CDC logo, Safer Healthier People  CDC HomeCDC SearchCDC Health Topics A-Z
NIOSH - National Institute for Occupational Safety and Health

Search NIOSH  |  NIOSH Home  |  NIOSH Topics  |  Site Index  |  Databases and Information Resources  |  NIOSH Products  |  Contact Us






Barium sulfate

RTECS #: CR0600000

CAS #: 7727-43-7


UPDATE: February 2009 MW: 233.40 MF: O4SBa


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. TUMORIGENIC DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. REVIEWS:
  7. STANDARDS AND REGULATIONS:
  8. NIOSH DOCUMENTATION AND SURVEILLANCE:
  9. STATUS IN FEDERAL AGENCIES:
  10. REFERENCES:

SYNONYMS:

  1. A 15 (inorganic compound)
  2. Actybaryte
  3. Artificial barite
  4. Artificial heavy spar
  5. BA147
  6. Bakontal
  7. Baridol
  8. Barite
  9. Baritop
  10. Barium sulfate (ACGIH:OSHA)
  11. Barium sulfate (1:1)
  12. Barium sulphate
  13. Barosperse
  14. Barotrast
  15. Baryta White
  16. Barytes
  17. Barytes 22
  18. Bayrites
  19. Blanc fixe
  20. C.I. 77120
  21. C.I. Pigment White 21
  1. Citobaryum
  2. Colonatrast
  3. E - Z - Paque
  4. Enamel White
  5. Esophotrast
  6. Eweiss
  7. Finemeal
  8. Lactobaryt
  9. Liquibarine
  10. Macropaque
  11. Neobar
  12. Oratrast
  13. Permanent White
  14. Precipitated barium sulphate
  15. Raybar
  16. Redi - Flow
  17. Solbar
  18. Sulfuric acid, barium salt (1:1)
  19. Supramike
  20. Travad
  21. Unibaryt


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
micronucleus test intraperitoneal
mouse
12,500 g/kg GWZHEW 12,77,1986


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intrapleural
rat
lowest published toxic dose: 200 mg/kg Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors
BJCAAI 28,173,1973


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intratracheal
mouse
lethal dose : >600 L/kg Lung, Thorax, or Respiration: Other changes OYYAA2 50,123,1995
intratracheal
rat
lowest published lethal dose: 250 mg/kg Lung, Thorax, or Respiration: Fibrosis (interstitial)

Lung, Thorax, or Respiration: Other changes
VCVN1* -,137,1988
intravenous
woman
lowest published lethal dose: 1.25 mL/kg Lung, Thorax, or Respiration: Acute pulmonary edema

Lung, Thorax, or Respiration: Pleural effusion

Lung, Thorax, or Respiration: Respiratory depression
JTCTDW 41,673,2003


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mammal (species unspecified)
lowest published toxic concentration: 250 mg/m3/1 hour/24 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi VCVN1* -,139,1988
inhalation
mammal (species unspecified)
lowest published toxic concentration: 40 mg/m3/8 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi VCVN1* -,139,1988


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
31BYAP -,94,1974
TOXICOLOGY REVIEW
HBTME* ,407,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg(Ba)/m3 DTLVS* 3,21,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 15 mg/m3, total dust CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 5 mg/m3, respirable fraction CFRGBR 29,1915.1000,1993
Occupational Exposure Limit - BELGIUM time-weighted average 10 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg(Ba)/m3, OCT 2002
Occupational Exposure Limit - EC time-weighted average 0.5 mg(Ba)/m3, FEB 2006
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 4 mg/m3 (inhalable), 2005
Occupational Exposure Limit - GERMANY MAK 1.5 mg/m3 (respirable), 2005
Occupational Exposure Limit - GERMANY MAK 0.5 mg(Ba)/m3 (inhalable), 2005
Occupational Exposure Limit - KOREA time-weighted average 0.5 mg(Ba)/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.5 mg(Ba)/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 4 mg/m3 (total dust), 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 1.5 mg/m3 (respirable dust), 2003
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg(Ba)/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 10 mg/m3 (inspirable dust), JAN2002
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.5 mg(Ba)/m3, JAN2002
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg(Ba)/m3, JAN1999
Occupational Exposure Limit - SWEDEN time-weighted average 0.5 mg(Ba)/m3, JUN2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 10 mg/m3 (inhalable), 2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 4 mg/m3 (respirable), 2005
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 mg(Ba)/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 10 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 10 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM SULFATE, respirable fraction-air 10 hour time-weighted average 5 mg/m3 NIOSH* DHHS #92-100,1992
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO BARIUM SULFATE, total dust-air 10 hour time-weighted average 10 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80611;
Number of Industries 173;
Total Number of Facilities 18,620;
Number of Occupations 104;
Total Number of Employees Exposed 188,781
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80611;
Number of Industries 200;
Total Number of Facilities 25,446;
Number of Occupations 133;
Total Number of Employees Exposed 363,169;
Total Number of Female Employees Exposed 96,327


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as raw material source of BARIUM
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

31BYAP "Experimental Lung Cancer: Carcinogenesis and Bioassays, International Symposium, 1974," Karbe, E., and J.F. Park, eds., Springer-Verlag New York, Inc., 1974
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
GWZHEW Gongye Weisheng Yu Zhiyebing. Industrial Health and Occupational Diseases. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1973-
HBTME*
JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967-
VCVN1* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov I-IV groopp" (Hazardous substances. Inornanic substances containing I-IV group elements), Filov V.A., Chimia, 1988.

Used as raw material source of BARIUM

NIOSH PROFILE (BARIUM and ITS COMPOUNDS), SRI, 2/77

RTECS Compound Description:
   Tumorigen
   Drug
   Mutagen
   Human Data

ALT CAS #: 8054-35-1
ALT CAS #: 12751-32-5
Click Here for Additional Information about RTECS

NIOSH Home |  NIOSH Search  |  Site Index  |  Topic List |  Contact Us