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Appendix B
CDC and Council of State and Territorial Epidemiologists
(CSTE) pertussis case definition*
Clinical Case Definition
a cough illness lasting at least 2 weeks with one of the following: paroxysms of coughing, inspiratory "whoop," or
posttussive vomiting, and without other apparent cause (as reported by a health-care professional)
Laboratory Criteria for Diagnosis
isolation of Bordetella pertussis from a clinical specimen, or
positive polymerase chain reaction (PCR) assay for
B. pertussis
Case Classification
Confirmed
an acute cough illness of any duration associated with
B. pertussis isolation, or
a case that meets the clinical case definition and is confirmed by PCR, or
a case that meets the clinical definition and is epidemiologically linked directly to a case confirmed by either culture or PCR
Probable
a case that meets the clinical case definition, is not laboratory confirmed by culture or PCR, and is not
epidemiologically linked directly to a laboratory-confirmed case.
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