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1,3 - Cyclopentadiene

RTECS #: GY1000000

CAS #: 542-92-7


UPDATE: May 2009 MW: 66.11 MF: C5H6


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Cyclopentadiene
  2. Cyclopentadiene (ACGIH:OSHA)
  3. Pentole
  1. Pyropentylene
  2. R - Pentine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 35 mg/m3 Behavioral: Headache VCVGH* -,91,1990
inhalation
human
lowest published toxic concentration: 360 mg/m3 Lung, Thorax, or Respiration: Dyspnea VCVGH* -,91,1990
inhalation
mouse
lethal concentration (50 percent kill): 14 gm/m3 Behavioral: Excitement

Behavioral: Muscle contraction or spasticity

Behavioral: Aggression
GTPZAB 9(12),13,1965
inhalation
mouse
lowest published toxic concentration: 15,000 mg/m3 Behavioral: General anesthetic VCVGH* -,91,1990
inhalation
mouse
lethal concentration (16 percent kill): 9,200 mg/m3 N/R VCVGH* -,91,1990
inhalation
mouse
lethal concentration (50 percent kill): 11,600 mg/m3 N/R VCVGH* -,91,1990
inhalation
mouse
lethal concentration (84 percent kill): 17,000 mg/m3 N/R VCVGH* -,91,1990
inhalation
rat
lethal concentration (50 percent kill): 39 gm/m3 Behavioral: Excitement

Behavioral: Muscle contraction or spasticity

Behavioral: Aggression
GTPZAB 9(12),13,1965
inhalation
rat
lowest published toxic concentration: 60,000 mg/m3 Behavioral: General anesthetic VCVGH* -,91,1990
inhalation
rat
lethal concentration (16 percent kill): 29,000 mg/m3 N/R VCVGH* -,91,1990
inhalation
rat
lethal concentration (50 percent kill): 35,900 mg/m3 N/R VCVGH* -,91,1990
inhalation
rat
lethal concentration (84 percent kill): 44,000 mg/m3 N/R VCVGH* -,91,1990
oral
mouse
lethal dose (50 percent kill): 800 mg/kg N/R TPKVAL 9,27,1967
oral
rat
lethal dose (50 percent kill): 113 mg/kg N/R NTIS** OTS0535718
skin
rabbit
lethal dose (50 percent kill): 430 mg/kg N/R NTIS** OTS0535718


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 350 mg/m3/4 hour/26 week- intermittent Blood: Normocytic anemia

Blood: Changes in erythrocyte (RBC) count
GTPZAB 9(12),13,1965


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 75 ppm DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 75 ppm (200 mg/m3) DTLVS* 3,66,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 75 ppm (200 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 75 ppm (200 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 75 ppm (200 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 75 ppm (200 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 75 ppm (203 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 75 ppm (206 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 75 ppm (200 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 75 ppm (200 mg/m3), short term exposure limit 115 ppm (310 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 75 ppm (200 mg/m3), FEB2006
Occupational Exposure Limit - HUNGARY time-weighted average 200 mg/m3, SEP2000
Occupational Exposure Limit - KOREA time-weighted average 75 ppm (200 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 75 ppm (200 mg/m3);
short term exposure limit 150 ppm (400 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 200 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 75 ppm (203 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 40 ppm (110 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 75 ppm (200 mg/m3), JAN1993
Occupational Exposure Limit - POLAND time-weighted average 200 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 5 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 75 ppm (200 mg/m3), DEC2006
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 75 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 75 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CYCLOPENTADIENE-air 10 hour time-weighted average 75 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 20065;
Number of Industries 19;
Total Number of Facilities 3,138;
Number of Occupations 26;
Total Number of Employees Exposed 18,381
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 20065;
Number of Industries 1;
Total Number of Facilities 3;
Number of Occupations 3;
Total Number of Employees Exposed 51


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in manufacture of resins and in organic synthesis
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: 1,3-Cyclopentadiene, 2523


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Used in manufacture of resins and in organic synthesis

NIOSH PROFILE (ALKENES), SRI, 2/77

NIOSH PROFILE (CYCLOPENTADIENES), SRC, 12/79

NIOSH PROFILE (ALKENES), SRC, 4/78

RTECS Compound Description:
   Human Data

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