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Hydrobromic acid

RTECS #: MW3850000

CAS #: 10035-10-6


UPDATE: May 2009 MW: 80.92 MF: BrH


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Acide bromhydrique (French)
  2. Acido bromidrico (Italian)
  3. Anhydrous hydrobromic acid
  4. Bromowodor (Polish)
  1. Bromwasserstoff (German)
  2. Broomwaterstof (Dutch)
  3. Hydrogen bromide
  4. Hydrogen bromide (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lethal concentration (50 percent kill): 814 ppm/1 hour N/R ENTOX* -,537,2005
inhalation
rat
lowest published toxic concentration: 26 mg/m3 Olfaction: Change in sensation of smell

Lung, Thorax, or Respiration: Dyspnea
VCVN5* -,393,1989
inhalation
rat
lethal concentration (50 percent kill): 3,000 ppm/30 minute N/R ENTOX* -,639,2005
inhalation
rat
lethal concentration (50 percent kill): 2,858 ppm/1 hour N/R ENTOX* -,537,2005
inhalation
rat
lowest published toxic concentration: 10 mg/m3/4 hour Lung, Thorax, or Respiration: Other changes TPKVAL 14,73,1975
intraperitoneal
rat
lethal dose (50 percent kill): 76 mg/kg N/R GISAAA 41(1),105,1976


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value ceiling concentration 2 ppm DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
ENTOX* -,639,2005
TOXICOLOGY REVIEW
ENTOX* -,537,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 3 ppm (10 mg/m3) DTLVS* 3,128,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 3 ppm (10 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA ceiling concentration 3 ppm (9.9 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM short term exposure limit 2 ppm (6.7 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK ceiling concentration 2 ppm (6.7 mg/m3), OCT 2002
Occupational Exposure Limit - EC short term exposure limit 2 ppm (6.7 mg/m3), FEB 2006
Occupational Exposure Limit - FINLAND short term exposure limit 3 ppm (10 mg/m3), Skin, JAN1999
Occupational Exposure Limit - FRANCE VLE 2 ppm (6.7 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 6.7 mg/m3 (2 mL/m3), 2005
Occupational Exposure Limit - HUNGARY short term exposure limit 6.7 mg/m3, SEP2000
Occupational Exposure Limit - KOREA ceiling concentration 3 ppm (10 mg/m3), 2006
Occupational Exposure Limit - MEXICO peak 3 ppm (10 mg/m3), 2004
Occupational Exposure Limit - NEW ZEALAND ceiling concentration 3 ppm (9.9 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 3 ppm (10 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 3 ppm (10 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 7 mg/m3, MAC(short term exposure limit) 21 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 2 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 1 ppm (3.5 mg/m3), ceiling concentration 2 ppm (7 mg/m3), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 2 ppm (6,7 mg/m3);
KZG- week 2 ppm (6,7 mg/m3), DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 5 ppm (17 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM short term exposure limit 3 ppm (10 mg/m3), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

ceiling concentration 2 ppm
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
ceiling concentration 2 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO HYDROGEN BROMIDE-air ceiling concentration 3 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 38575;
Number of Industries 13;
Total Number of Facilities 510;
Number of Occupations 12;
Total Number of Employees Exposed 2,643
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 38575;
Number of Industries 23;
Total Number of Facilities 1,103;
Number of Occupations 26;
Total Number of Employees Exposed 20,571;
Total Number of Female Employees Exposed 5,398


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in the manufacture of intermediates for pharmaceuticals, dyes, photographic chemicals
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Acids, inorganic, 7903


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

Used in the manufacture of intermediates for pharmaceuticals, dyes, photographic chemicals

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