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December 5, 2022

Revision of Select Tables from Analysis of Chemicals Found in Cigarette Smoke in a Special Sample of U.S. Adults, NHANES 2011-2016

CDC has revised select tables from the Analysis of Chemicals Found in Cigarette Smoke in a Special Sample of U.S. Adults, NHANES 2011-2016 section of the National Report on Human Exposure to Environmental Chemicals.

The revised tables correct a statistical software programming error affecting estimates for National Health and Nutrition Examination Survey (NHANES) cycles 2013-2014 and 2015-2016. The previous version of the statistical software code omitted 18- and 19-year-olds from two strata: “total population” and “age 18-49 years.”

Tables for the following chemicals were revised:

Tobacco Alkaloids and Metabolites

  • Urinary Total Anabasine
  • Urinary Total Anatabine
  • Urinary Total Cotinine
  • Urinary Total Cotinine N-Oxide
  • Urinary Total trans-3′-Hydroxycotinine
  • Urinary 1-(3-Pyridyl)-1-butanol-4-carboxylic acid (4-Hydroxy-4-(3-pyridyl)-butanoic acid)
  • Urinary Total Nicotine
  • Urinary Total Nicotine 1′-Oxide
  • Urinary Total Nornicotine

Volatile N-Nitrosamine Compounds (VNAs)

  • Urinary N-Nitrosodiethylamine (NDEA)
  • Urinary N-Nitrosoethylmethylamine (NMEA)
  • Urinary N-Nitrosomorpholine (NMOR)
  • Urinary N-Nitrosopiperidine (NPIP)
  • Urinary N-Nitrosopyrrolidine (NPYR)

Volatile Organic Compound (VOC) Metabolites

  • Urinary N-Acetyl-S-(2-carboxyethyl)-L-cysteine
  • Urinary N-Acetyl-S-(3-hydroxypropyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-carbamoylethyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-cyanoethyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-hydroxyethyl)-L-cysteine
  • Urinary N-Acetyl-S-(phenyl)-L-cysteine
  • Urinary N-Acetyl-S-(n-propyl)-L-cysteine
  • Urinary N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine
  • Urinary N-Acetyl-S-(1-hydroxymethyl-2-propenyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-hydroxy-3-butenyl)-L-cysteine
  • Urinary N-Acetyl-S-(4-hydroxy-2-butenyl)-L-cysteine
  • Urinary 2-Thioxothiazolidine-4-carboxylic acid
  • Urinary N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine
  • Urinary 2-Aminothiazoline-4-carboxylic acid
  • Urinary N-Acetyl-S-(N-methylcarbamoyl)-L-cysteine
  • Urinary Phenylglyoxylic acid
  • Urinary N-Acetyl-S-(2-hydroxypropyl)-L-cysteine
  • Urinary N-Acetyl-S-(phenyl-2-hydroxyethyl)-L-cysteine
  • Urinary Mandelic acid
  • Urinary N-Acetyl-S-(trichlorovinyl)-L-cysteine
  • Urinary N-Acetyl-S-(benzyl)-L-cysteine
  • Urinary N-Acetyl-S-(1,2-dichlorovinyl)-L-cysteine
  • Urinary N-Acetyl-S-(2,2-dichlorovinyl)-L-cysteine
  • Urinary N-Acetyl-S-(dimethylphenyl)-L-cysteine
  • Urinary 2-Methylhippuric acid
  • Urinary 3-and 4-Methylhippuric acid
  • Urinary N-Acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine
  • Urinary N-Acetyl-S-(2-hydroxy-3-methyl-3-buten-1-yl)-L-cysteine + N-Acetyl-S-[1-(hydroxymethyl)-2-methyl-2-propen-1-yl]-L-cysteine
  • Urinary N-Acetyl-S-(4-hydroxy-2-methyl-2 buten-1-yl)-L-cysteine

Aromatic Amines

  • Urinary 1-Aminonaphthalene
  • Urinary 2-Aminonaphthalene
  • Urinary 4-Aminobiphenyl
  • Urinary o-Anisidine
  • Urinary 2,6-Dimethylaniline
  • Urinary o-Toluidine
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