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1,4:5,8 - Dimethanonaphthalene, 1,2,3,4,10,10 - hexachloro - 1,4,4a,5,8,8a - hexahydro - , endo,exo -

RTECS #: IO2100000

CAS #: 309-00-2


UPDATE: May 2009 MW: 364.90 MF: C12H8Cl6


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. REPRODUCTIVE EFFECTS DATA:
  4. TUMORIGENIC DATA:
  5. ACUTE TOXICITY DATA:
  6. OTHER MULTIPLE DOSE DATA:
  7. REVIEWS:
  8. STANDARDS AND REGULATIONS:
  9. NIOSH DOCUMENTATION AND SURVEILLANCE:
  10. STATUS IN FEDERAL AGENCIES:
  11. REFERENCES:

SYNONYMS:

  1. 1,2,3,4,10,10 - Hexachloro - 1,4,4a,5,8,8a - hexahydro - 1,4,5,8 - dimethanonaphthalene
  2. 1,2,3,4,10,10 - Hexachloro - 1,4,4a,5,8,8a - hexahydro - 1,4 - endo - exo - 5,8 - dimethanonaphthalene
  3. 1,2,3,4,10,10 - Hexachloro - 1,4,4a,5,8,8a - hexahydro - exo - 1,4 - endo - 5,8 - dimethanonaphthalene
  4. Aldrex
  5. Aldrex 30
  6. Aldrex 30 E.C.
  7. Aldrin
  8. Aldrin (ACGIH:OSHA)
  9. Aldrine (French)
  10. Aldrite
  11. Aldrosol
  12. Altox
  1. Compound 118
  2. ENT 15,949
  3. HHDN
  4. Hexachlorohexahydro - endo - exo - dimethanonaphthalene
  5. Kortofin
  6. Latka 118 (Czech)
  7. NCI - C00044
  8. Octalene
  9. RCRA waste number P004
  10. SD 2794
  11. Seedrin
  12. Tatuzinho


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
cytogenetic analysis human lymphocyte 19,125 g/L MUREAV 31,103,1975
cytogenetic analysis human leukocyte 19,125 g/L PHTHDT 6,147,1979
cytogenetic analysis intraperitoneal
mouse
9,560 g/kg PHTHDT 6,147,1979
cytogenetic analysis oral
mouse
13 mg/kg IMSCE2 14,1125,1986
cytogenetic analysis intraperitoneal
rat
9,560 g/kg PHTHDT 6,147,1979
DNA damage rat liver 300 mol/L SinJF# 26OCT1982
DNA inhibition human lymphocyte 100 mg/L ARTODN 45,101,1980
DNA inhibition rat other cell types 100 mg/L ARTODN 45,101,1980
unscheduled DNA synthesis human fibroblast 1 mol/L MUREAV 42,161,1977
unscheduled DNA synthesis oral
mouse
11 mol/kg CRNGDP 8,1433,1987
mutation in microorganisms Saccharomyes cerevisiae 5 ppm (-enzymatic activation step) RSTUDV 6,161,1976
micronucleus test intraperitoneal
other fish
3,000 ppm NULSAK 28,176,1985
other mutation test systems oral
mouse
10 mg/kg MUREAV 343,157,1995


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
rat
lowest published toxic dose: 1,950 g/kg (13 day male) Reproductive: Other effects on male

Endocrine: Androgenic
ANDRDQ 20,472,1988
intraperitoneal
rat
lowest published toxic dose: 3,900 g/kg (26 day male) Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands ANDRDQ 20,472,1988
oral
dog
lowest published toxic dose: 73 mg/kg (44 week prior to copulation/1-8 week pregnant) Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth) JAVMA4 123,28,1953
oral
hamster
lowest published toxic dose: 50 mg/kg (7 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Effects on embryo or fetus: Fetal death
TJADAB 9,11,1974
oral
hamster
lowest published toxic dose: 50 mg/kg (7 day pregnant) Reproductive: Specific developmental abnormalities: Eye, ear

Reproductive: Specific developmental abnormalities: Musculoskeletal system

Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)
TJADAB 9,11,1974
oral
mouse
lowest published toxic dose: 25 mg/kg (9 day pregnant) Reproductive: Specific developmental abnormalities: Eye, ear

