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1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachloroctahydro-

RTECS #
PC8575000
CAS #
143-50-0
See: NMAM or OSHA Methods
Updated
September 2018
Molecular Weight
490.60
Molecular Formula
C10Cl10O
Synonyms
1,1a,3,3a,4,5,5,5a,5b,6-Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
1,2,3,5,6,7,8,9,10,10-Decachloro(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decano-4-one
Chlordecone
Ciba 8514
Clordecone
Compound 1189
Decachloro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
Decachloroketone
Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
Decachloropentacyclo(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decan-4-one
Decachloropentacyclo(5.3.0.0(sup 2,6).0(sup 4,10).0(sup 5,9))decan-3-one
Decachlorotetracyclodecanone
Decachlorotetrahydro-4,7-methanoindeneone
ENT 16,391
GC 1189
General chemicals 1189
Kepone
NCI-C00191
RCRA waste number U142

Mutation Data and Reference

System TestRoute/Organism/TissueDoseReference
other mutation test systemsliver/rat100 µmol/LTIVIEQ 4,179,1990
sister chromatid exchangeovary/hamster1700 µg/LEMMUEG 10(Suppl 10),1,1987
specific locus testintraperitoneal/mouse71.3 µmol/LMUREAV 608,29,2006
sperm morphologyoral/quail200 ppm/42D-continuousTXAPA9 43,535,1978

Reproductive Effects Data and References

Route/OrganismDoseEffectReference
intraperitoneal/rat 25 mg/kg (1D prior to copulation)Reproductive: Other effects on femaleREPTED 5,65,1991
intraperitoneal/rat 50 mg/kg (1D prior to copulation)Reproductive: Maternal effects: Menstrual cycle changes or disorders

Reproductive: Effects on fertility: Mating performance (e.g., # sperm positive females per # females mated; # copulations per # estrus cycles)

Reproductive: Effects on fertility: Female fertility index (e.g., # females pregnant per # sperm positive females; # females pregnant per # females mated)
NTOTDY 8,121,1986
intraperitoneal/rat 50 mg/kg (1D prior to copulation)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)REPTED 1,105,1987/1988
intraperitoneal/rat 75 mg/kg (1D prior to copulation)Reproductive: Maternal effects: Uterus, cervix, vaginaREPTED 5,65,1991
intraperitoneal/rat 60 mg/kg (18-22D preg/7D after birth)Reproductive: Effects on newborn: PhysicalHBPTO* 1,733,2001
intraperitoneal/rat 5 mg/kg (16D pregnant)Reproductive: Effects on newborn: Biochemical and metabolic

Reproductive: Effects on newborn: Behavioral
NETEEC 29,255,2007
oral/mouse 16500 µg/kg (4W male/4W prior to copulation)Reproductive: Effects on fertility: Other measures of fertilityJEENAI 58,754,1965
oral/mouse 120 mg/kg (7-16D pregnant)Reproductive: Effects on embryo or fetus: Fetal death

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TXAPA9 38,189,1976
oral/mouse 100 mg/kg (8-12D pregnant)Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
JTEHD6 10,541,1982
oral/mouse 120 mg/kg (8-12D pregnant)Reproductive: Effects on newborn: Live birth index (Litter size (e.g., # fetuses per litter; measured after birth)

Reproductive: Effects on newborn: Viability index (e.g., # alive at day 4 per # born alive)

Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)
TCMUD8 6,361,1986
oral/mouse 72 mg/kg (30D male/30D prior to copulation)Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)HBPTO* 1,732,2001
oral/rat 105 mg/kg (14-20D pregnant)Reproductive: Specific developmental abnormalities: Endocrine system

Reproductive: Specific developmental abnormalities: Urogenital system

Reproductive: Effects on newborn: Delayed effects
ENVRAL 18,437,1979
oral/rat 40 mg/kg (1D prior to copulation)Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain)VCVGK* -,483,1994
oral/rat 25 mg/kg (7-16D pregnant)Reproductive: Effects on embryo or fetus: Fetal deathVCVGK* -,484,1994
oral/mouse 60 mg/kg (7-16D pregnant)Reproductive: Effects on embryo or fetus: Fetal deathVCVGK* -,484,1994
oral/rat 47 mg/kg (60D pre-12D after birth)Reproductive: Specific developmental abnormalities: Endocrine system

