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Ethanamine

RTECS #: KH2100000

CAS #: 75-04-7


UPDATE: May 2009 MW: 45.10 MF: C2H7N


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. 1 - Aminoethane
  2. Aethylamine (German)
  3. Aminoethane
  4. Ethylamine
  1. Ethylamine (ACGIH:OSHA)
  2. Etilamina (Italian)
  3. Etyloamina (Polish)
  4. Monoethylamine


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
5 mg severe UCDS** 4/25/1958
eye
rabbit
50 ppm/10 day- intermittent severe AMIHBC 3,287,1951
eye
rabbit
250 g/24 hour severe 85JCAE -,429,1986
skin
rabbit
500 mg/24 hour mild 85JCAE -,429,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mammal (species unspecified)
lethal concentration (50 percent kill): 2,300 mg/m3 N/R TPKVAL 14,80,1975
inhalation
rat
lethal concentration (50 percent kill): 5,540 ppm/1 hour Eye: Corneal damage

Lung, Thorax, or Respiration: Dyspnea
NTIS** OTS0538173
inhalation
rat
lethal concentration (50 percent kill): 5,540 ppm/1 hour N/R ENTOX* -,285,2005
intravenous
rabbit
lowest published lethal dose: 350 mg/kg N/R HBAMAK 4,1295,1935
oral
rat
lethal dose (50 percent kill): 400 mg/kg N/R ENTOX* -,285,2005
skin
rabbit
lethal dose (50 percent kill): 390 L/kg N/R AMIHBC 10,61,1954
skin
rabbit
lethal dose (50 percent kill): 270 mg/kg N/R ENTOX* -,285,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm;short term exposure limit 15 ppm (skin) DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
CHREAY 9,389,1931
TOXICOLOGY REVIEW
ENTOX* -,285,2005


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 10 ppm (18 mg/m3) DTLVS* 3,103,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 10 ppm (18 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 ppm (3.8 mg/m3), short term exposure limit 6 ppm (11 mg/m3), JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 5 ppm (9.4 mg/m3), MAR2002
Occupational Exposure Limit - BELGIUM short term exposure limit 15 ppm (28.2 mg/m3), Skin, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 5 ppm (9.2 mg/m3), OCT 2002
Occupational Exposure Limit - EC time-weighted average 5 ppm (9.4 mg/m3), FEB 2006
Occupational Exposure Limit - FINLAND time-weighted average 10 ppm (18 mg/m3), short term exposure limit 20 ppm (37 mg/m3), Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 5 ppm (9.4 mg/m3), VLE 15 ppm (27 mg/m3), FEB2006
Occupational Exposure Limit - GERMANY MAK 9.4 mg/m3 (5 mL/m3), 2005
Occupational Exposure Limit - HUNGARY time-weighted average 9.4 mg/m3, short term exposure limit 9.4 mg/m3, SEP2000
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 10 ppm (18 mg/m3), APR2007
Occupational Exposure Limit - KOREA time-weighted average 10 ppm (18 mg/m3), 2006
Occupational Exposure Limit - MEXICO time-weighted average 10 ppm (18 mg/m3), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 9 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 10 ppm (18 mg/m3), skin, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 10 ppm (18 mg/m3), JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 5 mg/m3, MAC(short term exposure limit) 15 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 10 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 10 ppm (18 mg/m3);
short term exposure limit 15 ppm (30 mg/m3), Skin, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 5 ppm (9 mg/m3),KZG- week 10 ppm (18 mg/m3), DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 10 ppm (18 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2 ppm (3.8 mg/m3);
short term exposure limit 6 ppm (11 mg/m3), 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 5 ppm;
short term exposure limit 15 ppm (skin)
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 5 ppm;
short term exposure limit 15 ppm (skin)


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ETHYLAMINE-air 10 hour time-weighted average 10 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 31520;
Number of Industries 9;
Total Number of Facilities 205;
Number of Occupations 11;
Total Number of Employees Exposed 4,982
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 31520;
Number of Industries 2;
Total Number of Facilities 31;
Number of Occupations 2;
Total Number of Employees Exposed 1,797;
Total Number of Female Employees Exposed 357


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
OSHA ANALYTICAL METHOD #36


REFERENCES:

CODEN
REFERENCE

85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.)
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TPKVAL Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. (Izdatel'stvo Meditsina, Moscow, USSR) No.1- 1961-
UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817)

NIOSH PROFILE (AMINES, PRIMARY ALIPHATIC), SRI, 2/77

RTECS Compound Description:
   Primary Irritant

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