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Preventing Chronic Disease: Public Health Research, Practice and Policy

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Emerging Infectious Diseases Journal


Volume 2: No. 2, April 2005

The Asthma Consultative Process: A Collaborative Approach to Integrating Genomics Into Public Health Practice

This flowchart illustrates how scientific findings are translated into public health practice. The chart flows from left (starting with “Genetic Contribution of Disease”) to right (ending with “Improved Health Outcomes”). An arrow along the top of the chart indicates this left to right progression. In addition, two arrows positioned head to tail in a circle along the bottom of the chart indicate that the five major components of the pathway interact with each other.

Identification of Genetic Component Family history studies Gene discovery Gene function Gene–disease associations
Characteristics of Risk Gene–gene Gene–environment Biologic pathways Multicausal pathways
Intervention Design Clinical trials Clinical management Environmental change Drug development
Implementation & Assessment Education Behavioral change Systems change  
Public & Private Policy Assessment of health care delivery Evaluation of harms/benefits of genetic information    

Figure 1. Translational pathway, which serves to illustrate translation of scientific findings into public health practice.

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The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors’ affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.


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