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Availability of Streptomycin and Para-Aminosalicylic Acid -- United States

Since April 1992, CDC has distributed streptomycin to more than 1000 patients with active tuberculosis under an Investigational New Drug (IND) agreement until licensed, domestic production of streptomycin could be reestablished in the United States. In April 1993, the Food and Drug Administration issued a license allowing Pfizer Inc. to produce and distribute streptomycin. Beginning July 6, 1993, CDC will no longer accept new requests from clinicians to place their patients on streptomycin. Such requests should be directed to Richard Vastola, Roerig Streptomycin Program, Pfizer Pharmaceuticals, Inc., 235 E. 42nd Street, New York, NY 10017; telephone (800) 254-4445. CDC will continue to resupply any patients enrolled in the IND protocol before July 6, 1993, until they have completed their course of streptomycin therapy. Until further notice, CDC will continue to supply para-aminosalicylic acid under a separate IND agreement.

Additional information concerning streptomycin or para-aminosalicylic acid is available from CDC's Drug Service, Scientific Resources Program, National Center for Infectious Diseases, telephone (404) 639-3670.

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