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Summary of Notifiable Diseases, United States, 1995

Foreword

This publication contains summary tables of the official statistics for the reported occurrence of nationally notifiable diseases in the United States for 1995. These statistics are collected and compiled from reports to the National Notifiable Diseases Surveillance System (NNDSS), which is operated by CDC in collaboration with the Council of State and Territorial Epidemiologists (CSTE). Because the dates of onset and dates of diagnosis for notifiable diseases may not always be reported, these surveillance data are presented by the week that they were reported to CDC by public health officials in state and territorial health departments. These data are finalized and published in the MMWR Summary of Notifiable Diseases, United States for use by state and local health departments; schools of medicine and public health; communications media; local, state, and federal agencies; and other agencies or persons interested in following the trends of reportable diseases in the United States. The annual publication of the Summary also documents which diseases are considered national priorities for notification and the annual number of cases of such diseases.

Part 1 contains information regarding morbidity for each of the diseases considered nationally notifiable during 1995. The tables provide the number of cases of notifiable diseases reported to CDC for 1995, as well as the distribution of cases by month and geographic location and by patient's age, sex, race, and Hispanic ethnicity. The data are final totals as of July 26, 1996, unless otherwise noted. There were no reported cases of anthrax, diphtheria, and yellow fever in the United States during 1995; thus, these three nationally notifiable diseases do not appear in the tables in Part 1. In all tables, leprosy is listed as Hansen disease and tickborne typhus fever is listed as Rocky Mountain spotted fever (RMSF).

Part 2 contains graphs and maps. These graphs and maps depict summary data for many of the notifiable diseases that are described in tabular form in Part 1.

Part 3 includes tables that list the number of cases of notifiable diseases reported to CDC since 1966. It also includes a table enumerating deaths associated with specified notifiable diseases that were reported to the National Center for Health Statistics, CDC, during 1984-1993.

Background

As of January 1, 1995, 49 infectious diseases were designated as notifiable at the national level. A notifiable disease is one for which regular, frequent, and timely information regarding individual cases is considered necessary for the prevention and control of the disease. This section briefly summarizes the history of the reporting of nationally notifiable diseases in the United States.

In 1878, Congress authorized the U.S. Marine Hospital Service (i.e., the forerunner of the Public Health Service {PHS}) to collect morbidity reports regarding cholera, smallpox, plague, and yellow fever from U.S. consuls overseas; this information was to be used for instituting quarantine measures to prevent the introduction and spread of these diseases into the United States. In 1879, a specific Congressional appropriation was made for the collection and publication of reports of these notifiable diseases. The authority for weekly reporting and publication of these reports was expanded by Congress in 1893 to include data from states and municipal authorities. To increase the uniformity of the data, Congress enacted a law in 1902 directing the Surgeon General to provide forms for the collection and compilation of data and for the publication of reports at the national level. In 1912, state and territorial health authorities -- in conjunction with PHS -- recommended immediate telegraphic reporting of five infectious diseases and the monthly reporting, by letter, of 10 additional diseases. The first annual summary of The Notifiable Diseases in 1912 included reports of 10 diseases from 19 states, the District of Columbia, and Hawaii. By 1928, all states, the District of Columbia, Hawaii, and Puerto Rico were participating in national reporting of 29 specified diseases. At their annual meeting in 1950, the State and Territorial Health Officers authorized a conference of state and territorial epidemiologists whose purpose was to determine which diseases should be reported to PHS. In 1961, CDC assumed responsibility for the collection and publication of data concerning nationally notifiable diseases.

The list of nationally notifiable diseases is revised periodically. For example, a disease may be added to the list as a new pathogen emerges, or a disease may be deleted as its incidence declines. Public health officials at state health departments and CDC continue to collaborate in determining which diseases should be nationally notifiable; CSTE, with input from CDC, makes recommendations annually for additions and deletions to the list of nationally notifiable diseases. However, reporting of nationally notifiable diseases to CDC by the states is voluntary. Reporting is currently mandated (i.e., by state legislation or regulation) only at the state level. The list of diseases that are considered notifiable, therefore, varies slightly by state. All states generally report the internationally quarantinable diseases (i.e., cholera, plague, and yellow fever) in compliance with the World Health Organization's International Health Regulations.

CSTE and CDC held a national surveillance conference November 30- December 2, 1994, to review the state of national surveillance for infectious diseases. Conditions that were approved for addition to national surveillance during 1995 are genital infections caused by Chlamydia trachomatis, coccidioidomycosis (for regional surveillance), cryptosporidiosis, hantavirus pulmonary syndrome (HPS), (post-diarrheal) hemolytic-uremic syndrome (HUS), pediatric infection with the human immunodeficiency virus (HIV), invasive group A streptococcal infections, streptococcal toxic-shock syndrome, and invasive infections caused by drug-resistant Streptococcus pneumoniae. These conditions currently are not reportable in all states, and the mechanism for reporting them may not involve clinicians or consist of reports of individual cases, which are the traditional reporting mechanisms. Reports of the number of cases of these conditions -- with the exception of genital infections caused by Chlamydia trachomatis (which has been reportable in many states for a number of years) -- will not appear in the current summary tables; they will, however appear in the 1996 annual summary.

At the 1994 conference, the following diseases were also proposed as deletions from the list of infectious diseases under national surveillance: amebiasis, aseptic meningitis, primary encephalitis (except for arboviral encephalitis), postinfectious encephalitis, granuloma inguinale, unspecified hepatitis, leptospirosis, lymphogranuloma venereum, rheumatic fever, and tularemia. These changes were confirmed by a vote of the full membership of CSTE in early 1995. The number of reported cases of these diseases will not appear in the summary tables for 1995 or for future years.

The list of 52 infectious diseases that were designated as notifiable at the national level at the end of 1995 appears below: *

Acquired immunodeficiency syndrome (AIDS) Anthrax Botulism ** Brucellosis Chancroid Chlamydia trachomatis, genital infection Cholera Coccidioidomycosis ** Congenital rubella syndrome Congenital syphilis Cryptosporidiosis Diphtheria Encephalitis, California Encephalitis, eastern equine Encephalitis, St. Louis Encephalitis, western equine Escherichia coli O157:H7 Gonorrhea Haemophilus influenzae, invasive disease Hansen disease (leprosy) Hantavirus pulmonary syndrome Hemolytic-uremic syndrome, post-diarrheal ** Hepatitis A Hepatitis B Hepatitis, C/non-A, non-B HIV infection, pediatric (i.e., in persons ages less than 13 years) Legionellosis Lyme disease Malaria Measles Meningococcal disease Mumps Pertussis Plague Poliomyelitis, paralytic Psittacosis Rabies, animal Rabies, human Rocky Mountain spotted fever Rubella Salmonellosis ** Shigellosis ** Streptococcal disease, invasive, group A ** Streptococcus pneumoniae, drug-resistant ** Streptococcal toxic-shock syndrome ** Syphilis Tetanus Toxic-shock syndrome Trichinosis Tuberculosis Typhoid fever Yellow fever **

  • Although varicella is not a nationally notifiable disease, the Council of State and Territorial Epidemiologists recommends reporting of cases of this disease to CDC. ** Not currently published in the weekly tables.

