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Carbon Black

RTECS #: FF5800000

CAS #: 1333-86-4


UPDATE: May 2009 MW: N/R MF: N/R


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. REVIEWS:
  7. STANDARDS AND REGULATIONS:
  8. NIOSH DOCUMENTATION AND SURVEILLANCE:
  9. STATUS IN FEDERAL AGENCIES:
  10. REFERENCES:

SYNONYMS:

  1. Acetylene Black
  2. Aroflow
  3. Arogen
  4. Arotone
  5. Arovel
  6. Arrow
  7. Atlantic
  8. Black pearls
  9. C.I. 77266
  10. C.I. Pigment Black 6
  11. C.I. Pigment Black 7
  12. CK3
  13. Cancarb
  14. Carbodis
  15. Carbolac
  16. Carbolac 1
  17. Carbomet
  18. Carbon Black (ACGIH:OSHA)
  19. Carbon Black BV and V
  20. Carbon black, acetylene
  21. Carbon black, channel
  22. Carbon black, furnace
  23. Carbon black, lamp
  24. Carbon black, thermal
  25. Channel Black
  26. Collocarb
  27. Colloidal - carbon
  28. Columbia carbon
  29. Conductex 900
  30. Continex
  31. Corax A
  32. Corax P
  33. Croflex
  34. Crolac
  35. Degussa
  36. Delussa Black FW
  37. Durex O
  38. ELF 78
  39. Eagle Germantown
  40. Elftex
  41. Essex
  42. Excelsior
  43. Explosion Acetylene Black
  44. Explosion Black
  45. Farbruss
  46. Fecto
  47. Flamruss
  48. Furnal
  49. Furnex
  50. Furnex N 765
  51. Gas - furnace black
  52. Gastex
  53. Huber
  54. Humenegro
  55. Impingement Black
  56. Ketjenblack EC
  57. Kosmink
  58. Kosmobil
  59. Kosmolak
  60. Kosmos
  61. Kosmotherm
  62. Kosmovar
  63. Magecol
  64. Metanex
  65. Micronex
  66. Miike 20
  67. Modulex
  68. Mogul
  69. Mogul L
  70. Molacco
  1. Monarch 1300
  2. Neo Spectra Beads AG
  3. Neo - Spectra Mark II
  4. Neotex
  5. Oil - furnace Black
  6. P 33 (carbon black)
  7. P1250
  8. P68
  9. Peach black
  10. Pelletex
  11. Philblack
  12. Philblack N 550
  13. Philblack N 765
  14. Philblack O
  15. Pigment Black 7
  16. Printex
  17. Printex 60
  18. Raven
  19. Raven 30
  20. Raven 420
  21. Raven 500
  22. Raven 8000
  23. Rebonex
  24. Regal
  25. Regal 300
  26. Regal 330
  27. Regal 400R
  28. Regal 600
  29. Regal 99
  30. Regal SRF
  31. Regent
  32. Royal spectra
  33. Sevacarb
  34. Seval
  35. Shawinigan Acetylene Black
  36. Shell carbon
  37. Special Black 1V & V
  38. Special schwarz
  39. Spheron
  40. Spheron 6
  41. Statex
  42. Statex N 550
  43. Sterling MT
  44. Sterling N 765
  45. Sterling NS
  46. Sterling SO 1
  47. Super - carbovar
  48. Super - spectra
  49. Superba
  50. TM 30
  51. Texas
  52. Therma - atomic Black
  53. Thermal Acetylene Black
  54. Thermatomic
  55. Thermax
  56. Thermblack
  57. Tinolite
  58. Toka Black 4500
  59. Toka Black 5500
  60. Toka Black 8500
  61. Torch Brand
  62. Ucet
  63. Ukarb
  64. United
  65. Velvetex
  66. Vulcan
  67. Witco
  68. Witcoblak No. 100
  69. Wyex


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
DNA adduct inhalation
mouse
6,200 g/m3/16 hour/12 week- intermittent EMMUEG 16,64,1990
DNA damage human lymphocyte 16 g/L/48 hour EMMUEG 37,155,2001
DNA damage inhalation
rat
50 g/L/13 week- intermittent TXAPA9 190,224,2003
DNA damage inhalation
rat
50 gm/L/13 week TOXID9 60,194,2001
mutation in microorganisms Salmonella typhimurium 1 mg/plate (+enzymatic activation step) EVSRBT 27,297,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 11,600 g/m3/18 hour/2 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
INHTE5 7,533,1995


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published toxic concentration: 50 mg/m3/6 hour Olfaction: Other olfaction effects TOXID9 44,91,2005
inhalation
rat
lowest published toxic concentration: 7 mg/m3 Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,289,2003
inhalation
rat
lowest published toxic concentration: 1.66 mg/m3/7 hour Lung, Thorax, or Respiration: Sputum

Blood: Changes in leukocyte (WBC) count

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 195,35,2004
inhalation
rat
lowest published toxic concentration: 50 mg/m3 Olfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
inhalation
rat
lowest published toxic concentration: 229 mg/m3/6 hour Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 -,306,2008
intratracheal
mouse
lowest published toxic dose: 1,000 g/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 213,256,2006
intratracheal
rat
lowest published toxic dose: 16 mg/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 44,300,2005
intratracheal
rat
lowest published toxic dose: 15 mg/kg Lung, Thorax, or Respiration: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation)
TOXID9 66,126,2002
intratracheal
rat
lowest published toxic dose: 10 mg/kg Lung, Thorax, or Respiration: Sputum