Reproductive: Effects on newborn: Behavioral

Reproductive: Effects on newborn: Delayed effects
NRTXDN 3,131,1982
oral/rat 30.9 mg/kg (60D pre-21D after birth)Reproductive: Specific developmental abnormalities: Endocrine system

Reproductive: Effects on newborn: Delayed effects
NRTXDN 3,119,1982
oral/rat 88.2 mg/kg (7W male)Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)FEPRA7 37,501,1978
oral/rat 63 mg/kg (2-22D preg/21D after birth)Reproductive: Effects on newborn: Biochemical and metabolicTOLED5 4,247,1979
oral/rat 42 mg/kg (2-22D preg/21D after birth)Reproductive: Effects on newborn: Other postnatal measures or effectsTXAPA9 41,142,1977
oral/rat 100 mg/kg (7-16D pregnant)Reproductive: Specific developmental abnormalities: Central nervous system

Reproductive: Specific developmental abnormalities: Urogenital system

Reproductive: Specific developmental abnormalities: Homeostasis
TXAPA9 38,189,1976
oral/rat 60 mg/kg (7-16D pregnant)Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus)

Reproductive: Specific developmental abnormalities: Musculoskeletal system
TXAPA9 38,189,1976
oral/rat 17 mg/kg (1-22D preg/12D after birth)Reproductive: Effects on newborn: BehavioralFEPRA7 40,667,1981
oral/rat 18 mg/kg (5D male)Reproductive: Effects on fertility: Pre- implantation mortality (e.g., reduction in number of implants per female; total number of implants per corpora lutea)

Reproductive: Effects on fertility: Litter size (e.g., # fetuses per litter; measured before birth)
TOLED5 30,237,1986
subcutaneous/rat 2 mg/kg (2D prior to copulation)Reproductive: Maternal effects: Uterus, cervix, vaginaENVRAL 16,131,1978
subcutaneous/rat 10 mg/kg (2D prior to copulation)Reproductive: Maternal effects: Ovaries, fallopian tubesENVRAL 16,131,1978

Tumorigenic Data and References

Route/OrganismDoseEffectReference
oral/mouse lowest published toxic dose: 1200 mg/kg/80W- intermittentTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NCITR* NCI-TR-b,1976
oral/mouse toxic dose: 1340 mg/kg/80W- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
AIHAAP 37,680,1976
oral/mouse toxic dose: 1550 mg/kg/80W- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
AIHAAP 37,680,1976
oral/mouse toxic dose: 1344 mg/kg/80W- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
JTEHD6 4,895,1978
oral/rat lowest published toxic dose: 200 mg/kg/2Y- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NEOLA4 26,231,1979
oral/rat toxic dose: 504 mg/kg/80W- continuousTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors

Skin and Appendages: Tumors
JTEHD6 4,895,1978
oral/rat toxic dose: 670 mg/kg/80W- intermittentTumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors
NCITR* NCI-TR-b,1976

Acute Toxicity Data and References

Route/OrganismDoseEffectReference
implant/mouse lowest published toxic dose: 200 mg/kgEndocrine: Changes in spleen weight

Blood: Changes in spleen

Biochemical: Metabolism (intermediary): Other proteins
TOLED5 183,1,2008
intraperitoneal/mouse lowest published toxic dose: 5 mg/kgLiver: Other changes

Biochemical: Metabolism (intermediary): Other
TOXID9 -,167,2008
intraperitoneal/mouse lowest published toxic dose: 15 mg/kgLiver: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

Biochemical: Metabolism (intermediary): Lipids including transport
TXAPA9 233,193,2008
intraperitoneal/rat lowest published toxic dose: 500 mg/kgReproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)

Reproductive: Paternal effects: Testes, epididymis, sperm duct
HBPTO* 1,733,2001
intraperitoneal/rat lowest published toxic dose: 80 mg/kgBrain and Coverings: Other degenerative changes

Spinal Cord: Other degenerative changes
VCVGK* -,483,1994
intraperitoneal/rat lowest published toxic dose: 50 mg/kgEndocrine: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other enzymes
NRTXDN 8,15,1987
intraperitoneal/rat lowest published toxic dose: 75 mg/kgEndocrine: Changes in adrenal weightNRTXDN 8,15,1987
intraperitoneal/rat lowest published toxic dose: 40 mg/kgBehavioral: TremorPSEBAA 195,44,1990
intraperitoneal/rat lowest published toxic dose: 60 mg/kgEndocrine: Other changes

