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Ethane, 1,1,1 - trichloro -

RTECS #: KJ2975000

CAS #: 71-55-6


UPDATE: May 2009 MW: 133.40 MF: C2H3Cl3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1,1,1 - TCE
  2. 1,1,1 - Trichloorethaan (Dutch)
  3. 1,1,1 - Trichloraethan (German)
  4. 1,1,1 - Trichloroethane
  5. 1,1,1 - Trichloroethane (DOT:OSHA)
  6. 1,1,1 - Tricloroetano (Italian)
  7. Aerothene TT
  8. Analytical grade 1,1,1 - trichloroethane
  9. CF 2
  10. Chloroethene (inhibited)
  11. Chloroform, methyl -
  12. Chlorothene
  13. Chlorothene NU
  14. Chlorothene SM
  15. Chlorothene VG
  16. Chlorten
  17. Ethana NU
  1. F 140a
  2. HCC 140a
  3. ICI - CF 2
  4. Inhibisol
  5. Methyl chloroform
  6. Methyl chloroform (ACGIH:OSHA)
  7. Methylchloroform
  8. Methyltrichloromethane
  9. NCI - C04626
  10. RCRA waste number U226
  11. Solvent 111
  12. Tafclean
  13. Trichloro - 1,1,1 - ethane (French)
  14. Trichloroethane
  15. Trichloromethylmethane
  16. alpha - T
  17. alpha - Trichloroethane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
man
450 ppm/8 hour N/R BJIMAG 28,286,1971
eye
rabbit
100 mg mild AIHAAP 19,353,1958
eye
rabbit
2 mg/24 hour severe 85JCAE -,94,1986
skin
rabbit
5 gm/12 day- intermittent mild AIHAAP 19,353,1958
skin
rabbit
20 mg/24 hour moderate 85JCAE -,94,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis hamster ovary 160 mg/L EMMUEG 10(Suppl 10),1,1987
DNA repair Escherichia coli 500 mg/L PMRSDJ 1,195,1981
mutation in microorganisms mouse lymphocyte 31,300 g/L (+enzymatic activation step) EMMUEG 12(Suppl 13),103,1988
mutation in microorganisms Salmonella typhimurium 10 g/plate (+/-enzymatic activation step) TECSDY 15,101,1987
gene conversion and mitotic recombination Saccharomyes cerevisiae 5,350 mg/L MUREAV 397,271,1998
morphological transform hamster kidney 562 mg/L PMRSDJ 1,626,1981
morphological transform hamster embryo 100 L/plate EVSRBT 25,75,1982
morphological transform mouse embryo 20 mg/L CALEDQ 28,85,1985
morphological transform rat embryo 99 mol/L ITCSAF 14,290,1978


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 2,100 ppm/6 hour (1-20 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) JTEHD6 9,251,1982
inhalation
rat
lowest published toxic concentration: 7,000 ppm/3 hour (13-19 day pregnant) Reproductive: Other effects on female

Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)

Reproductive: Effects on newborn: Behavioral
NETEEC 21,699,1999
oral
rat
lowest published toxic dose: 43 mg/kg (1-22 day pregnant/21 day after birth) Reproductive: Specific developmental abnormalities: Cardiovascular (circulatory) system TJADAB 29(2),25A,1984


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
cat
lethal concentration (50 percent kill): 24,400 mg/m3 N/R GISAAA 35(8),127,1970
inhalation
dog
lowest published toxic concentration: 200 ppm/1 hour Blood: Changes in leukocyte (WBC) count VCVGH* -,375,1990
inhalation
human
lowest published toxic concentration: 920 ppm/70 minute Behavioral: Change in motor activity (specific assay)

Eye: Conjunctiva irritation
AIHAAP 19,353,1958
inhalation
human
lowest published toxic concentration: 11,000 mg/m3/5 minute Behavioral: Ataxia VCVGH* -,375,1990
inhalation
human
lowest published toxic concentration: 2,730 mg/m3/7 hour Eye: Conjunctiva irritation

Behavioral: Somnolence (general depressed activity)

Behavioral: Headache
VCVGH* -,375,1990
inhalation
human
lowest published toxic concentration: 5,440 mg/m3/15 minute Behavioral: Ataxia VCVGH* -,376,1990
inhalation
human
lowest published toxic concentration: 27,200 mg/m3/5 minute Behavioral: General anesthetic VCVGH* -,376,1990
inhalation
man
lowest published toxic concentration: 350 ppm Behavioral: Hallucinations, distorted perceptions

Behavioral: Change in motor activity (specific assay)

Behavioral: Change in psychophysiological tests
WEHRBJ 10,82,1973
inhalation
man
lowest published toxic concentration: 200 ppm/4 hour Behavioral: Change in motor activity (specific assay)

