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NRI: General Information


Description

From 1940 through the mid to late 1960s, NRI was used to treat hearing loss, chronic otitis, and other conditions among children. It was also used by the military to treat aerotitis media in submariners and aviators. Before 1950, NRI was one of several radiation treatments used to treat benign conditions. Other treatments included use of external x-irradiation to treat hearing loss, acne, tinea capitis, enlarged adenoids, and enlarged thymus, and the use of topical radon and radium to treat hemangiomas. This treatment was discontinued because alternative treatments were developed (T-tubes and better antibiotics) and because of concern about possible radiation carcinogenesis.

Who received the treatment

An estimated 500,000 to 2 million civilians were treated. Treatments began as early as 1940 and continued until the mid to late 1960s. The majority of these civilians were children at the time of treatment. Most of the patients were born before 1960, with the peak use of NRI most likely among children who were born between 1940 and 1950. More than 8,000 World War II servicemen also received NRI.

Typical Treatment description

The goal of treating an individual with NRI was to reduce swollen tissues surrounding the opening of the eustachian tubes. It was thought that reducing the amount of swollen tissue would allow the ears to drain, thereby preventing chronic ear infections that could lead to hearing loss. Typical treatments lasted from 6 to 12 minutes and were commonly repeated at 2 to 3 week intervals with a total of 3 treatments being administered. Occasionally a second course of 3 treatments was given.

Reason for use

NRI was used for areas in which surgeons could not operate. It did not require general anesthesia or hospitalization. NRI was felt to be a safer treatment than conventional X-ray.


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Radiation doses

Radiation doses among adults to nearby organs were estimated on the basis of  50 mg of radium sulfate in two 0.5 mm platinum capsules for 12  - 60 minutes per session for three sessions.


A description of radiation exposure to nearby organs as a result of Nasopharyngeal Radium Irradiation (NRI)


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