Blood: Other changes
PSEBAA 195,44,1990
oral/chicken lethal dose (50 percent kill): 480 mg/kgENTOX* -,542,2005
oral/Dog lethal dose (50 percent kill): 250 mg/kgENTOX* -,542,2005
oral/Dog lethal dose (50 percent kill): 250 mg/kgBehavioral: TremorVCVGK* -,483,1994
oral/quail lethal dose (50 percent kill): 237 mg/kgJRPFA4 48,371,1976
oral/rabbit lethal dose (50 percent kill): 65 mg/kgPCOC** -,642,1966
oral/rabbit lethal dose (50 percent kill): 65 mg/kgBehavioral: TremorVCVGK* -,483,1994
oral/rat lethal dose (50 percent kill): 91300 µg/kgNTOTDY 5,91,1983
oral/rat lowest published toxic dose: 40 mg/kgEndocrine: Effect on menstrual cycleVCVGK* -,483,1994
oral/rat lethal dose (50 percent kill): 96 mg/kgBehavioral: TremorVCVGK* -,483,1994
oral/Trout lowest published toxic dose: 0.4 mg/kg/33WEndocrine: EstrogenicTIVIEQ 36,31,1996
skin/rabbit lethal dose (50 percent kill): 345 mg/kgGUCHAZ 6,96,1973
skin/rat lethal dose (50 percent kill): 2000 mg/kgVCVGK* -,483,1994
subcutaneous/rat lowest published toxic dose: 100 mg/kgBehavioral: TremorNRTXDN 3,111,1982
subcutaneous/rat lowest published toxic dose: 100 mg/kgBrain and Coverings: Other degenerative changes

Behavioral: Tremor

Endocrine: Other changes
NRTXDN 3,111,1982
subcutaneous/rat lowest published toxic dose: 75 mg/kgEndocrine: Other changesTXAPA9 100,506,1989
subcutaneous/rat lowest published toxic dose: 100 mg/kgEndocrine: Adrenal cortex hypoplasia

Endocrine: Other changes
NTOTDY 7,33,1985
unreported route/mammal (species unspecified) lowest published toxic dose: 25 mg/kgBrain and Coverings: Other degenerative changesVCVGK* -,483,1994
unreported route/mammal (species unspecified) lethal dose (50 percent kill): 126 mg/kg30ZDA9 -,65,1971

Other Multiple Dose Data and References

Route/OrganismDoseEffectReference
implant/mouse lowest published toxic dose: 400 mg/kg/14W- continuousKidney, Ureter, and Bladder: Renal function tests depressedTXCYAC 218,81,2006
implant/mouse lowest published toxic dose: 40 mg/kg/60D- continuousImmunological Including Allergic: Autoimmune (multiple organ involvement)TXCYAC 218,81,2006
implant/mouse lowest published toxic dose: 120 mg/kg/22W- continuousKidney, Ureter, and Bladder: Renal function tests depressed

Kidney, Ureter, and Bladder: Other changes
TXCYAC 218,81,2006
intraperitoneal/mouse lowest published toxic dose: 83 mg/kg/10D- intermittentReproductive: Maternal effects: Uterus, cervix, vaginaTXAPA9 49,151,1979
intraperitoneal/mouse lowest published toxic dose: 199.8 mg/kg/6D- intermittentReproductive: Maternal effects: Uterus, cervix, vaginaTXAPA9 49,151,1979
intraperitoneal/mouse lowest published toxic dose: 277.6 mg/kg/4D- intermittentReproductive: Maternal effects: Uterus, cervix, vaginaTXAPA9 49,151,1979
intraperitoneal/mouse lowest published toxic dose: 160 mg/kg/20D- intermittentReproductive: Maternal effects: Oogenesis

Reproductive: Maternal effects: Ovaries, fallopian tubes
TOSCF2 68,473,2002
intraperitoneal/mouse lowest published toxic dose: 80 mg/kg/2W- intermittentReproductive: Maternal effects: Ovaries, fallopian tubesTOXID9 60,383,2001
intraperitoneal/rat lowest published toxic dose: 12500 µg/kg/5D- intermittentBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)PCBPBS 18,113,1982
oral/Dog lowest published toxic dose: 560 mg/kg/2.5Y- continuousCardiac: Changes in heart weight