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TJADAB 9,11,1974
subcutaneous
rat
lowest published toxic dose: 10 mg/kg (2 day prior to copulation) Reproductive: Maternal effects: Uterus, cervix, vagina ENVRAL 16,131,1978
subcutaneous
rat
lowest published toxic dose: 22 mg/kg (1-22 day pregnant) Reproductive: Effects on newborn: Behavioral BJMRDK 22,979,1989
subcutaneous
rat
lowest published toxic dose: 21 mg/kg (21 day after birth) Reproductive: Effects on newborn: Biochemical and metabolic

Reproductive: Effects on newborn: Behavioral
BJMRDK 22,979,1989


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
oral
mouse
lowest published toxic dose: 270 mg/kg/80 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NCITR* NCI-TR-21,1978
oral
mouse
toxic dose : 540 mg/kg/80 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NCITR* NCI-TR-21,1978
oral
rat
lowest published toxic dose: 200 mg/kg/2 year- continuous Tumorigenic: Neoplastic by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Skin and Appendages: Tumors
FCTXAV 2,551,1964
oral
rat
toxic dose : 188 mg/kg/2 year- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Liver: Multiple effects

Lung, Thorax, or Respiration: Other changes
TXAPA9 11,88,1967


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intracerebral
mouse
lethal dose (50 percent kill): 4 mg/kg Behavioral: Convulsions or effect on seizure threshold TOLED5 60,289,1992
inhalation
cat
lethal concentration (50 percent kill): 20 mg/m3 N/R VCVGH* -,567,1990
inhalation
mouse
lethal concentration (50 percent kill): 3 mg/m3 N/R VCVGH* -,567,1990
inhalation
rat
lowest published lethal concentration: 5,800 g/m3/4 hour N/R 85GMAT -,73,1982
inhalation
rat
lethal concentration (50 percent kill): 90 mg/m3 N/R VCVGH* -,567,1990
intraperitoneal
dog
lethal dose (50 percent kill): 1,999 mg/kg Liver: Liver function tests impaired TXAPA9 10,119,1967
intraperitoneal
mouse
lethal dose (50 percent kill): 50 mg/kg N/R SOGEBZ 2,80,1966
intraperitoneal
rat
lethal dose (50 percent kill): 150 mg/kg N/R TXAPA9 11,302,1967
intravenous
mouse
lethal dose (50 percent kill): 21 mg/kg N/R 32ZDAL -,52,1970
oral
wild bird
lethal dose (50 percent kill): 7,200 g/kg N/R TXAPA9 21,315,1972
oral
cat
lowest published lethal dose: 15 mg/kg Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Other changes
CVETAA 2,71,1958
oral
child
lowest published lethal dose: 1,250 g/kg N/R 34ZIAG -,82,1969
oral
chicken
lethal dose (50 percent kill): 10 mg/kg Behavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement

Behavioral: Change in motor activity (specific assay)
JEENAI 45,121,1952
oral
duck
lethal dose (50 percent kill): 520 mg/kg N/R DOEAAH 35,25,1979
oral
dog
lethal dose (50 percent kill): 65 mg/kg N/R PCOC** -,7,1966
oral
guinea pig
lethal dose (50 percent kill): 33 mg/kg N/R PCOC** -,7,1966
oral
hamster
lethal dose (50 percent kill): 100 mg/kg N/R TJADAB 9,11,1974
oral
human
lowest published toxic dose: 14 mg/kg Behavioral: Tremor

Behavioral: Excitement

Gastrointestinal: Nausea or vomiting
34ZIAG -,82,1969
oral
mouse
lethal dose (50 percent kill): 18 mg/kg N/R VCVGH* -,567,1990
oral
pigeon
lethal dose (50 percent kill): 56,200 g/kg N/R ASTTA8 (680),157,1979
oral
quail
lethal dose (50 percent kill): 42,100 g/kg N/R ASTTA8 (680),157,1979
oral
rat
lethal dose (50 percent kill): 38 mg/kg N/R HBPTO* 2,1136,2001
oral
rabbit
lethal dose (50 percent kill): 50 mg/kg N/R PCOC** -,7,1966
subcutaneous
rat
lethal dose (50 percent kill): 62 mg/kg N/R 85GMAT -,73,1982
subcutaneous
rabbit
lowest published lethal dose: 100 mg/kg N/R 85GMAT -,73,1982
skin
cat
lowest published lethal dose: 75 mg/kg Lung, Thorax, or Respiration: Chronic pulmonary edema or congestion

Liver: Fatty liver degeneration

Kidney, Ureter, and Bladder: Other changes
CVETAA 2,71,1958
skin
cat
lethal dose (50 percent kill): 75 mg/kg N/R VCVGH* -,567,1990
skin
rat
lethal dose (50 percent kill): 98 mg/kg N/R TXAPA9 14,515,1969
skin
rabbit
lethal dose (50 percent kill): 15 mg/kg Olfaction: Other olfaction effects