Data Sources

Provisional data concerning the reported occurrence of notifiable diseases are published weekly in MMWR. After each reporting year, staff in state health departments finalize reports of cases for that year with local or county health departments and reconcile the data with reports previously sent to CDC throughout the year; these data are compiled in final form in this summary. Notifiable disease reports are published in the annual MMWR Summary of Notifiable Diseases only after approval by the appropriate epidemiologist from each submitting state or territory and are the authoritative and archival counts of cases. Data published in MMWR Surveillance Summaries or other surveillance reports produced by CDC programs, which are useful for detailed epidemiologic analyses, may not agree exactly with data reported in the annual Summary of Notifiable Diseases because of differences in the timing of reports, the source of the data, and the use of different case definitions.

Data in this summary were derived primarily from reports transmitted to the Division of Surveillance and Epidemiology, Epidemiology Program Office, CDC, by the health departments of 50 states, two cities, and five territories through the National Electronic Telecommunications System for Surveillance (NETSS). Final data for other diseases are from the surveillance-program records of the following CDC programs (requests for further information regarding these data should be directed to the source specified):

National Center for Health Statistics

Office of Vital and Health Statistics Systems (deaths from selected

notifiable diseases)

National Center for Infectious Diseases

Division of Bacterial and Mycotic Diseases (toxic-shock syndrome

and laboratory data regarding botulism, Escherichia coli O157:H7, Salmonella, Shigella, and penicillin-nonsusceptible S. pneumoniae {PNSP}) Division of HIV/AIDS Division of Vector-Borne Infectious Diseases (laboratory data

regarding arboviral encephalitis) Division of Viral and Rickettsial Diseases (animal rabies)

National Center for HIV, STD, and TB Prevention (NCHSTP)

Division of Sexually Transmitted Diseases Prevention (chancroid,

chlamydia, gonorrhea, and syphilis) Division of Tuberculosis Elimination (tuberculosis)

National Immunization Program

Epidemiology and Surveillance Division (poliomyelitis)

Disease totals for the United States, unless otherwise stated, do not include data for American Samoa, Guam, Puerto Rico, the Virgin Islands, and the Commonwealth of the Northern Mariana Islands (CNMI). Disease totals from American Samoa were unavailable for 1995.

Population estimates for states are based on the July 1, 1995, post-censal estimates made by the U.S. Department of Commerce, Bureau of the Census, Population Division, Population Estimates Branch, Press Release CB94-204. Because these estimates are unavailable by age and sex for 1995, rates for reported disease occurrences by age group and among males and females use population totals from the July 1, 1993, post-censal estimates. Population estimates for territories are from the 1990 census, U.S. Department of Commerce, Bureau of the Census, Press Releases CB91-142, 242, 243, 263, and 276.

Rates in the 1995 Summary of Notifiable Diseases were based on data for the U.S. total-resident population. However, population data from states in which diseases were not notifiable or disease data were not available were excluded from rate calculations.

Interpreting Data

The data reported in this summary are useful for analyzing disease trends and determining relative disease burdens. However, these data must be interpreted in light of reporting practices. Some diseases that cause severe clinical illness (e.g., plague or rabies), if diagnosed by a clinician, are likely to be reported accurately. However, persons who have diseases that are clinically mild and infrequently associated with serious consequences (e.g., salmonellosis) may not even seek medical care from a health-care provider; even if these less severe diseases are diagnosed, they are less likely to be reported. The degree of completeness of reporting also is influenced by the diagnostic facilities that are available; the control measures that are in effect; the public awareness of a specific disease; and the interests, resources, and priorities of state and local officials responsible for disease control and public health surveillance. Finally, factors such as changes in the case definitions for public health surveillance, the introduction of new diagnostic tests, or the discovery of new disease entities may cause changes in disease reporting that are independent of the true incidence of disease.

Public health surveillance data are published for selected racial and ethnic population groups because these variables may be risk markers for certain notifiable diseases. Risk markers can identify potential risk factors for investigation in future studies. Data regarding race and ethnicity also can be useful for identifying groups to target for prevention efforts. However, caution must also be used when drawing conclusions from reported data relating to race and ethnicity. Among certain races and ethnicities, there are likely to be differential patterns of access to health care, interest in seeking health care, and detection of disease that would lead to data that are not representative of disease incidence in these populations. In addition, not all data concerning race and ethnicity are collected uniformly for all diseases. For example, the Division of HIV/AIDS Prevention and the Division of STD Prevention in NCHSTP collect information regarding race and ethnicity using a single variable instead of two separate variables. A person's racial and ethnic background is reported as either American Indian/Alaskan Native, Asian/Pacific Islander, Black non-Hispanic, White non-Hispanic, or Hispanic. Additionally, although the recommended standard for classifying a person's race or ethnicity is based on self-reporting, it is not clear that this procedure is always followed.

Highlights for Selected Infectious Diseases

Arboviral Encephalitis

In 1995, a case of encephalitis caused by Cache Valley virus was reported in North Carolina. Although this mosquito-borne bunyavirus was previously known to cause subclinical infections in humans, no clinical cases had been recognized previously.

Coccidioidomycosis

In 1995, the CSTE recommended that coccidioidomycosis become a regionally reportable disease. Because the Emerging Infectious Program at the National Center for Infectious Diseases (NCID/CDC), in collaboration with the State of California Department of Health Services, has been conducting active surveillance for coccidioidomycosis in Kern County, California, for some time, its data are presented. The total number of coccidioidomycosis cases reported to the Kern County Health Department during 1995 was 770; this represents a drop in the number of cases when compared with the large number reported in the epidemic years during 1991- 1994 (e.g., during 1992, a peak of 3,342 cases occurred in Kern County alone).

Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob disease (CJD) is a subacute, degenerative disease of the brain that is classified as a transmissible, spongiform encephalopathy. More than 85% of CJD patients die within 1 year of onset. From 1979 through 1994, there were 3,642 CJD-related deaths in the United States (based on national data concerning multiple causes of death and a preliminary total of 280 deaths in 1994). The average annual age-adjusted death rate attributed to CJD is 0.95 deaths per million persons. As of September 15, 1996, evidence does not indicate that cases of the newly described variant of CJD (i.e., the type identified in the United Kingdom) have occurred in the United States. This evidence is based on the analysis of both national data and data from active, retrospective surveillance for CJD conducted since 1991 by special surveillance teams in five areas of the country (1993 population: 16.3 million persons).

Cryptosporidiosis

National reporting of cryptosporidiosis began in 1995. During 1995, it was reportable in 24 of 50 states; however, many other states have made or are in the process of making cryptosporidiosis a notifiable disease. Because the diagnosis of cryptosporidiosis is often not considered, and because most laboratories do not routinely test for Cryptosporidium infection, cryptosporidiosis will continue to be underdiagnosed and underreported.

Dengue and Dengue Hemorrhagic Fever

In 1995, most tropical countries in the Americas reported major outbreaks of dengue and dengue hemorrhagic fever (DHF). During this period, the Pan American Health Organization received reports of over 250,000 total cases of dengue and DHF from member countries. This was the largest number reported since 1981, when the worst epidemic in the Americas occurred in Cuba. As a result of this widespread activity, the number of laboratory-positive cases of imported dengue in the United States increased to 86 in 1995 from 37 in 1994. During 1995, the Texas State Health Department reported eight laboratory-positive cases resulting from local transmission by Aedes aegypti mosquitoes. Dengue transmission in the continental United States had not been reported since 1986.