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight
TXAPA9 48,29,1979
oral/hamster lowest published toxic dose: 12 mg/kg/2D- intermittentEndocrine: EstrogenicHBPTO* 1,732,2001
oral/mouse lowest published toxic dose: 240 mg/kg/30D- intermittentEndocrine: Estrogenic

Endocrine: Effect on menstrual cycle
HBPTO* 1,732,2001
oral/mouse lowest published toxic dose: 180 mg/kg/18D- intermittentBehavioral: Ataxia

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
NRTXDN 2,113,1981
oral/mouse lowest published toxic dose: 150 mg/kg/3D- intermittentBrain and Coverings: Other degenerative changes

Behavioral: Tremor

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases
TOLED5 6,275,1980
oral/mouse lowest published toxic dose: 320 mg/kg/10W- intermittentLiver: Changes in liver weightBECTA6 39,615,1987
oral/mouse lowest published toxic dose: 14 mg/kg/14D- continuousBiochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)VCVGK* -,483,1994
oral/mouse lowest published toxic dose: 60 mg/kg/10D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVGK* -,484,1994
oral/mouse lowest published toxic dose: 224 mg/kg/4W- intermittentReproductive: Maternal effects: Ovaries, fallopian tubesVCVGK* -,484,1994
oral/mouse lowest published toxic dose: 175 mg/kg/7W- intermittentLiver: Changes in liver weightTOLED5 255,1,2016
oral/quail lowest published toxic dose: 1470 mg/kg/42D- continuousLiver: Changes in liver weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field

Related to Chronic Data: Changes in testicular weight
TXAPA9 43,535,1978
oral/rat lowest published toxic dose: 126 mg/kg/12W- continuousReproductive: Paternal effects: Testes, epididymis, sperm ductHBPTO* 1,732,2001
oral/rat lowest published toxic dose: 81 mg/kg/90D- continuousReproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count)HBPTO* 1,733,2001
oral/rat lowest published toxic dose: 307 mg/kg/15W- intermittentBehavioral: Alteration of operant conditioning

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Nutritional and Gross Metabolic: Body temperature increase
NTOTDY 5,91,1983
oral/rat lowest published toxic dose: 912 mg/kg/2Y- continuousLiver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
TXAPA9 48,29,1979
oral/rat lowest published toxic dose: 100 mg/kg/10D- intermittentEndocrine: Changes in spleen weight

Blood: Changes in other cell count (unspecified)

Immunological Including Allergic: Decreased immune response
JTEHD6 15,561,1985
oral/rat lowest published toxic dose: 162 mg/kg/90D- continuousBiochemical: Neurotransmitters or modulators (putative): Dopamine in striatumTXAPA9 59,262,1981
oral/rat lowest published toxic dose: 287 mg/kg/35D- continuousLiver: Other changes

Liver: Changes in liver weight
TXAPA9 58,132,1981
oral/rat lowest published toxic dose: 75 mg/kg/3D- intermittentBehavioral: Tremor

Musculoskeletal: Other changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases
BECTA6 25,262,1980
oral/rat lowest published toxic dose: 25 mg/kg/10D- intermittentRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldVCVGK* -,484,1994
oral/rat lowest published toxic dose: 96.12 mg/kg/10D- intermittentNutritional and Gross Metabolic: Weight loss or decreased weight gain

Blood: Other changes
JESEDU A22,639,1987
oral/rat lowest published toxic dose: 49.06 mg/kg/10D- intermittentLiver: Changes in liver weightJESEDU A22,639,1987
oral/rat lowest published toxic dose: 1.68 mg/kg/28D- continuousLiver: Fatty liver degeneration

Liver: Other changes

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)
JTEHD6 6,421,1980
oral/rat lowest published toxic dose: 1600 mg/kg/8D- continuousLiver: Other changes

Endocrine: Other changes
VCVGK* -,484,1994
oral/rat lowest published toxic dose: 140 mg/kg/14D- continuousLiver: Other changes

Endocrine: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain
VCVGK* -,484,1994
oral/rat lowest published toxic dose: 140 mg/kg/14D- continuousLiver: Other changes

