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Volume 23, Number 1—January 2017
Dispatch

Guillain-Barré Syndrome and Healthcare Needs during Zika Virus Transmission, Puerto Rico, 2016

Emilio DirlikovComments to Author , Krista Kniss, Chelsea Major, Dana Thomas, Cesar A. Virgen, Marrielle Mayshack, Jason Asher, Luis Mier-y-Teran-Romero, Jorge L. Salinas, Daniel M. Pastula, Tyler M. Sharp, James Sejvar, Michael A. Johansson, and Brenda Rivera-Garcia
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E. Dirlikov, K. Kniss, C. Major, D. Thomas, M. Mayshack, L. Mier-y-Teran-Romero, J.L. Salinas, D.M. Pastula, T.M. Sharp, J. Sejvar, M.A. Johansson); Puerto Rico Department of Health, San Juan, Puerto Rico (E. Dirlikov, D. Thomas, M. Mayshack, B. Rivera-Garcia); University of California, San Diego, California, USA (C.A. Virgen); Biomedical Advanced Research and Development Authority, Washington, DC, USA (J. Asher); University of Colorado, Denver, Colorado, USA (D.M. Pastula)

Main Article

Table

Estimates of weekly Guillain-Barré syndrome cases and healthcare resource needs, Puerto Rico, 2016

Variable Scenario* Estimate
Median Interquartile range 95% Uncertainty interval
New cases and long-term care patients
Case-patients No Zika virus 1 0–2 0–4
Average week during Zika virus 5 3–6 1–11
Peak week during Zika virus 11 6–17 1–34
Long-term care patients
 No Zika virus 0 0–1 0–2
Average week during Zika virus 2 1–3 0–6
Peak week during Zika virus
 5
 2–8
 0–16
New patient healthcare resource needs
Intravenous immunoglobulin No Zika virus 1 0–2 0–3
Average week during Zika virus 4 3–6 0–10
Peak week during Zika virus 10 5–15 0–30
Mechanical ventilation No Zika virus 0 0–0 0–1
Average week during Zika virus 1 0–2 0–3
Peak week during Zika virus 2 1–4 0–8
Regular ward beds No Zika virus 0 0–1 0–3
Average week during Zika virus 3 1–4 0–7
Peak week during Zika virus 6 3–10 0–21
Intensive care unit beds No Zika virus 0 0–1 0–2
Average week during Zika virus 2 1–3 0–6
Peak week during Zika virus 4 2–7 0–15

*The weekly number of Guillain-Barré syndrome cases and associated healthcare needs were estimated for 3 scenarios: 1) in the absence of Zika virus transmission; 2) in an average week during Zika virus transmission; and 3) during the peak week of Zika virus transmission.

Main Article

Page created: December 14, 2016
Page updated: December 14, 2016
Page reviewed: December 14, 2016
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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