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Zinc stearate

RTECS #: ZH5200000

CAS #: 557-05-1


UPDATE: May 2008 MW: 632.43 MF: C36H70O4•Zn


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Coad
  2. Dermarone
  3. Dibasic zinc stearate
  4. Hydense
  5. Hytech
  6. Mathe
  7. Metallac
  8. Metasap 576
  9. Octadecanoic acid, zinc salt
  1. Petrac ZN - 41
  2. Stavinor ZN - E
  3. Stearates (ACGIH)
  4. Stearic acid, zinc salt
  5. Synpro stearate
  6. Talculin Z
  7. Zinc distearate
  8. Zinc octadecanoate
  9. Zinc stearate (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mammal (species unspecified)
lethal concentration : >1,241 mg/m3/4 hour N/R GTPZAB 36(4),17,1992
intraperitoneal
mouse
lethal dose (50 percent kill): 354 mg/kg N/R GTPZAB 36(4),17,1992
intratracheal
rat
lowest published lethal dose: 250 mg/kg Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion

Lung, Thorax, or Respiration: Other changes

Blood: Hemorrhage
BJIMAG 15,130,1958
oral
mouse
lethal dose (50 percent kill): >10 gm/kg N/R GTPZAB 36(4),17,1992
oral
rat
lethal dose (50 percent kill): >10 gm/kg N/R GTPZAB 36(4),17,1992


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - FINLAND time-weighted average 10 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 10 mg/m3, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 10 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 10 mg/m3;
short term exposure limit 20 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 10 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 10 mg/m3 (inspirable dust), JAN2002
Occupational Exposure Limit - RUSSIA short term exposure limit 4 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 5 mg/m3, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 3 mg/m3, DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m3 (inhalable), 2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 4 mg/m3;
short term exposure limit 20 mg/m3 (respirable), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ZINC STEARATE, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ZINC STEARATE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 77215;
Number of Industries 116;
Total Number of Facilities 10,040;
Number of Occupations 90;
Total Number of Employees Exposed 125,011
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 77215;
Number of Industries 163;
Total Number of Facilities 21,716;
Number of Occupations 110;
Total Number of Employees Exposed 382,620;
Total Number of Female Employees Exposed 136,358


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a flattening and sanding agent, as a drying lubricant and dusting agent
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

Used as a flattening and sanding agent, as a drying lubricant and dusting agent

NIOSH PROFILE (ZINC AND ITS COMPOUNDS), SRI, 2/77

FDA-over the counter drug

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