Hantavirus Pulmonary Syndrome

Hantavirus pulmonary syndrome (HPS) is now recognized as a pan-American viral zoonosis caused by Sin Nombre virus and other New World hantaviruses. The identified rodent reservoirs for these viruses are as follows: Peromyscus maniculatus and P. leucopus (deer mouse and white-footed mouse, respectively) for Sin Nombre virus and its variants; Sigmodon hispidus (cotton rat) for Black Creek Canal virus; and Oryzomys palustris (rice rat) for Bayou virus. Cases of HPS have been found throughout the continental United States, in Canada, and in South America. As of August 22, 1996, national surveillance for HPS has identified 143 confirmed case-patients in 25 states (case-fatality rate: 50.2%); 23 of these cases occurred in 1995.

Hemolytic-Uremic Syndrome

Infection caused by Shiga toxin-producing E. coli (i.e., STEC), especially serotype O157:H7, is the leading cause of hemolytic-uremic syndrome (HUS) in the United States. Although an estimated 1,200 HUS cases caused by infectious agents occur in the United States each year, the absence of longstanding surveillance data has limited the assessment of HUS as a public health problem. When surveyed in August 1994, only 15 states listed HUS as a notifiable disease. Recent efforts to improve surveillance include the creation of a unique International Classification of Diseases code for HUS; the adoption of a uniform, post-diarrheal case definition for HUS by the CSTE; and the recommendation by CSTE, in 1995, that HUS be made a notifiable disease in all states. Efforts are also underway to establish active surveillance for HUS in selected states.

HIV Infection in Children and Infants

In 1994, results of the AIDS Clinical Trials Group Protocol 076 indicated that administering zidovudine to a selected group of pregnant, HIV-infected women, and subsequently to their newly born infants, reduced the risk for perinatal HIV transmission to these infants by two thirds. The U.S. Public Health Service (USPHS) subsequently issued guidelines for the use of zidovudine to reduce perinatal transmission of HIV (MMWR 1994;43{No. RR-11}:1-20) and the routine counseling and voluntary HIV testing of all pregnant women (MMWR 1995;44{No. RR-7}:1-15). USPHS also issued revised guidelines on PCP prophylaxis for children (MMWR 1995;44 {No. RR-4}:1-11) that recommends each child born to an HIV-infected mother receive PCP prophylaxis until the child's HIV status is determined. States that conduct surveillance of pediatric HIV exposure/infection should be able to evaluate the implementation and impact of these guidelines most effectively and enhance early identification of HIV status in infants. In 1995, 28 states conducted surveillance of HIV infection in children. These states reported 332 HIV-infected children who had not progressed to acquired immunodeficiency syndrome (AIDS) and 229 children who had AIDS.

Penicillin-Nonsusceptible S. pneumoniae

The prevalence of cases of penicillin-nonsusceptible S. pneumoniae * (PNSP) among invasive pneumococcal infections in selected metropolitan areas for 1995 is presented. In these areas, population-based active surveillance for all invasive pneumococcal infections is ongoing; in each of the regions, the denominator reflects greater than 100 cases of invasive pneumococcal disease. The prevalence of PNSP from hospital to hospital within each metropolitan area varied widely, suggesting that sentinel hospitals may not accurately reflect the prevalence of PNSP within a given city, let alone for the entire state. In addition, the prevalence of PNSP cases can increase rapidly (e.g., the prevalence of PNSP cases for Atlanta was 25% in 1994 and 33% in 1995).

Prevalence of PNSP among invasive Active surveillance area pneumococcal infections -------------------------------------------------------------------- - State of Connecticut ** 10%-19% Baltimore, MD Minneapolis/St. Paul, MN ** San Francisco, CA

Portland, OR ** 20%-29% San Antonio, TX

Atlanta, GA >= 30% Urban counties, TN ***


* S. pneumoniae isolates with penicillin minimum inhibitory concentration greater than or equal to 0.125 mg/mL. ** These figures are based on data from less than 1 year. *** Includes the metropolitan areas of Chattanooga, Knoxville, Memphis, and Nashville, Tennessee.

International Notes

Ebola Hemorrhagic Fever

In 1995, an outbreak of Ebola hemorrhagic fever (EHF) caused by the Zaire subtype of Ebola virus occurred in Kikwit, Zaire. A total of 316 cases of EHF were confirmed, resulting in 244 deaths (case-fatality rate: 77%). Case-patients ranged in age from 3 days to 71 years (median age: 35 years), and slightly more than half of the case-patients (i.e., 53%) were female. The earliest identified case occurred in January, and the epidemic peaked in May 1995. In December 1995, a single case of EHF occurred in Cote d'Ivoire and was caused by the recently recognized Ivory Coast subtype of Ebola virus. The natural reservoir of Ebola virus remains unknown.


PART 1: Summaries of Notifiable Diseases in the United States

EXPLANATION OF SYMBOLS USED IN TABLES, GRAPHS, AND MAPS Data not available ............................................. NA Report of disease is not required

in that jurisdiction (not notifiable) ............................................NN No reported cases ...............................................

Table_A NOTIFIABLE DISEASES -- Summary of reported cases, by month,

United States, 1995

Table_B1 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995

Table_B2 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995 (continued)

Table_B3 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995 (continued)

Table_B4 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995 (continued)

Table_B5 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995 (continued)

Table_B6 NOTIFIABLE DISEASES Reported cases, by geographic division

and area, United States, 1995 (continued)

Table_C NOTIFIABLE DISEASES -- Summary of reported cases, by age

group, United States, 1995


Table_D NOTIFIABLE DISEASES -- Summary of reported cases, by sex,

United States, 1995

Table_E NOTIFIABLE DISEASES -- Summary of reported cases, by race,

United States, 1995

Table_F NOTIFIABLE DISEASES -- Summary of reported cases, by

ethnicity, United States, 1995


PART 2: Graphs and Maps for Selected Notifiable Diseases in the United States

EXPLANATION OF SYMBOLS USED IN TABLES, GRAPHS, AND MAPS Data not available.............................................. NA Report of disease is not required

in that jurisdiction (not notifiable) ........................................... NN No reported cases ..............................................

Figure_1 ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) -- reported cases,

by quarter, United States, 1984-1995

Figure_2 ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) -- reported cases,

per 100,000 population, United States and Puerto Rico, 1995

Figure_3 ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) -- reported

pediatric cases, United States and Puerto Rico, 1995

Figure_4 ARBOVIRAL INFECTIONS (of the central nervous system) --

reported laboratory-confirmed cases caused by California serogroup viruses, by month of onset, United States, 1986 1995

Figure_5 ARBOVIRAL INFECTIONS (of the central nervous system) --

reported laboratory-confirmed cases caused by eastern equine encephalitis virus, by month of onset, United States, 1986 1995

Figure_6 ARBOVIRAL INFECTIONS (of the central nervous system) --

reported laboratory-confirmed cases caused by St. Louis encephalitis virus, by month of onset, United States, 1986 1995

Figure_7 ARBOVIRAL INFECTIONS (of the central nervous system) --

reported laboratory-confirmed cases caused by western equine encephalitis virus, by month of onset, United States, 1986 1995

Figure_8 BOTULISM (foodborne) -- by year, United States, 1975 1995

Figure_9 BOTULISM (infant) -- by year, United States, 1975 1995

Figure_10 BRUCELLOSIS -- by year, United States, 1965 1995

Figure_11 CHLAMYDIA -- reported cases among women, per 100,000

population, United States, 1995

Figure_12 CHOLERA -- reported cases, United States and territories,

1995

Figure_13 DIPHTHERIA -- by year, United States, 1965 1995

Figure_14 ESCHERICHIA COLI O157:H7 -- reported cases, United States

and territories, 1995

Figure_15 ESCHERICHIA COLI O157:H7 -- reported isolates, United

States, 1995

Figure_16 GONORRHEA -- reported cases, per 100,000 population, United

States, 1995

Figure_17 GONORRHEA -- by sex, United States, 1981 1995

Figure_18 GONORRHEA -- by race and ethnicity, United States, 1981 1995

Figure_19 HAEMOPHILUS INFLUENZAE, INVASIVE -- by age group, United

States, 1995

Figure_20 HANSEN DISEASE (LEPROSY) -- by year, United States,

1965 1995

Figure_21 HEPATITIS -- by year, United States, 1965 1995

Figure_22 HEPATITIS A -- reported cases, per 100,000 population,

United States and territories, 1995

Figure_23 HEPATITIS B -- reported cases, per 100,000 population,

United States and territories, 1995

Figure_24 LEGIONELLOSIS -- by year, United States, 1980 1995

Figure_25 LYME DISEASE -- reported cases, per 100,000 population,

United States and territories, 1995

Figure_26 MALARIA -- by year, United States, 1965 1995

Figure_27 MEASLES (rubeola) -- by year, United States, 1960 1995

Figure_28 MENINGOCOCCAL DISEASE -- by year, United States, 1965 1995

Figure_29 MUMPS -- by year, United States, 1968 1995

Figure_30 PERTUSSIS (whooping cough) -- by year, United States,

1965 1995

Figure_31 PERTUSSIS (whooping cough) -- by age group, United States,

1995

Figure_32 PLAGUE -- among humans, by year, United States, 1965 1995

Figure_33 POLIOMYELITIS (paralytic) -- by year, United States,

1965 1995

Figure_34 PSITTACOSIS -- by year, United States, 1965 1995

Figure_35 RABIES -- wild and domestic animals, by year, United States

and Puerto Rico, 1965 1995

Figure_36 ROCKY MOUNTAIN SPOTTED FEVER (RMSF) -- by year, United

States, 1965 1995

Figure_37 RUBELLA (German measles) -- by year, United States,

1966 1995

Figure_38 SALMONELLOSIS (excluding typhoid fever) -- by year, United

States, 1965 1995

Figure_39 SALMONELLA -- serotype of isolate by year, United States,

1970 1995

Figure_40 SHIGELLOSIS -- by year, United States, 1965 1995

Figure_41 SHIGELLA -- species of isolate by year, United States,

1970 1995

Figure_42 SYPHILIS (primary and secondary) -- reported cases, per

100,000 population, United States, 1995

Figure_43 SYPHILIS (primary and secondary) -- by sex, United States,

1981 1995

Figure_44 SYPHILIS (primary and secondary) -- by race, United States,

1981 1995

Figure_45 CONGENITAL SYPHILIS -- in infants <1 year of age, United

States, 1965 1995

Figure_46 TETANUS -- by year, United States, 1965 1995

Figure_47 TOXIC-SHOCK SYNDROME (TSS) -- by quarter, United States,

1980 1995

Figure_48 TRICHINOSIS -- by year, United States, 1965 1995

Figure_49 TUBERCULOSIS -- reported cases, per 100,000 population,

United States and territories, 1995

Figure_50 TUBERCULOSIS -- by year, United States, 1975 1995

Figure_51 TUBERCULOSIS -- by year, among persons born in the United

States and foreign-born persons, United States, 1986 1995

Figure_52 TYPHOID FEVER -- by year, United States, 1965 1995

Figure_53 VARICELLA (chickenpox) -- by month, United States, 1987 1995


PART 3: Historical Summary Tables

Table_1 TABLE 1. NOTIFIABLE DISEASES -- summary of reported cases,

per 100,000 population, United States, 1986-1995

Table_2 TABLE 2. NOTIFIABLE DISEASES -- summary of reported cases,

United States, 1988-1995

Table_3 TABLE 3. NOTIFIABLE DISEASES -- summary of reported cases,

United States, 1980-1987

Table_4 TABLE 4. NOTIFIABLE DISEASES -- summary of reported cases,

United States, 1972-1979

Table_5 TABLE 5. NOTIFIABLE DISEASES -- summary of reported cases,

United States, 1966-1971

Table_6 TABLE 6. NOTIFIABLE DISEASES -- deaths from selected diseases,

United States, 1984-1993. (Numbers in ICD column refer to the category numbers listed in the Ninth Revision of the International Classification of Diseases, 1994.)


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Chancroid

CDC. Chancroid in the United States, 1981-1990: evidence for underreporting

of cases. MMWR 1992;41(No. SS-3):57-61. CDC. Chancroid detected by polymerase chain reaction -- Jackson,

Mississippi, 1994-1995. MMWR 1995; 44:567,573-4. DiCarlo RP, Armentor BS, Martin DH. Chancroid epidemiology in New Orleans

men. J Infect Dis 1995;172:446-52.

Chlamydia trachomatis infection

CDC. Recommendations for the prevention and management of Chlamydia

trachomatis infections, 1993. MMWR 1993; 42(No. RR-12). Hillis SD, Nakashima A, Marchbanks PA, Addiss DG, Davis JP. Risk factors

for recurrent Chlamydia trachomatis infections in women. Am J Obstet Gynecol 1994;170:801-6. Hillis SD, Nakashima A, Amsterdam L, et al. The impact of a comprehensive

chlamydia prevention program in Wisconsin. Family Planning Perspectives 1995;27:108-11.

Cholera

Blake PA. Epidemiology of cholera in the Americas. Gastroenterol

Clin North Am 1993;22:639-60. Boyce TG, Mintz ED, Greene KD, et al. Vibrio cholerae O139 Bengal

infections among tourists to southeast Asia: an intercontinental foodborne outbreak. J Infect Dis 1995;172:1401-4. Wachsmuth IK, Blake PA, Olsvik O, eds. Vibrio cholerae and cholera:

molecular to global perspectives. Washington, DC: American Society for Microbiology, 1994. World Health Organization. Guidelines for cholera control. Geneva: World

Health Organization, 1993.

Congenital Syphilis

CDC. Guidelines for the prevention and control of congenital syphilis.

MMWR 1988; 37(No. S-1):1-13. CDC. Surveillance for geographic and secular trends in congenital

syphilis -- United States, 1983-1991. MMWR 1993; 42(No. SS-6):59-71. CDC. Evaluation of congenital syphilis surveillance system -- New Jersey,

1993. MMWR 1995; 44:225-7. Thompson BL, Matuszak D, Dwyer DM, Nakashima A, Pearce H, Israel E.

Congenital syphilis in Maryland, 1989-1991: the effect of changing the case definition and opportunities for prevention. Sex Transm Dis 1995; 22:364-9.

Cryptosporidiosis

CDC. Assessing the public health threat associated with waterborne

cryptosporidiosis: report of a workshop. MMWR 1995;44(No. RR-6). CDC. Surveillance for waterborne-disease outbreaks -- United States,

1993-1994. MMWR 1996;45(No. SS-1). Juranek DD. Cryptosporidiosis: sources of infection and guidelines for

prevention. Clin Infect Dis 1995;21(suppl 1):S57-61.

Diphtheria

CDC. Diphtheria acquired by U.S. citizens in the Russian Federation and

Ukraine -- 1994. MMWR 1995;44:237,243-4. Chen RT, Broome CV, Weinstein RA, Weaver R, Tsai TF. Diphtheria in the

United States, 1971-1981. Am J Public Health 1985;75:1393-7. Hardy IRB, Dittmann S, Sutter RW. Resurgence of diphtheria in the New

Independent States of the former Soviet Union: current situation and control strategies. Lancet 1996; (in press).

Escherichia coli O157:H7, Hemolytic-uremic syndrome

Bell BP, Goldoft M, Griffin PM, et al. A multistate outbreak of Escherichia

coli O157:H7-associated bloody diarrhea and hemolytic uremic syndrome from hamburgers: the Washington experience. JAMA 1994;272:1449-53. Boyce TG, Pemberton AG, Wells JG, Griffin PM. Screening for Escherichia

coli O157:H7 -- a national survey of clinical laboratories. J Clin Microbiol 1995;33:3275-7. Boyce TG, Swerdlow DL, Griffin PM. Escherichia coli O157:H7 and the

hemolytic-uremic syndrome. N Engl J Med 1995;333:364-8. Griffin PM, Tauxe RV. The epidemiology of infections caused by Escherichia

coli O157:H7, other enterohemorrhagic E.coli, and the associated hemolytic uremic syndrome. Epidemiol Rev 1991;13:60-98. Martin DL, MacDonald KL, White KE, Soler JT, Osterholm MT. The epidemiology

and clinical aspects of the hemolytic uremic syndrome in Minnesota. N Engl J Med 1990;323:1161-7.

Gonorrhea

CDC. Surveillance for gonorrhea and primary and secondary syphilis among

adolescents -- United States, 1981-1991. MMWR 1993;42(No. SS-3):1-11. CDC. Sentinel surveillance for antimicrobial resistance in Neisseria

gonorrhoeae -- United States, 1988-1991. MMWR 1993;42(No. SS-3):29-39. CDC. Increasing incidence of gonorrhea--Minnesota, 1994. MMWR 1995;44:

282-6. CDC. Fluoroquinolone resistance in Neisseria gonorrhoeae -- Colorado and

Washington, 1995. MMWR 1995;44:761-4.

Haemophilus influenzae, invasive

Adams WG, Deaver KA, Cochi SL, et al. Decline of childhood Haemophilus

influenzae type b (Hib) disease in the Hib vaccine era. JAMA 1993;269: 221-6. CDC. Recommendations for use of Haemophilus b conjugate vaccines and a

combined diphtheria, tetanus, pertussis, and Haemophilus b vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 1993;42(No. RR-13). CDC. Progress toward elimination of Haemophilus influenzae type b disease

among infants and children -- United States, 1993-1994. MMWR 1995;44: 545-50.

Hansen disease (Leprosy)

Mastro TD, Redd SC, Breiman RF. Imported leprosy in the United States, 1978

through 1988; an epidemic without secondary transmission. Am J Public Health 1992 Aug;82:1127-30. Noordeen SK. Epidemiology and control of leprosy -- a review of progress

over the last 30 years. Trans R Soc Trop Med Hyg 1993;87:515-7. Smith PG. Recent trends in the epidemiology of tuberculosis and leprosy.

Trop Geogr Med 1991 Jul;43:S22-9.

Hepatitis

Alter MJ, Mares A, Hadler SC, Maynard JE. The effect of underreporting on

the apparent incidence and epidemiology of acute viral hepatitis. Am J Epidemiol 1987;125:133-9. CDC. Hepatitis surveillance report no. 56. Atlanta: US Department of Health

and Human Services, Public Health Service, 1996.

Hepatitis A

Lemon SM, Shapiro CN. The value of immunization against hepatitis A. Infect

Agents and Dis 1994;1:38-49. Shapiro CN, Coleman PJ, McQuillan GM, et al. Epidemiology of hepatitis A:

seroepidemiology and risk groups in the U.S.A. Vaccine 1992;10(suppl 1):S59-62.

Hepatitis B

Margolis HS, Alter MJ, Hadler SC. Hepatitis B: evolving epidemiology and

implications for control. Semin Liver Dis 1991;11:84-92.

Hepatitis, C/Non-A, non-B

Alter MJ, Hadler SC, Judson FN, et al. Risk factors for acute non-A,

non-B hepatitis in the United States and association with hepatitis C virus infection. JAMA 1990;264:2231-5. Alter MJ, Margolis HS, Krawczynski K, et al. The natural history of

community-acquired hepatitis C in the United States. N Engl J Med 1992; 327:1899-905.

Legionellosis

Jernigan DB, Hofmann J, Cetron MS, et al. Outbreak of Legionnaires' disease

among cruise ship passengers exposed to a contaminated whirlpool spa. Lancet 1996;347:494-9. Keller DW, Hajjeh R, DeMaria A Jr, et al. Community outbreak of

Legionnaires' disease: an investigation confirming the potential for cooling towers to transmit Legionella species. Clin Infect Dis 1996;22: 257-61. Marston BJ, Lipman HB, Breiman RF. Surveillance for Legionnaires' disease:

risk factors for morbidity and mortality. Arch Intern Med 1994; 154: 2417-22. Miller LA, Beebe JL, Butler JC, et al. Use of polymerase chain reaction in

an epidemiologic investigation of Pontiac fever. J Infect Dis 1993;168: 769-72.

Lyme disease

CDC. Lyme disease -- United States, 1994. MMWR 1995;44:459-62. CDC. Recommendations for test performance and interpretation from the

Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR 1995;44:590-1. Dennis DT. Lyme Disease. Dermatol Clin 1995;13:537-51. Kalish R. Lyme disease. Rheum Dis Clin North Am 1993;19:399-426. Steere AC. Lyme disease. N Engl J Med 1989;321:586-96.

Malaria

CDC. Local transmission of Plasmodium vivax malaria -- Houston, Texas,

1994, MMWR 1994;44:295. Lobel HO, Miani M, Eng T, Bernard KW, Hightower AW, Campbell CC. Long-term

malaria prophylaxis with weekly mefloquine. Lancet 1993;341:848-51. Zucker JR, Campbell CC. Malaria: principles of prevention and treatment.

Infect Dis Clin North Am 1993;7:547-67.

Measles

CDC. Measles Prevention: recommendations of the Immunization Practices

Advisory Committee. MMWR 1989;38(No. SS-9). CDC. Measles -- United States, 1994. MMWR 1995;44:486-487, 493-494. CDC. Measles -- United States, 1995. MMWR 1996;45:305-307.

Meningococcal disease

CDC. Laboratory-based surveillance for meningococcal disease in selected

areas -- United States, 1989-1991. MMWR 1993;42(No. SS-2):21-30. CDC. Serogroup B meningococcal disease -- Oregon, 1994. MMWR 1995;44:121-4. Jackson LA, Schuchat A, Reeves MW, Wenger JD. Serogroup C meningococcal

outbreaks in the United States: an emerging threat. JAMA 1995;273: 383-9. Riedo FX, Plikaytis BD, Broome CV. Epidemiology and prevention of

meningococcal disease. Pediatr Infect Dis J 1995;14:643-57.

Mumps

Briss PA, Fehrs LJ, Parker RA, et al. Sustained transmission of mumps in a

highly vaccinated population: assessment of primary vaccine failure and waning vaccine-induced immunity. J Infect Dis 1994;169:77-82. CDC. Mumps prevention. MMWR 1989;38:388-92,397-400. CDC. Mumps Surveillance -- United States, 1988-1993. MMWR 1995;44(No.

SS-3):1-14. Hersch BS, Fine PEM, Kent WK, et al. Mumps outbreak in a highly vaccinated

population. J Pediatr 1991;119:187-93.

Pertussis

CDC. Pertussis -- United States, January 1992-June 1995. MMWR 1995;44:

525-9. Izurieta HS, Kenyon TA, Strebel PM, Baughman AL, Shulman ST, Wharton M.

Risk factors for pertussis in young infants during an outbreak in Chicago in 1993. Clin Infect Dis 1996;22:503-7. Wortis N, Strebel PM, Wharton M, Bardenheier B, Hardy IRB. Pertussis

deaths: report of 23 cases in the United States, 1992 and 1993. Pediatrics 1996;97:607-12.

Plague

Craven, RB, Barnes AM. Plague and tularemia. Infect Dis Clin North Am.

199l;5:165-75. Poland JD, Quan TJ, Barnes AM. Plague. In: Beran GW, ed. CRC handbook of

zoonoses. 2nd ed. Section A: bacterial, rickettsial, chlamydial, and mycotic. CRC Press, Inc., Boca Raton, Florida. 1994:93-112.

Poliomyelitis

CDC. Lack of evidence for wild poliovirus circulation -- United States,

1993. MMWR 1993;43:957-9. CDC. Progress toward global poliomyelitis eradication, 1985-1994. MMWR

1995;44:273-5, 281. Prevots DR, Sutter RW, Strebel PM, Weibel RE, Cochi SL. Completeness of

reporting for paralytic poliomyelitis, United States, 1980 through 1991. Arch Pediatr Adoles Med 1994;148:479-85. Strebel PM, Sutter RW, Cochi SL, et al. Epidemiology of poliomyelitis in

the United States: one decade after the last reported case of indigenous wild virus-associated disease. Clin Infect Dis 1992;14: 568-79.

Psittacosis

CDC. Human psittacosis linked to a bird distributor in Mississippi --

Massachusetts and Tennessee, 1992. MMWR 1992;41:794-7. Hedberg K, White KE, Forfang JC, et al. An outbreak of psittacosis in

Minnesota turkey industry workers: implications for modes of transmission and control. Am J Epidemiol 1989; 130:569-77. National Association of State Public Health Veterinarians. Compendium of

chlamydiosis (psittacosis) control, 1995. JAVMA 1995;206:1874-9. Wong KH, Skelton SK, Daugharty H. Utility of complement fixation and

microimmunofluorescence assays for detecting serologic responses in patients with clinically diagnosed psittacosis. J Clin Microbiol 1994; 32:2417-21.

Rabies

CDC. Rabies prevention -- United States. 1991: recommendations of the

Immunization Practices Advisory Committee (ACIP). MMWR 1991;40 (No. RR-3). CDC. Compendium of animal rabies control, 1995. MMWR 1995;44(No. RR-2). Krebs JW, Strine TW, Smith JS, Rupprecht CE, Childs JE. Rabies surveillance

in the United States during 1994. JAVMA 1995;207:1562-75.

Rocky Mountain spotted fever (RMSF)

Dalton MJ, Clarke MJ, Holman RC, et al. National surveillance for Rocky

Mountain spotted fever, 1981-1992, epidemiologic summary and evaluation of risk factors for fatal outcome. Am J Trop Med Hyg 1995;52(5):405-13. McDade JE, Fishbein DB. Rickettsiaceae: the rickettsiae. In: Laboratory

diagnosis of infectious diseases: principles and practice. Vol II. Viral, rickettsial, and chlamydial diseases. New York: Springer-Verlag, 1988:864-89.

Rubella

CDC. Rubella prevention: recommendations of the Immunization Practices

Advisory Committee (ACIP). MMWR 1990;39(No. RR-15). CDC. Outbreaks of rubella among the Amish -- United States, 1991. MMWR

1991;40:264. CDC. Rubella and congenital rubella syndrome -- United States, January 1,

1991-May 7, 1994. MMWR 1994;43:391,397-401. Lindegren ML, Fehrs LJ, Hadler SC, Hinman AR. Update: rubella and

congenital rubella syndrome, 1980-1990. Epidemiol Rev 1991;13:341-8.

Salmonellosis

CDC. Reptile-associated Salmonellosis -- selected states, 1994-1995. MMWR

1995;44:347-50. Hennessy TW, Hedberg CW, Slutsker L, et al. A national outbreak of

Salmonella Enteritidis infections from ice cream. N Engl J Med 1996; 334:1281-6. Lee LA, Puhr ND, Maloney EK, Bean NH, Tauxe RV. Increase in antimicrobial-

resistant Salmonella infections in the United States, 1989-1990. J Infect Dis 1994;170:128-34. Mishu B, Koehler J, Lee LA, et al. Outbreaks of Salmonella enteritidis

infections in the United States, 1985-1991. J Infect Dis 1994;169: 547-52. Tauxe RV. Salmonella: a postmodern pathogen. Journal of Food Protection

1991;54:563-8.

Shigellosis

Lee LA, Shapiro CN, Hargrett-Bean N, Tauxe RV. Hyperendemic shigellosis in

the United States: a review of surveillance data for 1967-1988. J Infect Dis 1991;164:894-900. Mohle-Boetani JC, Stapleton M, Finger R, et al. Communitywide shigellosis:

control of an outbreak and risk factors in child day-care centers. Am J Public Health 1995;85:812-16. Parsonnet J, Greene KD, Gerber AR, et al. Shigella dysenteriae type 1

infections in U.S. travelers to Mexico. Lancet 1989:543-5. Ries AA, Wells JG, Olivola D, et al. Epidemic Shigella dysenteriae type 1

in Burundi: panresistance and implications for prevention. J Infect Dis 1994;169:1035-41.

Syphilis

CDC. Outbreak of primary and secondary syphilis -- Baltimore City,

Maryland, 1995. MMWR 1996;45:166-9. Nakashima AK, Rolfs RT, Flock ML, Kilmarx P, Greenspan JR. Epidemiology of

syphilis in the United States, 1941-1993. Sex Transm Dis 1996;23:16-23. St.Louis ME, Farley TA, Aral SO. Untangling the persistence of syphilis in

the south. Sex Transm Dis 1996;23:1-4. Thomas JC, Kulik AL, Schoenbach VJ. Syphilis in the South: rural rates

surpass urban rates in North Carolina. Am J Public Health 1995;85: 1119-22.

Tetanus

Gergen PJ, McQuillan GM, Kiely M, et al. A population-based survey of

immunity to tetanus in the United States. N Engl J Med 1995;332:761-6. Prevots R, Sutter RW, Strebel PM, Cochi SL, Hadler S. Tetanus

surveillance -- United States, 1989-1990. MMWR 1992;41(No. SS-8):1-9. Sutter RW, Cochi SL, Brink EW, Sirotkin BI. Assessment of vital statistics

and surveillance data for monitoring tetanus mortality, United States, 1979-1984. Am J Epidemiol 1990;131:132-42.

Toxic-shock syndrome

CDC. Reduced incidence of menstrual toxic shock syndrome -- United States,

1980-1990. MMWR 1990;39:421-3. Gaventa S, Reingold AL, Hightower AW, et al. Active surveillance for toxic

shock syndrome in the United States, 1986. Rev Infect Dis 1989;(suppl): S28-34. Schuchat A, Broome CV. Toxic shock syndrome and tampons. Epidemiol Rev

1991;13:99-112.

