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Erratum: Vol. 47, No. RR-4

In the MMWR Recommendations and Reports, "Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection," on page 8 in (Table_2) a typesetting error occurred in the third bulleted item under Category B: Moderately Symptomatic. Following is the corrected table.




Table_2
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Table 2. 1994 Revised human immunodeficiency virus pediatric classification system:
clinical categories *
========================================================================================================================
Category N: Not Symptomatic
Children who have no signs or symptoms considered to be the result of HIV infection or who have only one of
the conditions listed in category A.

Category A: Mildly Symptomatic
Children with two or more of the following conditions but none of the conditions listed in categories B and C:
--Lymphadenopathy (>=0.5 cm at more than two sites; bilateral=one site)
--Hepatomegaly
--Splenomegaly
--Dermatitis
--Parotitis
--Recurrent or persistent upper respiratory infection, sinusitis, or otitis media

Category B: Moderately Symptomatic
Children who have symptomatic conditions other than those listed for category A or category C that are attributed to
HIV infection. Examples of conditions in clinical category B include but are not limited to the following:
--Anemia (<8 gm/dL), neutropenia (<1,000/mm3), or thrombocytopenia (<100,000/mm3) persisting>=30 days
--Bacterial meningitis, pneumonia, or sepsis (single episode)
--Candidiasis, oropharyngeal (i.e., thrush) persisting for 2 months in children aged 6 months
--Cardiomyopathy
--Cytomegalovirus infection with onset before age 1 month
--Diarrhea, recurrent or chronic
--Hepatitis
--Herpes simplex virus (HSV) stomatitis, recurrent (i.e., more than two episodes within 1 year)
--HSV bronchitis, pneumonitis, or esophagitis with onset before age 1 month
--Herpes zoster (i.e., shingles) involving at least two distinct episodes or more than one dermatome
--Leiomyosarcoma
--Lymphoid interstitial pneumonia (LIP) or pulmonary lymphoid hyperplasia complex
--Nephropathy
--Nocardiosis
--Fever lasting 1 month
--Toxoplasmosis with onset before age 1 month
--Varicella, disseminated (i.e., complicated chickenpox)

Category C: Severely Symptomatic
Children who have any condition listed in the 1987 surveillance case definition for acquired immunodeficiency
syndrome, with the exception of LIP (which is a category B condition).
------------------------------------------------------------------------------------------------------------------------
* Modified from: CDC. 1994 Revised classification system for human immunodeficiency virus infection in
  children less than 13 years of age. MMWR 1994;43(no. RR-12):1-10.
========================================================================================================================

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