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The content on this page is being archived for historic and reference purposes only. The content, links, and pdfs are no longer maintained and might be outdated.

Notice to Readers: Shortage of Intravenous Penicillin G -- United States

In June 1999, Schein Pharmaceuticals, Inc (Florham Park, New Jersey)* announced that its subsidiary Marsam pharmaceuticals was voluntarily recalling all of its penicillin products to address the Food and Drug Administration's (FDA) regulatory concerns at Schein Pharmaceuticals' manufacturing site. Marsam Pharmaceuticals is a major manufacturer of penicillin G (potassium and sodium) in finished product vials in the United States. It is unknown when this facility will resume distribution of these products. This situation has caused a shortage of these types of penicillin in many parts of the country.

In response to this shortage, FDA has begun to identify and assist alternative manufacturers of these products. Until the product is again available, the existing supplies of penicillin should be used only for patients for whom alternative antibiotics are not appropriate. There is no known shortage of procaine or benzathine penicillin or of oral penicillin preparations. For a few conditions (e.g., congenital syphilis and neurosyphilis, and intrapartum prophylaxis for perinatal group B streptococcal disease), intravenous penicillin G is the drug of choice. Alternative treatment recommendations can be found at http://www.cdc.gov/nchstp/dstd/pencillinG.htm; or by toll-free FAXBACK request, (888) 232-3299.

Disclaimer   All MMWR HTML versions of articles are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the electronic PDF version and/or the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.

**Questions or messages regarding errors in formatting should be addressed to mmwrq@cdc.gov.

Page converted: 10/28/1999

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