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Excitement
JEENAI 46,702,1953
skin
rabbit
lethal dose (50 percent kill): 84 mg/kg N/R VCVGH* -,567,1990
unreported route
dog
lowest published lethal dose: 95 mg/kg N/R AMIHBC 3,64,1951
unreported route
mammal (species unspecified)
lethal dose (50 percent kill): 40 mg/kg N/R 30ZDA9 -,62,1971


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intramuscular
rat
lowest published toxic dose: 290 mg/kg/58 day- intermittent Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other esterases AMIHBC 9,306,1954
intraperitoneal
rat
lowest published toxic dose: 1,950 g/kg/13 day- intermittent Reproductive: Paternal effects: Testes, epididymis, sperm duct

Reproductive: Paternal effects: Prostate, seminal vesicle, Cowper's gland, accessory glands

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases
ENVPAF 51,87,1988
intraperitoneal
rat
lowest published toxic dose: 3,900 g/kg/26 day- intermittent Related to Chronic Data: Changes in testicular weight ENVPAF 51,87,1988
intraperitoneal
rat
lowest published toxic dose: 1,950 mg/kg/13 day- intermittent Endocrine: Change in LH

Endocrine: Androgenic

Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)
JOENAK 119,75,1988
intraperitoneal
rat
lowest published toxic dose: 3,900 mg/kg/26 day- intermittent Endocrine: Change in gonadotropins JOENAK 119,75,1988
oral
cat
lowest published toxic dose: 91,500 g/kg/61 day- intermittent Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Convulsions or effect on seizure threshold

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
CVETAA 2,71,1958
oral
dog
lowest published toxic dose: 81,120 g/kg/68 week- intermittent Liver: Changes in liver weight JAFCAU 3,402,1955
oral
mouse
lowest published toxic dose: 66 mg/kg/3 day- intermittent Liver: Hepatitis (hepatocellular necrosis), zonal

Liver: Other changes

Liver: Changes in liver weight
TXCYAC 249,176,2008
oral
rat
lowest published toxic dose: 9,100 g/kg/26 week- intermittent Endocrine: Other changes

Blood: Other changes
GISAAA 31(4),13,1966
oral
rat
lowest published toxic dose: 109 mg/kg/2 year- continuous Liver: Changes in liver weight JAFCAU 3,402,1955
oral
rat
lowest published toxic dose: 348 mg/kg/58 day- continuous Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other esterases AMIHBC 9,306,1954


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.05 mg/m3 (inhalable, vapor, skin) DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed animal carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Limited Evidence IMSUDL 7,88,1987
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 5,25,1974
International Agency for Research on Cancer (IARC) Cancer Review Group 3 IMSUDL 7,88,1987
TOXICOLOGY REVIEW
TOLED5 127,101,2002
TOXICOLOGY REVIEW
RREVAH 48,141,1973
TOXICOLOGY REVIEW
RREVAH 56,107,1975
TOXICOLOGY REVIEW
DTTIAF 80,485,1973
TOXICOLOGY REVIEW
BNYMAM 54,413,1978
TOXICOLOGY REVIEW
85CVA2 5,250,1970
TOXICOLOGY REVIEW
CTOXAO 13,231,1978
TOXICOLOGY REVIEW
EESADV 1,89,1977
TOXICOLOGY REVIEW
TXAPA9 10,613,1967
TOXICOLOGY REVIEW
NTIS** PB82-219007
TOXICOLOGY REVIEW
EVHPAZ 109(Suppl 1),113,2001
TOXICOLOGY REVIEW
MUREAV 567,109,2004
TOXICOLOGY REVIEW
26UZAB 6,149,1968/1970
TOXICOLOGY REVIEW
MUTAEX 21,93,2006
TOXICOLOGY REVIEW
ENTOX* -,66,2005
TOXICOLOGY REVIEW
MUREAV 584,1,2005
TOXICOLOGY REVIEW
ENTOX* -,334,2005
TOXICOLOGY REVIEW
HETOEA 25,413,2006
TOXICOLOGY REVIEW
MUREAV 654,114,2008
TOXICOLOGY REVIEW
MUREAV 654,114,2008


