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Volume 29, Number 5—May 2023
Research

Use of High-Resolution Geospatial and Genomic Data to Characterize Recent Tuberculosis Transmission, Botswana

Chelsea R. Baker1, Ivan Barilar1, Leonardo S. de Araujo, Anne W. Rimoin, Daniel M. Parker, Rosanna Boyd, James L. Tobias, Patrick K. Moonan, Eleanor S. Click, Alyssa Finlay, John E. Oeltmann, Vladimir N. Minin, Chawangwa Modongo, Nicola M. Zetola2, Stefan Niemann2, and Sanghyuk S. Shin2Comments to Author 
Author affiliations: University of California, Irvine, California, USA (C.R. Baker, D.M. Parker, V.N. Minin, S.S. Shin); Forschungszentrum, Borstel, Germany (I. Barilar, L.S. de Araujo, S. Niemann); University of California, Los Angeles, California, USA (A.W. Rimoin); US Centers for Disease Control and Prevention, Gaborone, Botswana (R. Boyd, A. Finlay); US Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.L. Tobias, P.K. Moonan, R. Boyd, E.S. Click, A. Finlay, J.E. Oeltmann); Botswana–UPenn Partnership, Gaborone (C. Modongo, N.M. Zetola); Victus Global Botswana Organisation, Gaborone (C. Modongo, N.M. Zetola)

Main Article

Figure 7

Correlation between pairwise single-nucleotide polymorphisms (SNP) distance and pairwise geographic distance for genotypic cluster groups ≤5 SNP (A–E) and ungrouped cases (F) in study of high-resolution geospatial and genomic data to characterize recent tuberculosis transmission, Gaborone, Botswana, 2012–2016. Points represent measurements for within-group pairs. There was low positive correlation between pairwise geographic and SNP distances overall (Spearman ρ = 0.1; p = 0.06). SNP, single-nucleotide polymorphism.

Figure 7. Correlation between pairwise single-nucleotide polymorphisms (SNP) distance and pairwise geographic distance for genotypic cluster groups ≤5 SNP (A–E) and ungrouped cases (F) in study of high-resolution geospatial and genomic data to characterize recent tuberculosis transmission, Gaborone, Botswana, 2012–2016. Points represent measurements for within-group pairs. There was low positive correlation between pairwise geographic and SNP distances overall (Spearman ρ = 0.1; p = 0.06). SNP, single-nucleotide polymorphism.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

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