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Paraffin

RTECS #: RV0350000

CAS #: 8002-74-2


UPDATE: May 2009 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. TUMORIGENIC DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Paraffin wax fume
  1. Paraffin wax fume (ACGIH)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
100 mg/24 hour mild JACTDZ 3(3),43,1984
skin
rabbit
500 mg/24 hour mild JACTDZ 3(3),43,1984


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
implant
mouse
toxic dose : 640 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
BJCAAI 17,127,1963
implant
mouse
toxic dose : 660 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
CALEDQ 6,21,1979
implant
mouse
toxic dose : 560 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Kidney, Ureter, and Bladder: Bladder tumors
BJURAN 36,225,1964
implant
rat
lowest published toxic dose: 120 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Kidney, Ureter, and Bladder: Bladder tumors
CNREA8 33,1225,1973


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
JNCIAM 52,1685,1974
TOXICOLOGY REVIEW
ADCSAJ 13,271,1970
TOXICOLOGY REVIEW
ENTOX* -,295,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg/m3 (fume), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg/m3 (fume), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 2 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 1 mg/m3 (fume), JAN1999
Occupational Exposure Limit - FRANCE VME 2 mg/m3 (fume), FEB2006
Occupational Exposure Limit - KOREA time-weighted average 2 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 2 mg/m3;
short term exposure limit 6 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 2 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 2 mg/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 2 mg/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg/m3, DEC2006
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2 mg/m3;
short term exposure limit 6 mg/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 2 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 2 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO PARAFFIN WAX FUME-air 10 hour time-weighted average 2 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0600;
Number of Industries 248;
Total Number of Facilities 42,016;
Number of Occupations 168;
Total Number of Employees Exposed 485,821
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0600;
Number of Industries 237;
Total Number of Facilities 31,266;
Number of Occupations 159;
Total Number of Employees Exposed 703,496;
Total Number of Female Employees Exposed 215,598


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in making candles, as a sealant or coating for paper and food products
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9311
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950-
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947-
BJURAN British Journal of Urology. (Longman Group Ltd., POB 11318, Birmingham, AL 35202) V.1- 1929-
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.

Used in making candles, as a sealant or coating for paper and food products

FDA-over the counter drug

RTECS Compound Description:
   Tumorigen
   Primary Irritant

Click Here for Additional Information about RTECS

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