CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Antimony

RTECS #: CC4025000

CAS #: 7440-36-0


UPDATE: May 2009 MW: 121.75 MF: Sb


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Antimony (ACGIH:OSHA)
  2. Antimony Black
  3. Antimony metal, super - pure
  4. Antimony, regulus
  1. Antymon (Polish)
  2. C.I. 77050
  3. Stibium


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 50 mg/m3/7 hour/52 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Lung, Thorax, or Respiration: Tumors
JTEHD6 18,607,1986


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 13.5 mg/m3/4 hour Olfaction: Other olfaction effects

Blood: Hemorrhage
VCVN5* -,105,1993
inhalation
human
lowest published toxic concentration: 10 mg/m3/8 hour Behavioral: Muscle weakness

Gastrointestinal: Nausea or vomiting

Nutritional and Gross Metabolic: Body temperature increase
VCVN5* -,105,1993
intraperitoneal
guinea pig
lethal dose (50 percent kill): 150 mg/kg N/R EQSSDX 1,1,1975
intraperitoneal
mouse
lethal dose (50 percent kill): 80 mg/kg N/R VCVN5* -,105,1993
intraperitoneal
rat
lethal dose (50 percent kill): 100 mg/kg N/R 85GMAT -,22,1982
oral
rat
lethal dose (50 percent kill): 100 mg/kg N/R ENTOX* -,148,2005


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
FOREAE 7,313,1942
TOXICOLOGY REVIEW
PTPAD4 1,157,1976
TOXICOLOGY REVIEW
ENTOX* -,148,2005
TOXICOLOGY REVIEW
JJATDK 26,191,2006
TOXICOLOGY REVIEW
HTOPA* 1,701,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 DTLVS* 3,14,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg(Sb)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Sb)/m3, OCT 2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - HUNGARY time-weighted average 0.5 mg/m3, short term exposure limit 2 mg/m3, SEP2000
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 0.1 mg/m3, 2B carcinogen, APR2007
Occupational Exposure Limit - KOREA time-weighted average 0.5 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.5 mg(Sb)/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Sb)/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.5 mg/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Sb)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.5 mg/m3, MAC(short term exposure limit) 1.5 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 0.2 mg/m3, short term exposure limit 0.5 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.5 mg/m3, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg/m3, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 mg(Sb)/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.5 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.5 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO ANTIMONY-air 10 hour time-weighted average 0.5 mg(Sb)/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 07310;
Number of Industries 21;
Total Number of Facilities 2,043;
Number of Occupations 26;
Total Number of Employees Exposed 15,083
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X9115;
Number of Industries 2;
Total Number of Facilities 30;
Number of Occupations 3;
Total Number of Employees Exposed 359
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 07310;
Number of Industries 143;
Total Number of Facilities 21,458;
Number of Occupations 99;
Total Number of Employees Exposed 383,579;
Total Number of Female Employees Exposed 139,736


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

ATSDR TOXICOLOGY PROFILE (NTIS** PB/93/110641/AS)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements in blood or tissue, 8005
OSHA ANALYTICAL METHOD #ID-125G
OSHA ANALYTICAL METHOD #ID121


REFERENCES:

CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ.
HTOPA*
JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PTPAD4 Pharmacology and Therapeutics, Part A: Chemotherapy, Toxicology and Metabolic Inhibitors. (Oxford, UK) V.1-2, 1976-78. For publisher information, see PHTHDT.
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

NIOSH PROFILE (PRINTING INDUSTRY), SRC, 10/77

NIOSH PROFILE (SMELTERS, SECONDARY NON-FERROUS), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Human Data

Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us