CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Propionic acid, 2,2 - dichloro -

RTECS #: UF0690000

CAS #: 75-99-0


UPDATE: May 2009 MW: 142.97 MF: C3H4Cl2O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 2,2 - Dichloropropanoic acid
  2. 2,2 - Dichloropropionic acid
  3. 2,2 - Dichloropropionic acid (ACGIH)
  4. Alatex
  5. BH dalapon
  6. Basinex
  7. Basinex P
  8. Crisapon
  9. Dalapon
  1. Dalapon 85
  2. Dalascam
  3. Kyselina 2,2 - dichlorpropionova (Czech)
  4. Propanoic acid, 2,2 - dichloro - (9CI)
  5. Proprop
  6. S 1315
  7. S 95 (herbicide)
  8. Tripon
  9. alpha,alpha - Dichloropropionic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
mutation in microorganisms other microorganisms 500 ppm (-enzymatic activation step) IJEBA6 11,114,1973


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
chicken
lethal dose (50 percent kill): >5 gm/kg N/R ENTOX* -,723,2005
skin
rat
lethal dose (50 percent kill): >5 gm/kg N/R FAATDF 7,299,1986


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 mg/m3 (inhalable) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
RREVAH 53,109,1974
TOXICOLOGY REVIEW
DTTIAF 80,485,1973
TOXICOLOGY REVIEW
ENTOX* -,723,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,108,1998
Occupational Exposure Limit - AUSTRALIA time-weighted average 1 ppm (5.8 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 5 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 1 ppm (6 mg/m3), OCT 2002
Occupational Exposure Limit - FRANCE VME 1 ppm (6 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 5.9 mg/m3 (1 mL/m3), 2005
Occupational Exposure Limit - KOREA time-weighted average 1 ppm (6 mg/m3), 2006
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 6 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 1 ppm (5.8 mg/m3), JAN2002
Occupational Exposure Limit - RUSSIA short term exposure limit 10 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 1 ppm (6 mg/m3),KZG- week 1 ppm (6 mg/m3), DEC2006


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 2,2-DICHLOROPROPIONIC ACID-air 10 hour time-weighted average 1 ppm NIOSH* DHHS #95-121,1995
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83057;
Number of Industries 1;
Total Number of Facilities 3;
Number of Occupations 3;
Total Number of Employees Exposed 51


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used against quackgrass, bermudagrass, johnsongrass, cattails, rushes, etc.
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970.
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-

Used against quackgrass, bermudagrass, johnsongrass, cattails, rushes, etc.

RTECS Compound Description:
   Agricultural Chemical
   Mutagen

Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us