Biochemical: Metabolism (intermediary): Other proteins

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 207,221,2005
intravenous
rat
lowest published toxic dose: 10 mg/kg/2 minute Liver: Changes in liver weight

Blood: Changes in spleen
XENOBH 10,,1980
intravenous
rat
lowest published toxic dose: 10 mg/kg/2 minute Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) BCPCA6 30,,1981
oral
rat
lethal dose (50 percent kill): >15,400 mg/kg Behavioral: Somnolence (general depressed activity) ATDAEI 15(Suppl 1),S28,1996
skin
rabbit
lethal dose (50 percent kill): >3 gm/kg N/R ATDAEI 15(Suppl 1),S28,1996


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
hamster
lowest published toxic concentration: 7 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,288,2003
inhalation
hamster
lowest published toxic concentration: 50 mg/m3/6 hour/13 week- intermittent Olfaction: Other olfaction effects TOXID9 78,436,2004
inhalation
mouse
lowest published toxic concentration: 1 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation
mouse
lowest published toxic concentration: 1 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation
mouse
lowest published toxic concentration: 7 mg/m3/6 hour/13 week- intermittent Olfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
inhalation
rat
lowest published toxic concentration: 50 mg/m3/6 hour/90 day- intermittent Lung, Thorax, or Respiration: Other changes TOXID9 15,46,1995
inhalation
rat
lowest published toxic concentration: 1 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation
rat
lowest published toxic concentration: 1 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Lung, Thorax, or Respiration: Changes in lung weight

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 66,356,2002
inhalation
rat
lowest published toxic concentration: 50 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other
TOXID9 60,194,2001
inhalation
rat
lowest published toxic concentration: 50 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Other

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 60,194,2001
inhalation
rat
lowest published toxic concentration: 7 mg/m3/6 hour/13 week- intermittent Olfaction: Other olfaction effects

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 78,436,2004
intratracheal
mouse
lowest published toxic dose: 20 mg/kg/4 day- intermittent Lung, Thorax, or Respiration: Sputum

Immunological Including Allergic: Increase in cellular immune response

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 209,51,2005
intratracheal
mouse
lowest published toxic dose: 4,000 g/kg/4 week- intermittent Lung, Thorax, or Respiration: Other changes

Immunological Including Allergic: Increase in cellular immune response

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TXAPA9 209,51,2005
oral
mouse
lowest published toxic dose: 20,000 g/kg/4 week- intermittent Brain and Coverings: Other degenerative changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOLED5 163,153,2006
parenteral
mouse
lowest published toxic dose: 36 g/kg/3 day- intermittent Immunological Including Allergic: Increase in humoral response TOXID9 44,93,2005
skin
rat
lowest published toxic dose: 11 gm/kg/4 week- intermittent Blood: Pigmented or nucleated red blood cells

Liver: Changes in liver weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
NTIS** OTS0534753


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 3.5 mg/m3 DTLVS* TLV/BEI,2007
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Not classifiable as human carcinogen DTLVS* TLV/BEI,2007
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 65,149,1996
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 33,35,1984
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 33,35,1984
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 65,149,1996
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 65,149,1996


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 3.5 mg/m3 DTLVS* 3,38,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 3.5 mg/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 3.5 mg/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 3.5 mg/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 3.5 mg/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 3 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 3.6 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 3.5 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 3.5 mg/m3, short term exposure limit 7 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 3.5 mg/m3, FEB2006
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 1 mg/m3 (respirable), 4 mg/m3 (total), APR2007
Occupational Exposure Limit - KOREA time-weighted average 3.5 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 3.5 mg/m3;
short term exposure limit 7 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 3.5 mg/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 3 mg/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 3.5 mg/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 3.5 mg/m3, JAN1993
Occupational Exposure Limit - RUSSIA short term exposure limit 4 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 3 mg/m3, JUN2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 3.5 mg/m3;
short term exposure limit 7 mg/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Not classifiable as human carcinogen
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Not classifiable as human carcinogen


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CARBON BLACK-air Carcinogen;
10 hour time-weighted average 3.5 mg/m3 in pres. of PAHs
NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0647;
Number of Industries 159;
Total Number of Facilities 19,312;
Number of Occupations 88;
Total Number of Employees Exposed 172,738
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0647;
Number of Industries 376;
Total Number of Facilities 108,610;
Number of Occupations 206;
Total Number of Employees Exposed 1,728,518;
Total Number of Female Employees Exposed 369,253
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X7126;
Number of Industries 1;
Total Number of Facilities 22;
Number of Occupations 1;
Total Number of Employees Exposed 129;
Total Number of Female Employees Exposed 65


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as reinforcing agent and filler for rubber, colorants for ink, paint and plastics
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Carbon black, 5000
OSHA ANALYTICAL METHOD #ID196


REFERENCES:

CODEN
REFERENCE

ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
EVSRBT Environmental Science Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.1- 1972-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
INHTE5 Inhalation Toxicology. (Published by Taylor & Francis Health, 11 New Fetter Lane, London EC4P 4EE) V.1- 1989-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
XENOBH Xenobiotica. (Taylor & Francis Ltd., 4 John St., London WC1N 2ET, UK) V.1- 1971-

Used as reinforcing agent and filler for rubber, colorants for ink, paint and plastics

Top 50 chemical production: 3.02 billions lbs in 1992, 2.72 billions in 1991

NIOSH PROFILE (CARBON BLACK), SRC, 10/77

NIOSH PROFILE (PRINTING INDUSTRY), SRC, 10/77

RTECS Compound Description:
   Tumorigen
   Drug
   Mutagen
   Human Data

Click Here for Additional Information about RTECS

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