Endocrine: Other changes

Reproductive: Paternal effects: Testes, epididymis, sperm duct
VCVGK* -,484,1994
oral/rat lowest published toxic dose: 9 mg/kg/15D- continuousRelated to Chronic Data: Death in the "MULTIPLE DOSE" data type fieldHBPTO* 1,880,2001
oral/rat lowest published toxic dose: 31.5 mg/kg/105D- continuousBrain and Coverings: Other degenerative changesNRTXDN 3,119,1982
oral/rat lowest published toxic dose: 50.4 mg/kg/4W- continuousEndocrine: AndrogenicFEPRA7 37,501,1978
oral/rat lowest published toxic dose: 84 mg/kg/8W- continuousEndocrine: Effect on menstrual cycleFEPRA7 37,501,1978
oral/rat lowest published toxic dose: 105 mg/kg/10W- continuousEndocrine: Estrogenic

Endocrine: Change in LH

Related to Chronic Data: Changes in uterine weight
FEPRA7 37,501,1978
skin/rat lowest published toxic dose: 75 mg/kg/15D- intermittentRelated to Chronic Data: Changes in testicular weightVCVGK* -,484,1994
subcutaneous/mouse lowest published toxic dose: 3 mg/kg/3D- intermittentRelated to Chronic Data: Changes in uterine weight

Endocrine: Estrogenic
EVHPAZ 104,1296,1996
unreported route/mouse lowest published toxic dose: 840 mg/kg/4W- intermittentLiver: Other changes

Liver: Tumors
VCVGK* -,484,1994
unreported route/mouse lowest published toxic dose: 6 mg/kg/10D- continuousReproductive: Maternal effects: Uterus, cervix, vaginaHBPTO* 1,732,2001
unreported route/rat lowest published toxic dose: 700 mg/kg/4W- intermittentBehavioral: TremorVCVGK* -,484,1994
unreported route/rat lowest published toxic dose: 2250 mg/kg/90D- intermittentLiver: Changes in liver weightVCVGK* -,484,1994
unreported route/rat lowest published toxic dose: 730 mg/kg/2Y- intermittentLiver: TumorsVCVGK* -,484,1994

Reviews

OrganizationStandardReference
International Agency for Research on Cancer (IARC)Cancer Review:Animal Sufficient EvidenceIMEMDT 20,67,1979
International Agency for Research on Cancer (IARC)Cancer Review:Human No Adequate DataIMEMDT 20,67,1979
International Agency for Research on Cancer (IARC)Cancer Review:Group 2BIMSUDL 7,56,1987
TOXICOLOGY REVIEWSTEVA8 9,1,1978
TOXICOLOGY REVIEWJTEHD6 4,895,1978
TOXICOLOGY REVIEWCTOXAO 13,231,1978
TOXICOLOGY REVIEWJEPTDQ 2(3),671,1979
TOXICOLOGY REVIEWENTOX* -,542,2005
TOXICOLOGY REVIEWMUREAV 584,1,2005
TOXICOLOGY REVIEWHETOEA 25,413,2006
TOXICOLOGY REVIEWREPTED 26,1,2008
TOXICOLOGY REVIEWMUREAV 672,10,2009
TOXICOLOGY REVIEWMUREAV 672,17,2009
TOXICOLOGY REVIEWHTOPA* 1,501,2002
TOXICOLOGY REVIEWTPHSDY 29,116,2008
TOXICOLOGY REVIEWHETOEA 26,321,2007
TOXICOLOGY REVIEWFESTAS 90,911,2008
TOXICOLOGY REVIEWMUREAV 721,27,2011
TOXICOLOGY REVIEWTOLED5 201,152,2011
TOXICOLOGY REVIEWTXCYAC 307,74,2013
TOXICOLOGY REVIEWTXCYAC 307,123,2013
TOXICOLOGY REVIEWTXAPA9 268,157,2013
TOXICOLOGY REVIEWNETEEC 52,25,2015
TOXICOLOGY REVIEWNETEEC 52,68,2015

Standards and Regulations

OrganizationStandardReference
Occupational Exposure Limit-JAPAN2B carc, MAY2012

NIOSH Documentation and Surveillance

OrganizationStandardReference
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO KEPONE-air10H Carcinogen time-weighted average 0.001 mg/m3NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974Hazard Code M2969; Number of Industries 1; Total Number of Facilities 280; Number of Occupations 2; Total Number of Employees Exposed 12600

Status in Federal Agencies

OrganizationReference
ATSDR TOXICOLOGY PROFILE (NTIS** PB/95/264354)
EPA GENETOX PROGRAM 1988, Inconclusive: Sperm morphology-human
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8899
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Kepone, 5508
NTP 14th Report on Carcinogens,2016:Reasonably anticipated to be human carcinogen
Page last reviewed: November 16, 2018