Behavioral: Irritability
ATSUDG 5,96,1982
inhalation
man
lowest published toxic concentration: 200 ppm/4 hour Olfaction: Other olfaction effects IAEHDW 72,485,1999
inhalation
monkey
lethal concentration : >5,000 ppm/7 hour Behavioral: Tremor

Behavioral: Ataxia
AIHOAX 1,225,1950
inhalation
monkey
lowest published toxic concentration: 27,000 mg/m3/1 hour Behavioral: Ataxia VCVGH* -,375,1990
inhalation
monkey
lowest published toxic concentration: 27,000 mg/m3/5 hour Behavioral: Tremor VCVGH* -,375,1990
inhalation
mouse
lethal concentration (50 percent kill): 3,911 ppm/2 hour Behavioral: Excitement SAIGBL 13,226,1971
inhalation
mouse
lowest published toxic concentration: 5,000 ppm/40 minute Brain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Other
JTEHD6 60,331,2000
inhalation
mouse
lowest published toxic concentration: 4,000 ppm/30 minute Behavioral: Ataxia TOSCF2 56,365,2000
inhalation
mouse
lowest published toxic concentration: 12,000 ppm/30 minute Brain and Coverings: Other degenerative changes TOSCF2 56,365,2000
inhalation
mouse
lethal concentration (50 percent kill): 29,492 ppm/10 minute N/R VCVGH* -,374,1990
inhalation
mouse
lowest published toxic concentration: 45,000 mg/m3/2 hour Behavioral: General anesthetic VCVGH* -,374,1990
inhalation
mouse
lowest published lethal concentration: 65,000 mg/m3/2 hour Lung, Thorax, or Respiration: Respiratory depression VCVGH* -,374,1990
inhalation
mouse
lowest published toxic concentration: 7,031 ppm/30 minute Behavioral: Alteration of classical conditioning TXAPA9 193,9,2003
inhalation
mouse
lowest published toxic concentration: 8,000 ppm/30 minute Behavioral: Change in motor activity (specific assay)

Behavioral: Alteration of classical conditioning
TXAPA9 193,9,2003
inhalation
mouse
lowest published toxic concentration: 12,000 ppm/30 minute Peripheral Nerve and Sensation: Sensory change involving segmental distribution

Behavioral: Change in motor activity (specific assay)

Behavioral: Alteration of classical conditioning
TXAPA9 193,9,2003
inhalation
rat
lowest published toxic concentration: 5,000 ppm/40 minute Lung, Thorax, or Respiration: Changes in lung weight

Kidney, Ureter, and Bladder: Changes in kidney weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
JTEHD6 60,331,2000
inhalation
rat
lethal concentration (20 percent kill): 31,000 mg/m3 N/R VCVGH* -,374,1990
inhalation
rat
lethal concentration (50 percent kill): 17,000 ppm/4 hour N/R VCVGH* -,374,1990
inhalation
rat
lethal concentration (50 percent kill): 14,250 ppm/7 hour N/R VCVGH* -,374,1990
inhalation
rat
lethal concentration (50 percent kill): 20,000 ppm/2 hour N/R VCVGH* -,374,1990
inhalation
rat
lowest published toxic concentration: 0.3 pph/4 hour Behavioral: Alteration of classical conditioning VCVGH* -,374,1990
inhalation
rat
lowest published toxic concentration: 1 pph Behavioral: General anesthetic VCVGH* -,374,1990
inhalation
rat
lowest published toxic concentration: 8,000 ppm/7 hour Liver: Fatty liver degeneration VCVGH* -,375,1990
inhalation
rat
lowest published toxic concentration: 72,000 mg/m3/16 minute Behavioral: General anesthetic VCVGH* -,375,1990
inhalation
rat
lowest published lethal concentration: 98,000 mg/m3/5 hour N/R VCVGH* -,375,1990
intraperitoneal
dog
lethal dose (50 percent kill): 3,100 mg/kg Liver: Liver function tests impaired TXAPA9 10,119,1967
intraperitoneal
dog
lethal dose (50 percent kill): 3.1 mL/kg N/R VCVGH* -,374,1990
intraperitoneal
mouse
lethal dose (50 percent kill): 4.9 mg/kg N/R VCVGH* -,374,1990
intraperitoneal
rat
lethal dose (50 percent kill): 3,593 mg/kg N/R ENVRAL 40,411,1986
intraperitoneal
rat
lethal dose (50 percent kill): 3.8 mL/kg N/R VCVGH* -,374,1990
intravenous
dog
lowest published lethal dose: 95 mg/kg N/R HBTXAC 5,72,1959
oral
dog
lethal dose (50 percent kill): 750 mg/kg N/R FMCHA2 -,C310,1991
oral
guinea pig
lethal dose (50 percent kill): 8,600 mg/kg N/R VCVGH* -,374,1990
oral
human
lowest published toxic dose: 670 mg/kg Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Nausea or vomiting

Gastrointestinal: Other changes
NTIS** PB257-185
oral
mammal (species unspecified)
lethal dose (50 percent kill): 5,000 mg/kg N/R VCVGH* -,374,1990
oral
mouse
lethal dose (50 percent kill): 6 gm/kg Cardiac: Pulse rate decreased with fall in BP

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
GNAMAP 29,45,1990
oral
rat
lethal dose (50 percent kill): 9,600 mg/kg Cardiac: Pulse rate decreased with fall in BP

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
GNAMAP 29,45,1990
oral
rat
lowest published toxic dose: 2.5 gm/kg Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) TOSCF2 60,363,2001
oral
rat
lethal dose (50 percent kill): 10.3 gm/kg N/R ENTOX* -,380,2005
oral
rabbit
lethal dose (50 percent kill): 5,660 mg/kg N/R AIHAAP 19,353,1958
subcutaneous
mouse
lethal dose (50 percent kill): 16 gm/kg Behavioral: Sleep

Behavioral: Ataxia
JPETAB 123,224,1958
subcutaneous
mouse
lethal dose (50 percent kill): 16 gm/kg N/R VCVGH* -,374,1990
subcutaneous
rabbit
lowest published lethal dose: 500 mg/kg N/R HBTXAC 5,72,1959
skin
mammal (species unspecified)
lethal dose (50 percent kill): 7,000 mg/kg N/R VCVGH* -,374,1990
skin
rabbit
lowest published lethal dose: 15,800 mg/kg N/R AIHAAP 19,353,1958
unreported route
human
lowest published lethal dose: 0.7 mL/kg N/R VCVGH* -,376,1990
unreported route
human
lowest published toxic dose: 600 mg/kg Gastrointestinal: Hypermotility, diarrhea

Gastrointestinal: Nausea or vomiting
VCVGH* -,376,1990


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
guinea pig
lowest published toxic concentration: 1,000 ppm/1 hour/13 week- intermittent Liver: Other changes AIHAAP 19,353,1958
inhalation
guinea pig
lowest published toxic concentration: 3,000 ppm/7 hour/29 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain AIHOAX 1,225,1950
inhalation
guinea pig
lowest published toxic concentration: 650 ppm/7 hour/58 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain AIHOAX 1,225,1950
inhalation
mouse
lowest published toxic concentration: 1,000 ppm/2 hour/3 week- intermittent Behavioral: Change in motor activity (specific assay)

Liver: Other changes

Blood: Changes in erythrocyte (RBC) count
NEZAAQ 18,175,1963
inhalation
rat
lowest published toxic concentration: 10,000 ppm/1 hour/13 week- intermittent Liver: Other changes AIHAAP 19,353,1958
intramuscular
rat
lowest published toxic dose: 1,200 ppm/30 day- continuous Liver: Changes in liver weight

Brain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Lipids including transport
PHTOEH 67,384,1990
intraperitoneal
mouse
lowest published toxic dose: 8,004 mg/kg/6 day- intermittent Endocrine: Changes in spleen weight

Immunological Including Allergic: Autoimmune (multiple organ involvement)
NTIS** OTS0557868
oral
mouse
lowest published toxic dose: 319 gm/kg/13 week- continuous Nutritional and Gross Metabolic: Weight loss or decreased weight gain NTPTR* NIH-00-4402
oral
rat
lowest published toxic dose: 109 gm/kg/13 week- continuous Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) NTPTR* NIH-00-4402
oral
rat
lowest published toxic dose: 45 gm/kg/9 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
TOSCF2 60,363,2001
oral
rat
lowest published toxic dose: 70 gm/kg/14 day- intermittent Liver: Liver function tests impaired TOSCF2 60,363,2001


