Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Notice to Readers: Resumption of Routine Schedule for Tetanus and Diphtheria Toxoids

The supply of adult tetanus and diphtheria toxoids (Td) in the United States has become sufficient to permit the resumption of the routine schedule for Td use as recommended by the Advisory Committee on Immunization Practices (1,2). Adolescents and adults for whom routine Td booster doses were deferred should be recalled by their health-care providers to receive the delayed dose. School attendance provisions requiring students to have received a Td booster at age >11 years can be reinstituted.

The Td shortage began in the last quarter of 2000 and resulted from 1) decreased production in 2000 by both U.S. manufacturers (Wyeth Lederle [Pearl River, New York] and Aventis Pasteur [Swiftwater, Pennsylvania]), 2) the decision by Wyeth Lederle to cease Td production in 2001, and 3) the 11-month period required for vaccine production, which led to a lag before increased Td supplies were available from the remaining manufacturer distributing vaccine nationally (Aventis Pasteur) (3--5). The amount of Td distributed nationally decreased 40% during 2001--2002, compared with preshortage distribution levels (Biological Surveillance System, unpublished data, 2002). To ensure vaccine availability for priority indications (3), CDC recommended in May 2001 that all routine Td boosters in adolescents and adults be deferred and that health-care providers record the names of patients whose booster doses were delayed for call-back once Td supplies are restored (5). Health-care providers should review the vaccination status of their patients and administer Td and other indicated vaccines as appropriate.

References

  1. Immunization Practices Advisory Committee. Diphtheria, tetanus, and pertussis: recommendations for vaccine use and other preventive measures---recommendations of the Immunization Practices Advisory Committee (ACIP). MMWR 1991;40(No. RR-10).
  2. CDC. Immunization of adolescents: recommendations of the Advisory Committee on Immunization Practices, the American Academy of Pediatrics, the American Academy of Family Physicians, and the American Medical Association. MMWR 1996;45(No. RR-13).
  3. CDC. Shortage of tetanus and diphtheria toxoids. MMWR 2000;49:1029--30.
  4. CDC. Update on the supply of tetanus and diphtheria toxoids and of diphtheria and tetanus toxoids and acellular pertussis vaccine. MMWR 2001;50:189--90.
  5. CDC. Deferral of routine booster doses of tetanus and diphtheria toxoids for adolescents and adults. MMWR 2001;50:418,427.



Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of Health and Human Services.

References to non-CDC sites on the Internet are provided as a service to MMWR readers and do not constitute or imply endorsement of these organizations or their programs by CDC or the U.S. Department of Health and Human Services. CDC is not responsible for the content of pages found at these sites. URL addresses listed in MMWR were current as of the date of publication.


All MMWR HTML versions of articles are electronic conversions from typeset documents. This conversion might result in character translation or format errors in the HTML version. Users are referred to the electronic PDF version (http://www.cdc.gov/mmwr) and/or the original MMWR paper copy for printable versions of official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.

**Questions or messages regarding errors in formatting should be addressed to mmwrq@cdc.gov.

 
USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO
A-Z Index
  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #