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Registry of Toxic Effects of Chemical Substances (RTECS)

Isopropyl alcohol

RTECS #

NT8050000

CAS #

67-63-0; 8013-70-5

Updated

December 2013

Molecular Weight

60.11

Molecular Formula

C3H8O

Synonyms

1-Methylethanol
1-Methylethyl alcohol
2-Hydroxypropane
2-Propanol
2-Propyl alcohol
Alcojel
Alcool isopropilico (Italian)
Alcool isopropylique (French)
Alcosolve
Avantin
Avantine
Combi-schutz
Dimethylcarbinol
Hartosol
Imsol A
i-Propanol (German)
i-Propylalkohol (German)
IPS 1 (alcohol)
Isohol
Isopropanol
Isopropyl alcohol (ACGIH:OSHA)
Iso-propylalkohol (German)
Lutosol
n-Propan-2-ol
Petrohol
PRO
sec-Propyl alcohol
Spectrar
Sterisol hand disinfectant
Takineocol
Virahol

Skin and Eye Irritation and References

Route/OrganismDoseEffectReference
eye /rabbit 100 mg severeAJOPAA 29,1363,1946
eye /rabbit 10 mg moderateTXAPA9 55,501,1980
eye /rabbit 100 mg/24H moderate85JCAE -,191,1986
skin /rabbit 500 mg mildNTIS** AD-A106-944

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
Cytogenetic Analysisinhalation/rat1030 µg/m3/16W- intermittentGTPZAB 25(7),33,1981
sex chromosome loss and nondisjunctioninhalation/Drosophila melanogaster25 pphMUREAV 726,215,2011
specific locus testinhalation/Drosophila melanogaster50 pphMUREAV 726,215,2011

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
inhalation/rat 3500 ppm/7H (1-19D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)FCTOD7 26,247,1988
inhalation/rat 10000 ppm/7H (1-19D pregnant)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetal death
FCTOD7 26,247,1988
inhalation/rat 7000 ppm/7H (1-19D pregnant)Reproductive: Specific developmental abnormalities: Musculoskeletal systemFCTOD7 26,247,1988
oral/rabbit 6240 mg/kg (6-18D pregnant)Reproductive: Other effects on femaleFAATDF 22,139,1994
oral/rat 3276 mg/kg (182D prior to copulation)Reproductive: Other developmental abnormalities

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
VCVGK* -,98,1994
oral/rat 2278 mg/kg (6-16D pregnant)Reproductive: Other effects on female

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)
BDERB* 83,459,2008
oral/rat 11340 mg/kg (45D prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disordersGISAAA 43(1),8,1978
oral/rat 5040 mg/kg (1-20D pregnant)Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)GISAAA 43(1),8,1978
oral/rat 8 gm/kg (6-15D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)RTOPDW 23,183,1996
oral/rat 32400 µg/kg (26W prior to copulation)Reproductive: Effects on embryo or fetus: Fetal deathGISAAA 43(1),8,1978
oral/rat 3500 gm/kg (multigeneration)Reproductive: Effects on fertility: Mating performance (e.g., # sperm positive females per # females mated; # copulations per # estrus cycles)TOXID9 13,75,1993

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 394389 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 44999 µmol/L/21HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (50 percent kill): 344989 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
In Vitro/Chicken, neurons Inhibitor Concentration (10 percent kill): 68128 µmol/L/20HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 7,653,1993
In Vitro/Hamster, lung fibroblast Inhibitor Concentration (50 percent kill): 84 mmol/L/60HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,511,1993
In Vitro/Hamster, lung fibroblast Inhibitor Concentration (10 percent kill): 11.5 mmol/L/60HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,511,1993
In Vitro/Hamster, lung fibroblast Inhibitor Concentration Low: >104 mmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 1,3,1987
In Vitro/Human, HeLa cell Inhibitor Concentration (50 percent kill): 700.5 mmol/L/60HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,511,1993
In Vitro/Human, HeLa cell Inhibitor Concentration (10 percent kill): 6.5 mmol/L/60HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,511,1993
In Vitro/Human, liver Inhibitor Concentration (50 percent kill): 49 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 6,47,1992
In Vitro/Human, liver tumor Inhibitor Concentration (50 percent kill): 256 mmol/L/24HIn Vitro Toxicity Studies: Cell protein synthesisTIVIEQ 3,189,1989
In Vitro/Human, liver tumor Inhibitor Concentration Low: >91 mmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 1,3,1987
In Vitro/Human, neuroblastoma Inhibitor Concentration (20 percent kill): 12 mmol/L/30MIn Vitro Toxicity Studies: Other assaysTXAPA9 245,191,2010
In Vitro/Human, skin Inhibitor Concentration (50 percent kill): 22800 mg/L/48HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 6,367,1992
In Vitro/Human, skin Inhibitor Concentration (50 percent kill): 109000 mg/L/1MIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 6,367,1992
In Vitro/Mouse, fibroblast Inhibitor Concentration Low: >104 mmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 1,3,1987
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 414 mmol/L/48HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 184 mmol/L/72HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 523 mmol/L/48HIn Vitro Toxicity Studies: Cell protein synthesisTIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 300 mmol/L/72HIn Vitro Toxicity Studies: Cell protein synthesisTIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 400 mmol/L/48HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 326 mmol/L/72HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 5,449,1991
In Vitro/Mouse, fibroblast Inhibitor Concentration (50 percent kill): 48 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 6,47,1992
In Vitro/Mouse, liver Inhibitor Concentration (50 percent kill): 520 mmol/L/2HBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Transaminases
TIVIEQ 4,783,1990
In Vitro/Mouse, macrophage Inhibitor Concentration Low: >104 mmol/L/24HIn Vitro Toxicity Studies: Cell viability (lysosomal damage): neutral red assay etc.TIVIEQ 1,3,1987
In Vitro/Non-mammalian species, fibroblast Inhibitor Concentration (50 percent kill): 568 mmol/L/24HIn Vitro Toxicity Studies: Cell countingTIVIEQ 7,537,1993
In Vitro/Rat, liver Inhibitor Concentration (50 percent kill): 41 µmol/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 6,47,1992
In Vitro/Rat, lung Inhibitor Concentration (50 percent kill): 10.9 gm/L/24HIn Vitro Toxicity Studies: Cell membrane integrity (prelabeled cells): release of radioactive isotopes ([51Cr], [3H]-thymidine, [3H]-proline, [35S]- or [75Se]-methionine, 5-[125I]-2-deoxy-uridine) or fluorescent dyes (bis-carboxyethyl-carboxyfluorescein (BCECF) or calcein-AM)TIVIEQ 7,111,1993
In Vitro/Rat, lung Inhibitor Concentration (50 percent kill): 8.1 gm/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,111,1993
In Vitro/Rat, lung Inhibitor Concentration (10 percent kill): 6.03 gm/L/24HIn Vitro Toxicity Studies: Cell membrane integrity (prelabeled cells): release of radioactive isotopes ([51Cr], [3H]-thymidine, [3H]-proline, [35S]- or [75Se]-methionine, 5-[125I]-2-deoxy-uridine) or fluorescent dyes (bis-carboxyethyl-carboxyfluorescein (BCECF) or calcein-AM)TIVIEQ 7,111,1993
In Vitro/Rat, lung Inhibitor Concentration (75 percent kill): 15.9 gm/L/24HIn Vitro Toxicity Studies: Cell membrane integrity (prelabeled cells): release of radioactive isotopes ([51Cr], [3H]-thymidine, [3H]-proline, [35S]- or [75Se]-methionine, 5-[125I]-2-deoxy-uridine) or fluorescent dyes (bis-carboxyethyl-carboxyfluorescein (BCECF) or calcein-AM)TIVIEQ 7,111,1993
In Vitro/Rat, lung Inhibitor Concentration (10 percent kill): 5.6 gm/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,111,1993
In Vitro/Rat, lung Inhibitor Concentration (75 percent kill): 10.2 gm/L/24HIn Vitro Toxicity Studies: Cell viability (mitochondrial reductase assays): MTT, XTT, MTS, WSTs assays etc.TIVIEQ 7,111,1993
inhalation/guinea pig lowest published toxic concentration: 980 mg/m3/24HEar: Tumors

Behavioral: General anesthetic

Lung, Thorax, or Respiration: Other changes
VCVGK* -,97,1984
inhalation/human lowest published toxic concentration: 150 ppm/2HBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymesTOXID9 60,428,2001
inhalation/human lowest published toxic concentration: 35 ppm/4HCardiac: Pulse rate decreased with fall in BP

Lung, Thorax, or Respiration: Other changes
NRTXDN 24,179,2003
inhalation/mouse lowest published toxic concentration: 3000 ppm/6MLung, Thorax, or Respiration: Respiratory depressionTOLED5 9,137,1981
inhalation/mouse lethal concentration (50 percent kill): 53000 mg/m3Behavioral: General anesthetic

Lung, Thorax, or Respiration: Other changes
VCVGK* -,97,1984
inhalation/mouse Lowest published lethal concentration: 12800 ppm/3HIAEC** 17JUN1974
inhalation/rat lethal concentration (50 percent kill): 72600 mg/m3Behavioral: General anesthetic

Lung, Thorax, or Respiration: Other changes
VCVGK* -,97,1984
inhalation/rat lethal concentration (50 percent kill): 16000 ppm/8HNPIRI* 1,100,1974
intraperitoneal/guinea pig lethal dose (50 percent kill): 2560 mg/kgEVHPAZ 61,321,1985
intraperitoneal/hamster lethal dose (50 percent kill): 3444 mg/kgEVHPAZ 61,321,1985
intraperitoneal/mouse lethal dose (50 percent kill): 4477 mg/kgEVHPAZ 61,321,1985
intraperitoneal/rabbit lethal dose (50 percent kill): 667 mg/kgEVHPAZ 61,321,1985
intraperitoneal/rat lowest published toxic dose: 800 mg/kgBehavioral: AtaxiaVCVGK* -,97,1984
intraperitoneal/rat lethal dose (50 percent kill): 2735 mg/kgEVHPAZ 61,321,1985
intravenous/cat lowest published lethal dose: 1963 mg/kgHBTXAC 1,172,1955
intravenous/Dog lowest published lethal dose: 1024 mg/kgJLCMAK 29,561,1944
intravenous/mouse lethal dose (50 percent kill): 1509 mg/kgENTOX* ,706,2005
intravenous/rabbit lethal dose (50 percent kill): 1184 mg/kgEVHPAZ 61,321,1985
intravenous/rat lethal dose (50 percent kill): 1088 mg/kgEVHPAZ 61,321,1985
oral/cat lowest published lethal dose: 6 mL/kgAIPTAK 26,285,1921
oral/Dog lowest published lethal dose: 1537 mg/kgGastrointestinal: Nausea or vomitingJLCMAK 29,561,1944
oral/human lowest published toxic dose: 286 mg/kgCardiac: Arrythmias (indlucing changes in conduction)

Behavioral: Coma

Kidney, Ureter, and Bladder: Other changes
VCVGK* -,97,1984
oral/human lowest published lethal dose: 571 mL/kgVCVGK* -,97,1984
oral/human lowest published toxic dose: 223 mg/kgBehavioral: Hallucinations, distorted perceptions

Cardiac: Pulse rate decreased with fall in BP

Vascular: BP lowering not characterized in autonomic section
JLCMAK 12,326,1927
oral/human lowest published lethal dose: 3570 mg/kgBehavioral: Coma

Lung, Thorax, or Respiration: Respiratory depression

Gastrointestinal: Nausea or vomiting
34ZIAG -,339,1969
oral/infant lowest published toxic dose: 13 gm/kgBehavioral: Somnolence (general depressed activity)

Behavioral: Irritability

Gastrointestinal: Nausea or vomiting
AJEMEN 10,542,1992
oral/man lowest published lethal dose: 5272 mg/kgBehavioral: Coma

Vascular: BP lowering not characterized in autonomic section

Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion
AJCPAI 38,144,1962
oral/man lowest published toxic dose: 14432 mg/kgBehavioral: Coma

Vascular: BP lowering not characterized in autonomic section

Lung, Thorax, or Respiration: Dyspnea
NEJMAG 277,699,1967
oral/mouse lethal dose (50 percent kill): 3600 mg/kgBehavioral: Altered sleep time (including change in righting reflex)

Behavioral: Somnolence (general depressed activity)
GISAAA 43(1),8,1978
oral/mouse lethal dose (50 percent kill): 3600 mg/kgBehavioral: General anestheticVCVGK* -,97,1984
oral/rabbit lethal dose (50 percent kill): 6410 mg/kgFAONAU 48A,114,1970
oral/rat lethal dose (50 percent kill): 5000 mg/kgBehavioral: General anestheticVCVGK* -,97,1984
oral/rat lethal dose (50 percent kill): 5045 mg/kgBehavioral: Altered sleep time (including change in righting reflex)

Behavioral: Somnolence (general depressed activity)
GISAAA 43(1),8,1978
parenteral/frog lowest published lethal dose: 20 gm/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Somnolence (general depressed activity)
AIPTAK 50,296,1935
skin/rabbit lethal dose (50 percent kill): 12800 mg/kgNPIRI* 1,100,1974
subcutaneous/mammal (species unspecified) lowest published lethal dose: 6 gm/kgPeripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: General anesthetic

Lung, Thorax, or Respiration: Other changes
ATXKA8 16,84,1956
subcutaneous/mouse lowest published lethal dose: 6 gm/kgHBTXAC 1,172,1955
unreported route/human lowest published lethal dose: 2 mL/kgJJTOEX 12,341,1999
unreported route/infant lowest published toxic dose: 1375 mg/kgEye: Other eye effects

Behavioral: Somnolence (general depressed activity)

Behavioral: Hallucinations, distorted perceptions
PECAE5 9,146,1993
unreported route/man lowest published lethal dose: 2770 mg/kg85DCAI 2,73,1970

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
inhalation/mouse lowest published toxic concentration: 10000 ppm/6H/11D- intermittentBehavioral: General anesthetic

Behavioral: Ataxia

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NTIS** OTS0522901-2
inhalation/mouse lowest published toxic concentration: 5000 ppm/6H/13W- intermittentBehavioral: Somnolence (general depressed activity)

Liver: Changes in liver weight

Blood: Pigmented or nucleated red blood cells
NTIS** OTS0529356
inhalation/mouse lowest published toxic concentration: 5000 ppm/6H/13W- intermittentBehavioral: General anesthetic

Behavioral: Ataxia

Liver: Changes in liver weight
RTOPDW 23,183,1996
inhalation/mouse lowest published toxic concentration: 5000 ppm/6H/78W- intermittentBrain and Coverings: Changes in brain weight

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
RTOPDW 23,183,1996
inhalation/rat lowest published toxic concentration: 4900 mg/m3/6H/2W- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effectsVCVGK* -,97,1994
inhalation/rat lowest published toxic concentration: 1000 mg/m3/6H/4W- intermittentEye: Optic nerve neuropathyVCVGK* -,97,1994
inhalation/rat lowest published toxic concentration: 100 mg/m3/4H/17W- intermittentKidney, Ureter, and Bladder: Other changes in urine composition

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: True cholinesterase
GTPZAB 29(7),60,1985
inhalation/rat lowest published toxic concentration: 8000 ppm/8H/20W- intermittentPeripheral Nerve and Sensation: Sensory change involving peripheral nerve

Peripheral Nerve and Sensation: Recording from peripheral motor nerve
ENVRAL 62,148,1993
inhalation/rat lowest published toxic concentration: 5000 ppm/6H/90D- intermittentBehavioral: Change in motor activity (specific assay)TOXID9 14,97,1994
inhalation/rat lowest published toxic concentration: 2500 ppm/6H/2Y- intermittentLiver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes in urine composition

Kidney, Ureter, and Bladder: Changes in bladder weight
TOXID9 15,183,1995
inhalation/rat lowest published toxic concentration: 500 mg/m3/4H/122D- intermittentLiver: Multiple effects

Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVGK* -,98,1994
inhalation/rat lowest published toxic concentration: 20 mg/m3/24H/90D- continuousBrain and Coverings: Other degenerative changes

Lung, Thorax, or Respiration: Other changes

Liver: Multiple effects
VCVGK* -,98,1994
oral/rat lowest published toxic dose: 2196 mg/kg/122D- intermittentEndocrine: Effect on menstrual cycleVCVGK* -,98,1994
oral/rat lowest published toxic dose: 2196 mg/kg/122D- intermittentReproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)VCVGK* -,98,1994
oral/rat lowest published toxic dose: 7 mL/kg/7D- intermittentLiver: Other changes

Biochemical: Effect on specific coenzyme: B vitamins including folate
JDGRAX 10(1-2),25,1978
oral/rat lowest published toxic dose: 11340 mg/kg/45D- intermittentEndocrine: Effect on menstrual cycleVCVGK* -,98,1994

Reviews

OrganizationStandardReference
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-time-weighted average 200 ppm;short term exposure limit 400 ppmDTLVS* TLV/BEI,2013
American Conference of Governmental Industrial Hygienists (ACGIH)Threshold Limit Value-Not classifiable as a human carcinogenDTLVS* TLV/BEI,2013
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 15,223,1977
International Agency for Research on Cancer (IARC)Cancer Review:Animal Inadequate EvidenceIMEMDT 71,1027,1999
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMSUDL 7,229,1987
International Agency for Research on Cancer (IARC)Cancer Review:Human Inadequate EvidenceIMEMDT 71,1027,1999
International Agency for Research on Cancer (IARC)Cancer Review:Group 3IMEMDT 71,1027,1999
TOXICOLOGY REVIEWJIHTAB 20,428,1938
TOXICOLOGY REVIEWCLCHAU 19,361,1973
TOXICOLOGY REVIEWFNSCA6 2,67,1973
TOXICOLOGY REVIEWTOLED5 140-141,239,2003
TOXICOLOGY REVIEWTOLED5 140-141,261,2003
TOXICOLOGY REVIEWAJINC* 34,627,2006
TOXICOLOGY REVIEWAJEMEN 22,404,2004
TOXICOLOGY REVIEWHUTOX* -,577,1996
TOXICOLOGY REVIEWHUTOX* -,623,1996
TOXICOLOGY REVIEWFCTOD7 47,1287,2009
TOXICOLOGY REVIEWNBREV* 5,1,1981
TOXICOLOGY REVIEWNTAPM* -,727,1995
TOXICOLOGY REVIEWREPTED 32,142,2011

Standards and Regulations

OrganizationStandardReference
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATIONFEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDESRED CompletedRBREV* -,290,1998
Mine Safety and Health Administration (MSHA) STANDARD-airtime-weighted average 400 ppm (980 mg/m3)DTLVS* 3,141,1971
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN check ACGIH TLV;
Occupational Exposure Limit IN SINGAPORE, VIETNAM check ACGIH TLV
Occupational Exposure Limit-AUSTRALIAtime-weighted average 400 ppm (983 mg/m3), short term exposure limit 500 ppm (1230 mg/m3), JUL2008
Occupational Exposure Limit-AUSTRIAMAK-TMW 200 ppm (500 mg/m3);KZW 800 ppm (2000 mg/m3), 2007
Occupational Exposure Limit-BELGIUMtime-weighted average 400 ppm (997 mg/m3), MAR2002
Occupational Exposure Limit-BELGIUMshort term exposure limit 500 ppm (1248 mg/m3), MAR2002
Occupational Exposure Limit-DENMARKtime-weighted average 200 ppm (490 mg/m3), MAY2011
Occupational Exposure Limit-FRANCEVLE 400 ppm (980 mg/m3), FEB2006
Occupational Exposure Limit-GERMANYMAK 200 ppm (500 mg/m3), 2011
Occupational Exposure Limit-HUNGARYtime-weighted average 500 mg/m3, short term exposure limit 2000 mg/m3, Skin, SEP2000
Occupational Exposure Limit-ICELANDtime-weighted average 200 ppm (490 mg/m3), skin, NOV2011
Occupational Exposure Limit-JAPANceiling concentration 400 ppm (980 mg/m3), MAY2012
Occupational Exposure Limit-KOREAtime-weighted average 400 ppm (980 mg/m3), short term exposure limit 500 ppm (1225 mg/m3), 2006
Occupational Exposure Limit-MEXICOtime-weighted average 400 ppm (980 mg/m3);short term exposure limit 500 ppm (1225 mg/m3), 2004
Occupational Exposure Limit-NEW ZEALANDtime-weighted average 400 ppm (983 mg/m3); short term exposure limit 500 ppm (1230 mg/m3), JAN2002
Occupational Exposure Limit-PERUtime-weighted average 200 ppm (491 mg/m3); short term exposure limit 400 ppm (983 mg/m3), JUL2005
Occupational Exposure Limit-POLANDMAC(time-weighted average) 900 mg/m3, MAC(short term exposure limit) 1200 mg/m3, JAN1999
Occupational Exposure Limit-RUSSIAtime-weighted average 10 mg/m3, short term exposure limit 50 mg/m3, JUN2003
Occupational Exposure Limit-SWEDENtime-weighted average 150 ppm (350 mg/m3);short term exposure limit 250 ppm (600 mg/m3), JUN2005
Occupational Exposure Limit-SWITZERLANDMAK-week 200 ppm (500 mg/m3), KZG-week 400 ppm (1000 mg/m3), JAN2011
Occupational Exposure Limit-THE NETHERLANDSMAC-TGG 650 mg/m3, 2003
Occupational Exposure Limit-THE PHILIPPINEStime-weighted average 400 ppm (980 mg/m3), JAN1993
Occupational Exposure Limit-TURKEYtime-weighted average 200 ppm (500 mg/m3), JAN1993
Occupational Exposure Limit-UNITED KINGDOMtime-weighted average 400 ppm (999 mg/m3);short term exposure limit 500 ppm (1250 mg/m3), OCT2007
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction)8H time-weighted average 400 ppm (980 mg/m3)CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors)8H time-weighted average 400 ppm (980 mg/m3)CFRGBR 41,50-204.50,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry)8H time-weighted average 400 ppm (980 mg/m3)CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards)8H time-weighted average 400 ppm (980 mg/m3)CFRGBR 29,1915.1000,1993

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ISOPROPYL ALCOHOL-air10H time-weighted average 400 ppm;short term exposure limit 500 ppmNIOSH* DHHS #92-100,1992
National Occupational Exposure Survey 1983Hazard Code 40987; Number of Industries 449; Total Number of Facilities 183402; Number of Occupations 278; Total Number of Employees Exposed 4665524; Total Number of Female Employees Exposed 2058264
National Occupational Hazard Survey 1974Hazard Code 40987; Number of Industries 465; Total Number of Facilities 213605; Number of Occupations 252; Total Number of Employees Exposed 3183554

Status in Federal Agencies

OrganizationReference
EPA GENETOX PROGRAM 1988, Negative: Cell transform.-SA7/SHE; N crassa-aneuploidy
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0293-8734;8EHQ-0892-8787
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Alcohols I, 1400
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
OSHA ANALYTICAL METHOD #109
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