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 350 ppm;short term exposure limit 450 ppm DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 20,515,1979
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 71,881,1999
International Agency for Research on Cancer (IARC) Cancer Review Human No Adequate Data IMEMDT 20,515,1979
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 71,881,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMEMDT 71,881,1999
TOXICOLOGY REVIEW
FAZMAE 18,365,1974
TOXICOLOGY REVIEW
EATR** EB-TR-75047
TOXICOLOGY REVIEW
AIHAAP 40(3),A46,1979
TOXICOLOGY REVIEW
MUREAV 543,201,2003
TOXICOLOGY REVIEW
CHHSA* 9,32,2002
TOXICOLOGY REVIEW
DIMON* 39,678,1993
TOXICOLOGY REVIEW
ENTOX* -,380,2005
TOXICOLOGY REVIEW
ENTOX* -,380,2005
TOXICOLOGY REVIEW
MUREAV 584,1,2005
TOXICOLOGY REVIEW
REPTED 25,192,2008
TOXICOLOGY REVIEW
HUTOX* -,683,1996
TOXICOLOGY REVIEW
HUTOX* -,577,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,262,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 350 ppm (1900 mg/m3) DTLVS* 3,161,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 350 ppm (1900 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 350 ppm (1900 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 350 ppm (1900 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 350 ppm (1900 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 100 ppm (555 mg/m3), short term exposure limit 200 ppm (1110 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 100 ppm (555 mg/m3), MAR2002
Occupational Exposure Limit - BELGIUM short term exposure limit 200 ppm (1110 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 50 ppm (275 mg/m3), OCT 2002
Occupational Exposure Limit - EC time-weighted average 555 mg/m3 (100 ppm);
short term exposure limit 1110 mg/m3 (200 ppm), FEB 2006
Occupational Exposure Limit - FINLAND time-weighted average 100 ppm (540 mg/m3), short term exposure limit 250 ppm (1400 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 100 ppm (555 mg/m3), VLE 200 ppm (1110 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 1100 mg/m3 (200 mL/m3), 2005
Occupational Exposure Limit - HUNGARY time-weighted average 555 mg/m3, short term exposure limit 1110 mg/m3, Skin, SEP2000
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 200 ppm (1100 mg/m3), APR2007
Occupational Exposure Limit - KOREA time-weighted average 350 ppm (1900 mg/m3), short term exposure limit 450 ppm (2450 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 350 ppm (1900 mg/m3);
short term exposure limit 450 ppm (2460 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 555 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 125 ppm (680 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 50 ppm (270 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 350 ppm (1900 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 300 mg/m3, MAC(short term exposure limit) 1400 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 20 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 50 ppm (300 mg/m3);
short term exposure limit 90 ppm (500 mg/m3), JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 200 ppm (1080 mg/m3),KZG- week 200 ppm (1080 mg/m3), Skin, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 350 ppm (1900 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 100 ppm (555 mg/m3);
short term exposure limit 200 ppm, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO 1,1,1-TRICHLOROETHANE-air ceiling concentration 350 ppm/15 minute NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 46970;
Number of Industries 412;
Total Number of Facilities 109,850;
Number of Occupations 205;
Total Number of Employees Exposed 1,511,801
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 46970;
Number of Industries 417;
Total Number of Facilities 120,527;
Number of Occupations 243;
Total Number of Employees Exposed 2,528,300;
Total Number of Female Employees Exposed 762,399


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264396)
EPA GENETOX PROGRAM 1988, Positive: Cell transform.-RLV F344 rat embryo
EPA GENETOX PROGRAM 1988, Negative: Sperm morphology-mouse
EPA GENETOX PROGRAM 1988, Inconclusive: Carcinogenicity-mouse/rat; Mammalian micronucleus
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
Used as a cleaning solvent, chemical intermediate for VINYLIDENE CHLORIDE
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH CURRENT INTELLIGENCE BULLETIN 27, 1978
NIOSH Analytical Method, 1994: Hydrocarbons, halogenated, 1003
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
NCI Carcinogenesis Bioassay (gavage);inadequate studies:mouse,rat NCITR* NCI-TR-3,1977
NTP Toxicity studies, RPT# TOX-45, October 2000
NTP Carcinogenesis studies; test completed (post peer review), October 2000
OSHA ANALYTICAL METHOD #14


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
AIHOAX Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.1-2(3), 1950. For publisher information, see AEHLAU.
ATSUDG Archives of Toxicology, Supplement. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) No.1- 1978-
BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944-
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CHHSA* Chemical Health & Safety (Orlando, FL : Published by Elsevier Inc. for the ACS Division of Chemical Health and Safety) V.1- 1994-
DIMON* Disease-a Month (Chicago : Year Book Publishers) V. 24- 1978-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EATR** U.S. Army, Edgewood Arsenal Technical Report. (Aberdeen Proving Ground, MD 21010)
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967-
EVSRBT Environmental Science Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1972-
FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094)
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
GNAMAP Gigiena Naselennykh Mest. Hygiene in Populated Places. (Izdatel'stvo Zdorov'ya, Kiev, USSR) V.7- 1967-
HBTXAC "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59
HUTOX*
IAEHDW International Archives of Occupational and Environmental Health. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.35- 1975-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
ITCSAF In Vitro. (Rockville, MD) V.1-20, 1965-85. For publisher information, see ICDBEO.
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.9- 1987-
NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206-
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Used as a cleaning solvent, chemical intermediate for VINYLIDENE CHLORIDE

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Primary Irritant

ALT CAS #: 74552-83-3
Click Here for Additional Information about RTECS

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