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Acrylic acid, 2 - hydroxypropyl ester

RTECS #: AT1925000

CAS #: 999-61-1


UPDATE: May 2009 MW: 130.16 MF: C6H10O3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,2 - Propanediol, 1 - acrylate
  2. 2 - Hydroxypropyl acrylate
  3. 2 - Hydroxypropyl acrylate (ACGIH)
  1. 2 - Propenoic acid, 2 - hydroxypropyl ester (9CI)
  2. Propylene glycol monoacrylate
  3. beta - Hydroxypropyl acrylate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lethal dose (50 percent kill): 1,056 mg/kg N/R TOLED5 11,125,1982
oral
rat
lethal dose (50 percent kill): 250 mg/kg N/R 85INA8 5,320,1986
skin
rabbit
lethal dose (50 percent kill): 160 ÁL/kg N/R AIHAAP 30,470,1969


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 ppm (skin, sen) DTLVS* TLV/BEI,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 ppm (2.8 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 ppm (2.8 mg/m3), Skin, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 ppm (3 mg/m3), OCT 2002
Occupational Exposure Limit - FRANCE VME 0.5 ppm (3 mg/m3), Skin, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 0.5 ppm (3 mg/m3), skin, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.5 ppm (3 mg/m3) (skin), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 3 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.5 ppm (2.8 mg/m3), skin, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.5 ppm (2.9 mg/m3), JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 1 mg/m3, short term exposure limit 3 mg/m3, Skin, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 ppm (2.7 mg/m3), Skin, DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 ppm (2.7 mg/m3) (skin), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.5 ppm (skin, sen)
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.5 ppm (skin, sen)


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 2-HYDROXYPROPYL ACRYLATE-air 10 hour time-weighted average 0.5 ppm (Sk) NIOSH* DHHS #92-100,1992


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

85INA8 "Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-

Used in production of plastics and resins

NIOSH PROFILE (ACRYLIC ACID and ESTERS), SRC, 12/79

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