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Tellurium

RTECS #: WY2625000

CAS #: 13494-80-9


UPDATE: May 2009 MW: 127.60 MF: Te


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. REVIEWS:
  6. STANDARDS AND REGULATIONS:
  7. NIOSH DOCUMENTATION AND SURVEILLANCE:
  8. STATUS IN FEDERAL AGENCIES:
  9. REFERENCES:

SYNONYMS:

  1. NCI - C60117
  2. Telloy
  3. Tellur (Polish)
  1. Tellurium element
  2. Tellurium (ACGIH:OSHA)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lowest published toxic concentration: 26 mg/kg (9-10 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system VCVN5* -,288,1989
intramuscular
rat
lowest published toxic dose: 13 mg/kg (10 day pregnant) Reproductive: Effects on fertility: Post- implantation mortality (e.g., dead and/or resorbed implants per total number of implants)

Reproductive: Specific developmental abnormalities: Central nervous system
EXPEAM 28,1444,1972
oral
rat
lowest published toxic dose: 3,300 mg/kg (1-22 day pregnant) Reproductive: Specific developmental abnormalities: Central nervous system EXNEAC 31,1,1971
oral
rat
lowest published toxic dose: 1,693 mg/kg (6-15 day pregnant) Reproductive: Specific developmental abnormalities: Craniofacial (including nose and tongue)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
FAATDF 11,691,1988
oral
rat
lowest published toxic dose: 6,064 mg/kg (6-15 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system

Reproductive: Effects on newborn: Other neonatal measures or effects
FAATDF 11,691,1988
oral
rat
lowest published toxic dose: 150 mg/kg (6-15 day pregnant) Reproductive: Other effects on female HBTME* -,815,2007
oral
rat
lowest published toxic dose: 1,500 mg/kg (6-15 day pregnant) Reproductive: Other effects on female

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
HBTME* -,815,2007
oral
rabbit
lowest published toxic dose: 682.5 mg/kg (6-18 day pregnant) Reproductive: Other effects on female HBTME* -,815,2007
oral
rabbit
lowest published toxic dose: 2,047.5 mg/kg (6-18 day pregnant) Reproductive: Other effects on female

Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
HBTME* -,815,2007


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
rat
lethal concentration (50 percent kill): >2,420 mg/m3/4 hour Lung, Thorax, or Respiration: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TNONF* TNO-92-008
intratracheal
rat
lowest published lethal dose: 200 mg/kg Lung, Thorax, or Respiration: Other changes

Liver: Other changes

Kidney, Ureter, and Bladder: Other changes
AIHAAP 39,100,1978
oral
guinea pig
lethal dose (50 percent kill): 45 mg/kg N/R 85GMAT -,107,1982
oral
mouse
lethal dose (50 percent kill): 20 mg/kg N/R 85GMAT -,107,1982
oral
rat
lethal dose (50 percent kill): 83 mg/kg N/R 85GMAT -,107,1982
oral
rabbit
lethal dose (50 percent kill): 67 mg/kg N/R 85GMAT -,107,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
human
lowest published toxic concentration: 0.1 mg/m3/2 year- intermittent Behavioral: Somnolence (general depressed activity)

Behavioral: Anorexia (human)

Lung, Thorax, or Respiration: Fibrosis (interstitial)
VCVN5* -,292,1989
inhalation
rat
lowest published toxic concentration: 3.5 g/m3/24 hour/13 week- continuous Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Liver: Fatty liver degeneration

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects
VCVN5* -,292,1989
inhalation
rat
lowest published toxic concentration: 10 mg/m3/13 week- intermittent Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Lung, Thorax, or Respiration: Other changes

Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
HBTME* -,815,2007
inhalation
rat
lowest published toxic concentration: 50 mg/m3/13 week- intermittent Kidney, Ureter, and Bladder: Hematuria

Blood: Other hemolysis with or without anemia

Blood: Changes in erythrocyte (RBC) count
HBTME* -,815,2007
oral
rat
lowest published toxic dose: 11,250 mg/kg/3 day- intermittent Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Peripheral Nerve and Sensation: Structural change in nerve or sheath
HBTME* -,815,2007


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.1 mg/m3 DTLVS* TLV/BEI,2007
TOXICOLOGY REVIEW
FOREAE 7,313,1942
TOXICOLOGY REVIEW
REPTED 22,196,2006
TOXICOLOGY REVIEW
ENTOX* -,140,2005
TOXICOLOGY REVIEW
HBTME* ,815,2007


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.1 mg/m3 DTLVS* 3,245,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.1 mg(Te)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.1 mg/m3, JUL2008
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 mg(Te)/m3, MAR2002
Occupational Exposure Limit - BELGIUM time-weighted average 0.1 mg/m3, MAR2002
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg(Te)/m3, OCT 2002
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg/m3, OCT 2002
Occupational Exposure Limit - FINLAND time-weighted average 0.1 mg/m3, short term exposure limit 0.3 mg/m3, JAN1999
Occupational Exposure Limit - FRANCE VME 0.1 mg/m3, FEB2006
Occupational Exposure Limit - KOREA time-weighted average 0.1 mg/m3, 2006
Occupational Exposure Limit - MEXICO time-weighted average 0.1 mg/m3, 2004
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.1 mg(Te)/m3, 2003
Occupational Exposure Limit - NEW ZEALAND time-weighted average 0.1 mg/m3, JAN2002
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.01 mg/m3, MAC(short term exposure limit) 0.03 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 0.01 mg/m3, JUN2003
Occupational Exposure Limit - SWEDEN time-weighted average 0.1 mg/m3, JUN2005
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg/m3,KZG- week 0.2 mg/m3, DEC2006
Occupational Exposure Limit - TURKEY time-weighted average 0.1 mg/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.1 mg/m3, 2005
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.1 mg/m3
Occupational Exposure Limit IN SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.1 mg/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO TELLURIUM AND COMPOUNDS-air 10 hour time-weighted average 0.1 mg/m3 NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 71197;
Number of Industries 5;
Total Number of Facilities 192;
Number of Occupations 8;
Total Number of Employees Exposed 472
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 71197;
Number of Industries 10;
Total Number of Facilities 422;
Number of Occupations 16;
Total Number of Employees Exposed 12,284;
Total Number of Female Employees Exposed 3,098


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as additive in ferritic steel production, also used in vulcanization of rubber
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Elements by ICP, 7300
OSHA ANALYTICAL METHOD #ID121


REFERENCES:

CODEN
REFERENCE

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ENTOX* Encyclopedia of Toxicology: Reference Book, Elsevier, 2005
EXNEAC Experimental Neurology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ.
HBTME*
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
REPTED Reproductive Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1987-
TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700 AJ Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands)
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.

Used as additive in ferritic steel production, also used in vulcanization of rubber

NIOSH PROFILE (SMELTERS, SECONDARY NON-FERROUS), SRI, 2/77

RTECS Compound Description:
   Reproductive Effector
   Human Data

ALT CAS #: 137322-20-4
Click Here for Additional Information about RTECS

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