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Butane

RTECS #: EJ4200000

CAS #: 106-97-8


UPDATE: May 2009 MW: 58.14 MF: C4H10


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Butane (ACGIH)
  2. Butanen (Dutch)
  3. Butani (Italian)
  1. Diethyl
  2. Methylethylmethane
  3. n - Butane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 280 mg/m3 Brain and Coverings: Changes in surface EEG VCVGH* -,26,1990
inhalation
mouse
lethal concentration (16 percent kill): 530,000 mg/m3/2 hour N/R VCVGH* -,26,1990
inhalation
mouse
lethal concentration (50 percent kill): 680,000 mg/m3/2 hour N/R VCVGH* -,26,1990
inhalation
mouse
lethal concentration (84 percent kill): 860,000 mg/m3/2 hour N/R VCVGH* -,26,1990
inhalation
rat
lethal concentration (16 percent kill): 537,000 mg/m3/4 hour N/R VCVGH* -,26,1990
inhalation
rat
lethal concentration (84 percent kill): 790,000 mg/m3/4 hour N/R VCVGH* -,26,1990
inhalation
rat
lethal concentration (50 percent kill): 658 gm/m3/4 hour N/R ENTOX* -,355,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1000 ppm DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
MUREAV 566,21,2004
TOXICOLOGY REVIEW
ENTOX* -,355,2005
TOXICOLOGY REVIEW
HUTOX* -,577,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 500 ppm (1200 mg/m3) DTLWS* 3,12,1973
Occupational Exposure Limit - AUSTRALIA time-weighted average 800 ppm (1900 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 1000 ppm ( mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 500 ppm (1200 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 800 ppm (1900 mg/m3), short term exposure limit 1000 ppm (2350 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 800 ppm (1900 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 2400 mg/m3 (1000 mL/m3), 2005
Occupational Exposure Limit - HUNGARY time-weighted average 2350 mg/m3, short term exposure limit 9400 mg/m3, SEP2000
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 500 ppm (1200 mg/m3), APR2007
Occupational Exposure Limit - KOREA time-weighted average 800 ppm (1900 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 800 ppm (1900 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1430 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 800 ppm (1900 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 250 ppm (600 mg/m3), JAN1999
Occupational Exposure Limit - POLAND time-weighted average 1900 mg/m3, short term exposure limit 3000 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 300 mg/m3, short term exposure limit 900 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 800 ppm (1900 mg/m3), DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 600 ppm (1450 mg/m3);
short term exposure limit 750 ppm, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 1000 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 1000 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BUTANE-air 10 hour time-weighted average 800 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 13480;
Number of Industries 55;
Total Number of Facilities 5,871;
Number of Occupations 53;
Total Number of Employees Exposed 61,958
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 13480;
Number of Industries 307;
Total Number of Facilities 69,613;
Number of Occupations 200;
Total Number of Employees Exposed 988,880;
Total Number of Female Employees Exposed 186,786


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8.
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
HUTOX*
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

NIOSH PROFILE (PETROLEUM REFINING), FIRL, 4/78

RTECS Compound Description:
   Human Data

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