monitoring for adverse events and clinical outcomes; the drug should always be used in combination with other anti-TB drugs, and close monitoring of patients for adverse reactions is critical. CDC will monitor the use of this drug and update guidance as additional information becomes available.

Media Contact:
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention
News Media Line - 404-639-8895
NCHHSTPMediaTeam@cdc.gov

###

U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

 
Media Inquiries:
HIV/AIDS, Hepatitis, STDs or TB
  • (404) 639-8895
    M-F 9am-5:30pm (ET)
  • Email

All Other Topics

Public Inquiries:
  • Centers for Disease Control and Prevention
    1600 Clifton Rd
    Atlanta, GA 30333
  • 800-CDC-INFO
    (800-232-4636)
    TTY: (888) 232-6348

  • Contact CDC–INFO

The NCHHSTP Atlas is an interactive tool that provides CDC an effective way to disseminate HIV, Viral Hepatitis, STD and TB data, while allowing users to observe trends and patterns by creating detailed reports, maps, and other graphics. Find out more! http://www.cdc.gov/nchhstp/atlas/


Prevention Through Health Care

CDC 24/7 – Saving Lives. Protecting People. Saving Money Through Prevention. Learn More About How CDC Works For You

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Road Atlanta, GA 30329-4027, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #