CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Pyrocatechol

RTECS #: UX1050000

CAS #: 120-80-9


UPDATE: May 2009 MW: 110.12 MF: C6H6O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1,2 - Benzenediol
  2. 1,2 - Dihydroxybenzene
  3. 2 - Hydroxyphenol
  4. Benzene, o - dihydroxy -
  5. C.I. 76500
  6. C.I. Oxidation Base 26
  7. Catechin (phenol)
  8. Catechol
  9. Catechol (ACGIH)
  10. Catechol (phenol)
  11. Durafur developer C
  12. Fouramine PCH
  13. Fourrine 68
  14. Katechol (Czech)
  1. NCI - C55856
  2. Oxyphenic acid
  3. Pelagol Grey C
  4. Phthalhydroquinone
  5. Pyrocatechin
  6. Pyrocatechine
  7. Pyrokatechin (Czech)
  8. o - Benzenediol
  9. o - Dihydroxybenzene
  10. o - Dioxybenzene
  11. o - Diphenol
  12. o - Hydroquinone
  13. o - Hydroxyphenol
  14. o - Phenylenediol


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis hamster embryo 3 Ámol/L MUREAV 373,113,1997
cytogenetic analysis hamster ovary 50 mg/L CALEDQ 14,251,1981
cytogenetic analysis hamster lung 60 Ámol/L/2 hour MUREAV 540,29,2003
DNA damage human lymphocyte 100 Ámol/L EMMUEG 26,305,1995
DNA damage mouse lymphocyte 500 Ámol/L MUREAV 203,155,1988
DNA damage other microorganisms 10 mmol/L MUREAV 368,235,1996
DNA damage rat liver 3 mmol/L CALEDQ 63,47,1992
DNA inhibition human HeLa cell 200 Ámol/L MUREAV 92,427,1982
DNA inhibition mouse lymphocyte 250 Ámol/L MOPMA3 28,560,1985
DNA repair Bacillus subtilis 500 mg/L ESKGA2 32,171,1986
unscheduled DNA synthesis hamster embryo 1 Ámol/L MUREAV 373,113,1997
unscheduled DNA synthesis oral
rat
1 gm/kg JJIND8 74,1283,1985
mutation in microorganisms Escherichia coli 2 mg/plate (-enzymatic activation step) MUREAV 467,41,2000
mutation in microorganisms Salmonella typhimurium 15 Ámol/plate (+enzymatic activation step) PAACA3 20,117,1979
mutation in microorganisms Salmonella typhimurium 4 Ág/plate (-enzymatic activation step) ABCHA6 45,327,1981
mutation in microorganisms Saccharomyes cerevisiae 599 mg/L/16 hour MUTAEX 20,105,2004
micronucleus test hamster lung 25 Ámol/L EVHPAZ 82,81,1989
micronucleus test hamster ovary 22.2 Ámol/L/24 hour (-enzymatic activation step) MUREAV 630,1,2007
micronucleus test oral
mouse
40 mg/kg MUREAV 208,61,1988
micronucleus test intraperitoneal
mouse
10 mg/kg MUREAV 341,29,1994
gene conversion and mitotic recombination Aspergillus nidulans 10 mmol/L MUTAEX 2,235,1987
gene conversion and mitotic recombination Saccharomyes cerevisiae 300 mg/L MUREAV 135,109,1984
mutation in mammalian somatic cells hamster embryo 10 Ámol/L MUREAV 373,113,1997
mutation in mammalian somatic cells mouse lymphocyte 2,500 Ág/L EMMUEG 11,523,1988
morphological transform hamster embryo 1 Ámol/L MUREAV 373,113,1997
morphological transform mouse other cell types 0.25 mg/L/12 day MUREAV 557,191,2004
other mutation test systems human lymphocyte 40 Ámol/L CNREA8 40,1189,1980
other mutation test systems rabbit bone marrow 2 mmol/L AJIMD8 7,485,1985
sister chromatid exchange hamster lung 12,500 nmol/L EVHPAZ 82,81,1989
sister chromatid exchange hamster embryo 10 Ámol/L MUREAV 373,113,1997
sister chromatid exchange human lymphocyte 40 Ámol/L CNREA8 40,1189,1980
sex chromosome loss and nondisjunction hamster embryo 30 Ámol/L MUREAV 373,113,1997


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
rat
lowest published toxic dose: 1 gm/kg (11 day pregnant) Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth) TJADAB 41,43,1990
subcutaneous
rat
lowest published toxic dose: 5 mg/kg (1 day prior to copulation) Reproductive: Maternal effects: Ovaries, fallopian tubes ENDOAO 57,466,1955


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lowest published toxic dose: 645 gm/kg/96 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Gastrointestinal: Tumors
JJCREP 81,207,1990
oral
mouse
lowest published toxic dose: 3,696 mg/kg/44 week- continuous Tumorigenic: Neoplastic by RTECS criteria

Tumorigenic: Facilitates action of known carcinogens

Gastrointestinal: Tumors
CALEDQ 139,167,1999
oral
rat
lowest published toxic dose: 437 gm/kg/2 year- continuous Tumorigenic: Carcinogenic by RTECS criteria

Gastrointestinal: Tumors
JJCREP 81,207,1990
oral
rat
toxic dose : 60,640 mg/kg/24 week- continuous Tumorigenic: Neoplastic by RTECS criteria

Gastrointestinal: Tumors
JJCREP 77,854,1986
oral
rat
toxic dose : 349 gm/kg/2 year- continuous Tumorigenic: Carcinogenic by RTECS criteria

Gastrointestinal: Tumors
FCTOD7 33,93,1995
oral
rat
lowest published toxic dose: 171 gm/kg/51 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Gastrointestinal: Tumors
JJCREP 85,17,1994
oral
rat
lowest published toxic dose: 7,854 mg/kg/34 week- intermittent Tumorigenic: Neoplastic by RTECS criteria

Gastrointestinal: Tumors
JTPAE7 29,180,2001
oral
rat
lowest published toxic dose: 102,648 mg/kg/104 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Gastrointestinal: Tumors
JTPAE7 29,180,2001


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
guinea pig
lowest published lethal dose: 150 mg/kg N/R HBTXAC 1,62,1955
intraperitoneal
guinea pig
lowest published lethal dose: 150 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
intraperitoneal
mouse
lethal dose (50 percent kill): 68 mg/kg N/R PHTOEH 64,247,1989
intraperitoneal
mouse
lethal dose (50 percent kill): 190 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
intravenous
cat
lowest published lethal dose: 100 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
intravenous
dog
lowest published lethal dose: 40 mg/kg N/R HBTXAC 1,62,1955
intravenous
dog
lowest published lethal dose: 40 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
oral
cat
lethal dose (50 percent kill): 100 mg/kg N/R IPSTB3 3,93,1976
oral
dog
lethal dose (50 percent kill): 130 mg/kg N/R IPSTB3 3,93,1976
oral
dog
lowest published lethal dose: 130 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
oral
guinea pig
lethal dose (50 percent kill): 210 mg/kg N/R AFREAW 3,197,1951
oral
mammal (species unspecified)
lethal dose (50 percent kill): 240 mg/kg Behavioral: Change in motor activity (specific assay)

Behavioral: Muscle contraction or spasticity

Lung, Thorax, or Respiration: Dyspnea
TPKVAL 15,136,1979
oral
mouse
lethal dose (50 percent kill): 260 mg/kg N/R AFREAW 3,197,1951
oral
mouse
lethal dose (50 percent kill): 100 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
oral
rat
lethal dose (50 percent kill): 260 mg/kg N/R AFREAW 3,197,1951
oral
rat
lethal dose (50 percent kill): 3,890 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
oral
rat
lowest published toxic dose: 48 mg/kg Peripheral Nerve and Sensation: Recording from peripheral motor nerve TPKVAL 15,136,1979
oral
rabbit
lowest published lethal dose: 200 mg/kg Behavioral: Altered sleep time (including change in righting reflex)

Blood: Luekopenia

Blood: Methemoglobinemia- Carboxhemoglobinemia
38MKAJ 2A,2585,1981
oral
rabbit
lowest published lethal dose: 1,000 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
parenteral
frog
lowest published lethal dose: 160 mg/kg Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Convulsions or effect on seizure threshold
AEPPAE 166,437,1932
subcutaneous
frog
lowest published lethal dose: 160 mg/kg N/R HBTXAC 1,62,1955
subcutaneous
guinea pig
lowest published lethal dose: 200 mg/kg N/R HBTXAC 1,62,1955
subcutaneous
guinea pig
lowest published lethal dose: 200 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
subcutaneous
mouse
lethal dose (50 percent kill): 247 mg/kg N/R INHEAO 5,143,1967
subcutaneous
mouse
lethal dose (50 percent kill): 247 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
subcutaneous
rat
lowest published lethal dose: 110 mg/kg N/R AIPTAK 176,193,1968
subcutaneous
rat
lowest published lethal dose: 200 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994
subcutaneous
rabbit
lowest published lethal dose: 225 mg/kg N/R JAFCAU 17,497,1969
skin
rabbit
lethal dose (50 percent kill): 800 mg/kg Skin: After topical application: Primary irritation

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
AIHAAP 37,596,1976
skin
rabbit
lethal dose (50 percent kill): 800 mg/kg Behavioral: Ataxia

Behavioral: Tetany

Lung, Thorax, or Respiration: Dyspnea
VCVGK* -,224,1994


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
mouse
lowest published toxic dose: 450 mg/kg/3 day- intermittent Blood: Changes in bone marrow not included in above

Blood: Changes in spleen
VCVGK* -,225,1994
intravenous
mouse
lowest published toxic dose: 450 mg/kg/3 day- intermittent Blood: Changes in bone marrow not included in above

Blood: Changes in spleen
VCVGK* -,225,1994
oral
chicken
lowest published toxic dose: 98 gm/kg/4 week- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field FEPRA7 29,568,1970
oral
rat
lowest published toxic dose: 15,470 mg/kg/34 week- intermittent Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) JTPAE7 29,180,2001
oral
rat
lowest published toxic dose: 2,226 mg/kg/7 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain JTPAE7 29,180,2001
oral
rat
lowest published toxic dose: 360 mg/kg/5 day- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases

Biochemical: Metabolism (intermediary): Lipids including transport
PHREP* 57,70,2005


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm (skin) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed animal carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 71,433,1999
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 15,155,1977
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 15,155,1977
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 71,433,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 71,433,1999
TOXICOLOGY REVIEW
MUREAV 566,99,2004
TOXICOLOGY REVIEW
MUREAV 567,227,2004
TOXICOLOGY REVIEW
MUREAV 567,109,2004
TOXICOLOGY REVIEW
MUREAV 567,151,2004
TOXICOLOGY REVIEW
MUREAV 627,10,2007
TOXICOLOGY REVIEW
MUREAV 584,1,2005
TOXICOLOGY REVIEW
BCLPT* 96,131,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 5 ppm (23 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 5 ppm (23 mg/m3), Skin, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 5 ppm (20 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 5 ppm (22 mg/m3), short term exposure limit 10 ppm (45 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 5 ppm (20 mg/m3), FEB2006
Occupational Exposure Limit - KOREA time-weighted average 5 ppm (20 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 5 ppm (20 mg/m3) (skin), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 20 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 5 ppm (23 mg/m3), skin, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 5 ppm (20 mg/m3), JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 0.5 mg/m3, Skin, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 5 ppm (20 mg/m3);
short term exposure limit 10 ppm (40 mg/m3), Skin, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 5 ppm (23 mg/m3), DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 5 ppm (23 mg/m3), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed animal carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed animal carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CATECHOL-air 10 hour time-weighted average 5 ppm (Sk) NIOSH* DHHS #95-121,1995
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M1763;
Number of Industries 4;
Total Number of Facilities 147;
Number of Occupations 6;
Total Number of Employees Exposed 642
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M1763;
Number of Industries 8;
Total Number of Facilities 700;
Number of Occupations 15;
Total Number of Employees Exposed 13,516;
Total Number of Female Employees Exposed 5,799


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a chemical intermediate, pharmaceutical and veterinary drug
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

38MKAJ "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2nd rev. ed. in 1985.
ABCHA6 Agricultural and Biological Chemistry. (Maruzen Co. Ltd., POB 5050, Tokyo International, Tokyo 100-31, Japan) V.25- 1961-
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC.
AFREAW Advances in Food Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-32, 1948-88.
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898-
AJIMD8 American Journal of Industrial Medicine. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980-
BCLPT* Basic & clinical pharmacology & toxicology (Copenhagen, Denmark : Nordic Pharmacological Society Oxford, UK : Distributed by Blackwell Munksgaard) V.94- 2004-
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917-
ESKGA2 Eisei Kagaku. Hygienic Chemistry. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1953-
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963-
IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK)
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
JJCREP Japanese Journal of Cancer Research. (Elsevier Science Pub. BV, POB 211, 1000 AE Amsterdam, Netherlands) V.76- 1985-
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ.
JTPAE7 Journal of Toxicologic Pathology. (Nihon Dokusei Byori Gakkai, editor, 3-25-8 Nishi- shinbashi, Minato-ku, Tokyo 105, Japan) V.1- 1988
MOPMA3 Molecular Pharmacology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1965-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954-
PHREP*
PHTOEH Pharmacology and Toxicology (Copenhagen). (Munksgaard International Pub., POB 2148, DK-1016 Copenhagen K, Denmark) V.60- 1987-
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.

Used as a chemical intermediate, pharmaceutical and veterinary drug

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data

Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us