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,83,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.25 mg/m3 (skin) DTLVS* 3,7,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.25 mg/m3 (skin) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.25 mg/m3 (skin) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.25 mg/m3 (skin) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.25 mg/m3 (skin) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.25 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.25 mg/m3, Skin, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.25 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.25 mg/m3, short term exposure limit 0.75 mg/m3, Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 0.25 mg/m3, Skin, continuous3 Carcinogen, FEB2006
Occupational Exposure Limit - GERMANY MAK 0.25 mg/m3 (inhalable), 2005
Occupational Exposure Limit - KOREA time-weighted average 0.25 mg/m3, skin, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.25 mg/m3;
short term exposure limit 0.75 mg/m3 (skin), 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.25 mg/m3, Skin, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.25 mg/m3, skin, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.25 mg/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.25 mg/m3, Skin, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.5 mg/m3, short term exposure limit 1.5 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.01 mg/m3, short term exposure limit 0.03 mg/m3, Skin, JUN2003
Occupational Exposure Limit - SWITZERLAND MAK- week 0.25 mg/m3, Skin, DEC2006
Occupational Exposure Limit - THAILAND time-weighted average 0.25 mg/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.25 mg/m3, Skin, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed animal carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed animal carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ALDRIN-air Carcinogen;
10 hour time-weighted average 0.25 mg/m3 (Sk) (0.15 mg/m3 LOQ)
NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 04260;
Number of Industries 1;
Total Number of Facilities 43;
Number of Occupations 8;
Total Number of Employees Exposed 605
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 04260;
Number of Industries 1;
Total Number of Facilities 7;
Number of Occupations 2;
Total Number of Employees Exposed 42;
Total Number of Female Employees Exposed 7


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB/93/182368/AS)
EPA GENETOX PROGRAM 1988, Positive/limited: Carcinogenicity-mouse/rat
EPA GENETOX PROGRAM 1988, Negative: Histidine reversion-Ames test; S cerevisiae-homozygosis
EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal
Used primarily to control soil insects
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Aldrin, 5502
NCI Carcinogenesis Bioassay (feed);clear evidence:mouse NCITR* NCI-TR-21,1978
NCI Carcinogenesis Bioassay (feed);equivocal evidence:rat NCITR* NCI-TR-21,1978


REFERENCES:

CODEN
REFERENCE

26UZAB "Pesticides Symposia; Collection of Papers Presented at the Sixth & Seventh Inter-American Conferences on Toxicology and Occupational Medicine, Miami, FL," Miami, FL, J.L. Halos, 1968-70
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971
32ZDAL "Aldrin Dieldrin Endrin and Telodrin: An Epidemiological and Toxicological Study of Long-Term Occupational Exposure," Jager, K.W., New York, Elsevier Science Pub. Co., 1970
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU.
ANDRDQ Andrologia. (Grosse Verlag GmbH, Kurfuerstenstr. 112-113, D-1000 Berlin 30, Fed. Rep. Ger.) V.6- 1974-
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
ASTTA8 ASTM Special Technical Publication. (American Soc. for Testing Materials, 1916 Race St., Philadelphia, PA 19103) No.1- 1911-
BJMRDK Brazilian Journal of Medical and Biological Research. (Associacao Brasileira de Divulgacao Cientifica, Faculdade de Medicina de Ribeirao Preto, USP, 141000 Ribeirao Preto, SP, Brazil) V.14- 1981-
BNYMAM Bulletin of the New York Academy of Medicine. (New York Academy of Medicine, 2 E. 103rd St., New York, NY 10029) Ser 2: V.1- 1925-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW.
CVETAA Communicationes Veterinariae. (Bogor, Indonesia) V.1-9, 1957-65. Discontinued.
DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970.
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977-
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
ENVPAF Environmental Pollution. (Barking, UK) V.1-20, 1970-79.
ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967-
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
IMSCE2 IRCS Medical Science. (Lancaster, UK) V.12-14, 1984-86. For publisher information, see MSCREJ.
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979-
JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1953-
JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915-
JEENAI Journal of Economic Entomology. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1908-
JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958-
PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS)
PHTHDT Pharmacology and Therapeutics. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 0BW, UK) V.4- 1979-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-
RSTUDV Rivista di Scienza e Technologia degli Alimenti e di Nutrizione Umana. Review of Science and Technology of Food and Human Nutrition. (Bologna, Italy) V.5-6, 1975-76. Discontinued.
SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966-
SinJF# Personal Communication from J.F. Sina, Merck Institute for Therapeutic Research, West Point, PA 19486, Oct. 26, 1982
TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.

Used primarily to control soil insects

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data

ALT CAS #: 34487-55-3
Click Here for Additional Information about RTECS

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