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Ethane, 1,2 - dichloro - 1,1,2,2 - tetrafluoro -

RTECS #: KI1101000

CAS #: 76-14-2


UPDATE: May 2009 MW: 170.92 MF: C2Cl2F4


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. 1,1,2,2 - Tetrafluoro - 1,2 - dichloroethane
  2. 1,2 - Dichloro - 1,1,2,2 - tetrafluoroethane
  3. Arcton 114
  4. Arcton 33
  5. Cryofluoran
  6. Cryofluorane
  7. Dichlorotetrafluoroethane
  8. Dichlorotetrafluoroethane (ACGIH:OSHA)
  9. Ethane, 1,2 - dichlorotetrafluoro -
  10. F 114
  11. FC 114
  12. Fluorane 114
  1. Fluorocarbon 114
  2. Freon 114
  3. Frigen 114
  4. Frigiderm
  5. Genetron 114
  6. Genetron 316
  7. Halocarbon 114
  8. Ledon 114
  9. Propellant 114
  10. R 114
  11. Ucon 114
  12. sym - Dichlorotetrafluoroethane


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
dog
lowest published toxic concentration: 1,444,000 mg/m3/8 hour Behavioral: Convulsions or effect on seizure threshold VCVGH* -,639,1990
inhalation
guinea pig
lethal concentration : >20 pph/8 hour N/R JOCMA7 4,262,1962
inhalation
mouse
lethal concentration (50 percent kill): 70 pph/30 minute N/R EJTXAZ 9,385,1976
inhalation
rat
lethal concentration (50 percent kill): 72 pph/30 minute N/R EJTXAZ 9,385,1976
inhalation
rabbit
lethal concentration (50 percent kill): 75 pph/30 minute N/R EJTXAZ 9,385,1976
oral
rat
lethal dose : >2,250 mg/kg N/R NTIS** OTS0520424


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 1000 ppm DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
ENTOX* -,384,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 1000 ppm (7000 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 1000 ppm (6990 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 1000 ppm (7092 mg/m3), MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 500 ppm (3500 mg/m3), OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 1000 ppm (7000 mg/m3), short term exposure limit 1250 ppm (8750 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 1000 ppm (7000 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 7100 mg/m3 (1000 mL/m3), 2005
Occupational Exposure Limit - HUNGARY Prohibited in Hungary, SEP2000
Occupational Exposure Limit - KOREA time-weighted average 1000 ppm (7000 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 1000 ppm (7000 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 7130 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 1000 ppm (6990 mg/m3), JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 500 ppm (3500 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 5000 mg/m3, MAC(short term exposure limit) 8750 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 3000 mg/m3, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 1000 ppm (7000 mg/m3), DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 1000 ppm (7000 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 1000 ppm (7110 mg/m3);
short term exposure limit 1250 ppm, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO DICHLOROTETRAFLUOROETHANE-air 10 hour time-weighted average 1000 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: T1293;
Number of Industries 2;
Total Number of Facilities 38;
Number of Occupations 2;
Total Number of Employees Exposed 38
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: T1293;
Number of Industries 10;
Total Number of Facilities 1,140;
Number of Occupations 32;
Total Number of Employees Exposed 59,867;
Total Number of Female Employees Exposed 45,860


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: 1,2-Dichlorotetrafluoroethane, 1018


REFERENCES:

CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9.
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
JOCMA7 Journal of Occupational Medicine. (Chicago, IL) V.1-9, 1957-67. For publisher information, see:JJOMDZ
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

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