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Volume 29, Number 2—February 2023
Research

Age-Stratified Model to Assess Health Outcomes of COVID-19 Vaccination Strategies, Ghana

Sylvia K. Ofori, Jessica S. Schwind, Kelly L. Sullivan, Gerardo Chowell, Benjamin J. Cowling, and Isaac Chun-Hai FungComments to Author 
Author affiliations: Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA (S.K. Ofori); Georgia Southern University Jiann-Ping Hsu College of Public Health, Statesboro, Georgia, USA (S.K. Ofori, K.L. Sullivan, I.C.-H. Fung); Georgia Southern University Institute for Health Logistics and Analytics, Statesboro (J.S. Schwind); Georgia State University School of Public Health, Atlanta, Georgia, USA (G. Chowell); WHO Collaborating Centre for Infectious Disease Epidemiology and Control, The University of Hong Kong School of Public Health, Pokfulam, Hong Kong (B.J. Cowling)

Main Article

Table 1

Parameter values for age-stratified SEPIARD-V COVID-19 model to assess health outcomes of COVID-19 vaccination strategies, Ghana*

Parameter Symbol Value References
Mean latency period which is the period from exposure to infectiousness
 1/k
 1.85 d
 Abbasi et al. (18), Liu et al. (19)
Mean duration of being infectious and symptomatic
 1/f
 15.7 d
 Cai et al. (20), Xing et al. (21)
Mean duration of being infectious and asymptomatic
 1/q
 7.25 d
 Ma et al. (22), Byrne et al. (23)
Mean duration of being infectious and presymptomatic
 1/c
 2.9 d
 Tindale et al. (24), Byrne et al. (23)
Reproduction number for the initial strain
 R
 3.13
 Armachie et al., unpub. data, https://doi.org/10.20944/preprints202104.0125.v1
Reproduction number for the Delta strain
 R
 5.35
 Pearson et al., unpub. data, https://doi.org/10.1101/2021.12.19.21268038
Probability of exposed person becoming presymptomatically infected
 δ
 0.30
 Chen et al. (25), Buitrago-Garcia et al. (26)
Vaccine efficacy against infection
 σ
 0.745
 Knoll et al. (27)
Relative transmissibility of asymptomatic persons
 u
 0.75
 CDC (28)
Relative transmissibility of presymptomatic persons
 r
 0.75
 CDC (28)
Mean duration of immunity after vaccination
 χ
 182 d
 Iacobucci (29)
Mean duration of immunity after natural infection
 w
 365 d
 Good and Hawkes (30)
Age-specific case-fatality ratio
 z
 0.002 for <25 y, 0.005 for 25–64 y, 0.048 for ≥65 y
 Our World in Data (January 26, 2021–November 12, 2021; 22), Lawal (31)
Daily vaccination rate v Varied by 0.00009–0.0163977 d–1 per person Estimated

*CDC, Centers for Disease Control and Prevention; SEPIARD-V, Susceptible-Exposed-Presymptomatic-Symptomatic-Asymptomatic-Recovered-Dead-Vaccinated.

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