Trichinosis

Bailey TM, Schantz PM. Trends in the incidence and transmission patterns of

human trichinosis in the United States, 1982-1986. Rev Infect Dis 1990; 12:5-11. CDC. Trichinosis surveillance -- United States, 1987-1990. MMWR 1991;40

(No. SS-3):35-42. McAuley JB, Michelson MK, Hightower AW, Engeran S, Wintermeyer LA, Schantz

PM. A trichinosis outbreak among Southeast Asian refugees. Am J Epidemiol 1992;135:1404-10.

Tuberculosis

American Thoracic Society/CDC. Treatment of tuberculosis and tuberculosis

infection in adults and children. Am J Respir Crit Care Med 1994;149: 1359-74. CDC. Recommendations for counting reported tuberculosis cases. Atlanta:

Us Department of Health and Human Services, Public Health Service, 1977.

Typhoid fever

CDC. Typhoid immunization: recommendations of the Advisory Committee on

Immunization Practices. MMWR 1994;43(No. RR-14). Ryan CA, Hargrett-Bean NT, Blake PA. Salmonella typhi infections in the

United States, 1975-1984: increasing role of foreign travel. Rev Infect Dis 1989;11:1-8. Woodruff BA, Pavia AT, Blake PA. A new look at typhoid vaccination:

information for the practicing physician. JAMA 1991;265:756-9.

Varicella

CDC. Varicella outbreak in a women's prison -- Kentucky. MMWR 1989;38:

635-6,641-2. CDC. Prevention of varicella: recommendations of the Advisory Committee on

Immunization Practices (ACIP). MMWR 1996;45(No. RR-11). Gershon AA, LaRussa P, Hardy I, Steinberg S, Silverstein S. Varicella

vaccine: the American experience. J Infect Dis 1992;166(suppl 1):S63-8. Lieu TA, Cochi SL, Black SB, et al. Cost-effectiveness of a routine

varicella vaccination program for U.S. children. JAMA 1994;271:375-81.
Table_A
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NOTIFIABLE DISEASES -- Summary of reported cases, by month, United States, 1995
=================================================================================================================================================================================
NAME                                Total     Jan.       Feb.     Mar.      Apr.       May     June    July      Aug.   Sept.     Oct.      Nov.     Dec.   Unk.
----------------------------------------------------------------------------------------------------------------------------------------------------------------
AIDS *                             71,547    5,499      5,551    8,455     4,741     5,418    5,765   6,797     5,104   7,291    5,160     6,002    5,764      -
Botulism, total                        97        2          3        6         7         6        3       9        10      17        9         7       18      -
Brucellosis                            98        3          3        1        10         9       15       6         8       7        6         2       28      -
Chancroid +                           606   ..............142.........    .............145.........   ............184........    ............135.........      -
Chlamydia +&                      477,638   ..........120,549.........    .........118,618.........   ........116,793........    ........121,768.........      -
Cholera                                23        2          -        -         2         5        3       5         -       2        1         2        1      -
Escherichia coli O157:H7            2,139       50         69       62        65        73      138     263       289     381      256       215      278      -
Gonorrhea +                       392,848   ..........102,600.........    ..........93,238.........   ........100,910........    .........96,100.........      -
Haemophilus influenzae, invasive    1,180      105        103      106       127        94       68     111        66      79       80        73      168      -
Hansen disease (leprosy)              144        9          7       10        17        19       15      15         8      12        8         3       21      -
Hepatitis A                        31,582    1,449      2,100    2,245     2,690     2,129    2,246   3,047     2,568   3,414    2,891     2,498    4,305      -
Hepatitis B                        10,805      466        707      837     1,046       864      799   1,012       763     884      829       744    1,854      -
Hepatitis, C/non-A non-B            4,576      144        440      314       448       263      290     360       317     357      392       292      959      -
Legionellosis                       1,241       67         70       93       133       104       76     148        84     111       90        59      206      -
Lyme disease                       11,700      207        424      435       394       492      742   2,385     1,878   1,421    1,041       868    1,413      -
Malaria                             1,419       52         95       74        80        95       97     164       121     187      155        84      215      -
Measles (rubeola)                     309       22         26      108        29        17       30      16        14       9       11        10       17      -
Meningococcal disease               3,243      225        278      339       357       314      219     253       149     157      223       161      568      -
Mumps                                 906       51         52       85        86       124       81      59        36      63       70        69      130      -
Pertussis (whooping cough)          5,137      195        216      212       275       200      220     538       534     795      458       430    1,064      -
Plague                                  9        -          -        -         2         -        2       1         -       2        2         -        -      -
Poliomyelitis, paralytic @              2        -          2        -         -         -        -       -         -       -        -         -        -      -
Psittacosis                            64        4          2        5         7         6        9       4         4       1        6         7        9      -
Rabies, animal                      7,811      436        417      716       754       572      614   1,090       574     720      695       451      772      -
Rabies, human                           5        -          -        1         -         -        -       -         -       1        1         -        2      -
Rocky Mountain spotted fever          590        8         10        7        14        30       56     103       103     110       57        26       66      -
Rubella (German measles)              128        9          4        3         9        10       17      35        17       2        3         7       12      -
Rubella, congenital syndrome            6        2          1        -         1         -        1       -         -       -        -         -        1      -
Salmonellosis                      45,970    1,716      2,142    1,947     2,584     2,757    3,242   5,146     4,675   6,282    5,408     3,976    6,095      -
Shigellosis                        32,080    1,335      2,015    1,833     2,112     2,022    2,093   3,115     2,773   3,918    3,676     2,504    4,684      -
Syphilis, total all stages +       68,953   ...........17,396.........    ..........18,065.........   .........18,150........    .........15,342.........      -
  Primary and secondary +          16,500   ............4,332.........    ...........4,030.........   ..........4,325........    ..........3,813.........      -
  Congenital <1 year **             1,548      192        176      178       150       120      148     124       102     104      109        78       67      -
Tetanus                                41        1          1        3         3         1        2       3         4       4        3         6       10      -
Toxic-shock syndrome                  191        9         21       17        19        15        9      18         9      18       13        10       33      -
Trichinosis                            29        -          2        6         8         1        2       2         2       1        2         1        2      -
Tuberculosis ++                    22,860      632      1,343    1,827     1,871     1,957    2,065   1,936     2,036   1,909    1,886     1,559    3,839      -
Typhoid fever                         369       16         27       32        33        35       21      31        20      53       32        33       36      -
Varicella (chickenpox) &&         120,624   12,488     15,502   17,503    19,957    16,712   11,242   7,195       907   1,923    2,447     4,300   10,448      -
----------------------------------------------------------------------------------------------------------------------------------------------------------------
 * The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases reported to the Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB
   Prevention (NCHSTP) through December 31, 1995.
 + Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996.
 & Chlamydia refers to genital infections caused by C. trachomatis.
 @ Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation of these cases is pending review by an external panel.
** For congenital syphilis only, cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of August 26, 1996.
++ Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
&& Not nationally notifiable.
=================================================================================================================================================================================

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Table_B1
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NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995
===============================================================================================================================
                     Total resident                   Botulism
                       population                -------------------
Area                 (in thousands)    AIDS *    Foodborne    Infant    Brucellosis    Chancroid +
--------------------------------------------------------------------------------------------------
United States           262,755        71,547       24          54           98            606

New England              13,312         3,608        1           -            1              7
  Maine                   1,241           130        -           -            -              -
  N.H.                    1,148           112        -           -            -              -
  Vt.                       585            44        -           -            -              -
  Mass.                   6,074         1,447        1           -            -              7
  R.I.                      990           223        -           -            -              -
  Conn.                   3,275         1,652        -           -            1              -

Mid. Atlantic            38,153        19,185        -          16            2            340
  N.Y. (excl. NYC)       10,824         2,364        -           1            -              2
  N.Y.C.                  7,312        10,035        -           -            1            334
  N.J.                    7,945         4,409        -           7            -              4
  Pa.                    12,072         2,377        -           8            1              -

E.N. Central             43,456         5,410        -           5           12             29
  Ohio                   11,151         1,110        -           2            -              5
  Ind.                    5,803           529        -           -            -              -
  Ill.                   11,830         2,220        -           -            8             21
  Mich.                   9,549         1,201        -           1            3              -
  Wis.                    5,123           350        -           2            1              3

W.N. Central             18,348         1,734        1           -            4              2
  Minn.                   4,610           369        -           -            2              -
  Iowa                    2,842           116        -           -            2              -
  Mo.                     5,324           791        -           -            -              -
  N. Dak.                   641             5        -           -            -              -
  S. Dak.                   729            19        -           -            -              -
  Nebr.                   1,637           114        -           -            -              -
  Kans.                   2,565           320        1           -            -              2

S. Atlantic              46,995        17,983        1           4            9             47
  Del.                      717           316        -           1            -              -
  Md.                     5,042         2,575        -           1            2              -
  D.C.                      554         1,029        -           -            -              -
  Va.                     6,618         1,610        1           2            -              2
  W. Va.                  1,828           127        -           -            -              1
  N.C.                    7,195         1,000        -           -            3             18
  S.C.                    3,673           976        -           -            1              -
  Ga.                     7,201         2,291        -           -            1              2
  Fla.                   14,166         8,059        -           -            2             24

E.S. Central             16,066         2,279        -           1            3              9
  Ky.                     3,860           298        -           1            -              -
  Tenn.                   5,256           897        -           -            -              2
  Ala.                    4,253           642        -           -            -              7
  Miss.                   2,697           442        -           -            3              -

W.S. Central             28,828         6,136        -           1           24            156
  Ark.                    2,484           277        -           -            4              1
  La.                     4,342         1,087        -           1            -            129
  Okla.                   3,278           295        -           -            1              -
  Tex.                   18,724         4,477        -           -           19             26

Mountain                 15,645         2,263        7           2           13              4
  Mont.                     870            25        -           -            1              -
  Idaho                   1,163            49        4           -            -              -
  Wyo.                      480            17        -           -            2              -
  Colo.                   3,747           673        1           -            1              -
  N. Mex.                 1,685           164        -           -            4              -
  Ariz.                   4,218           678        2           -            5              2
  Utah                    1,951           164        -           2            -              -
  Nev.                    1,530           493        -           -            -              2

Pacific                  41,951        12,813       14          25           30             12
  Wash.                   5,431           892        6           -            -              5
  Oreg.                   3,141           459        -           -            1              -
  Calif.                 31,589        11,134        3          23           29              7
  Alaska                    604            69        5           -            -              -
  Hawaii                  1,187           259        -           2            -              -

  Guam                      133             -        -           -            -              -
  P.R.                    3,522         2,594        -           -            -              1
  V.I.                      102            39        -           -            -              2
  C.N.M.I.                   43             -        -           -            -             NA
  American Samoa             47             -       NA          NA           NA             NA
--------------------------------------------------------------------------------------------------
* The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases                NA: Not Available
  reported to the Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB Prevention       -: No reported cases
  (NCHSTP) through December 31, 1995. This total includes 136 cases in persons
  whose state of residence is unknown.
+ Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996.
===============================================================================================================================

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Table_C
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NOTIFIABLE DISEASES -- Summary of reported cases, by age group, *
United States, 1995
===========================================================================================================================================================================================
                                                          Age
                                                          not
NAME                                    Total        <5     (Rate)     5-14      (Rate)      15-24      (Rate)      25-44      (Rate)     45-64     (Rate)       65+     (Rate)    stated
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
AIDS +                                  71,547       555    ( 2.82)      264     ( 0.71)      2,666    (  7.51)     53,460    ( 65.29)    13,764    (27.78)       838    ( 2.56)       -
Botulism, total                             97        56    ( 0.28)        4     ( 0.01)          2    (  0.01)         20    (  0.02)        12    ( 0.02)         1    ( 0.00)       2
Brucellosis                                 98         4    ( 0.02)       11     ( 0.03)         17    (  0.05)         44    (  0.05)        13    ( 0.03)         9    ( 0.03)       -
Cholera                                     23         3    ( 0.02)        -     (  -  )          1    (  0.00)          4    (  0.00)        11    ( 0.02)         3    ( 0.01)       1
Escherichia coli O157:H7                 2,139       444    ( 2.73)      503     ( 1.66)        264    (  0.91)        314    (  0.47)       290    ( 0.72)       266    ( 1.00)      58
Gonorrhea&                             395,493         -    (  -  )    8,076     (21.80)    228,698    (645.01)    132,988    (162.41)    11,046    (22.29)     3,457    (10.54)   9,271
Haemophilus influenzae, invasive         1,180       290    ( 1.47)       66     ( 0.18)         41    (  0.12)        135    (  0.16)       203    ( 0.41)       427    ( 1.30)      18
Hansen disease (leprosy)                   144         -    (  -  )        4     ( 0.01)         19    (  0.05)         40    (  0.05)        36    ( 0.07)        25    ( 0.08)      20
Hepatitis A                             31,582     2,053    (10.42)    6,666     (17.99)      6,382    ( 18.00)     12,160    ( 14.85)     2,801    ( 5.65)     1,042    ( 3.18)     478
Hepatitis B                             10,805        81    ( 0.42)      212     ( 0.58)      2,060    (  5.88)      6,018    (  7.42)     1,707    ( 3.48)       441    ( 1.36)     286
Hepatitis, C/non-A non-B                 4,576        50    ( 0.26)       32     ( 0.09)        264    (  0.75)      2,973    (  3.66)       920    ( 1.88)       251    ( 0.77)      86
Legionellosis                            1,241         4    ( 0.02)       10     ( 0.03)         30    (  0.09)        255    (  0.32)       397    ( 0.81)       518    ( 1.60)      27
Lyme disease                            11,700       699    ( 3.55)    1,997     ( 5.39)        994    (  2.80)      3,213    (  3.92)     3,043    ( 6.14)     1,608    ( 4.90)     146
Malaria                                  1,419        88    ( 0.45)      145     ( 0.39)        247    (  0.70)        596    (  0.73)       224    ( 0.45)        58    ( 0.18)      61
Measles (rubeola)                          309       107    ( 0.54)       48     ( 0.13)         45    (  0.13)         74    (  0.09)        16    ( 0.03)         -    (  -  )      19
Meningococcal disease                    3,243     1,093    ( 5.55)      518     ( 1.40)        606    (  1.71)        347    (  0.42)       299    ( 0.60)       346    ( 1.06)      34
Mumps                                      906       165    ( 0.85)      418     ( 1.15)        117    (  0.34)        138    (  0.17)        41    ( 0.08)         6    ( 0.02)      21
Pertussis (whooping cough)               5,137     2,733    (13.87)    1,246     ( 3.36)        405    (  1.14)        516    (  0.63)       160    ( 0.32)        41    ( 0.13)      36
Plague                                       9         -    (  -  )        1     ( 0.00)          1    (  0.00)          4    (  0.00)         2    ( 0.00)         1    ( 0.00)       -
Poliomyelitis, paralytic @                   2         2    ( 0.01)        -     (  -  )          -    (   -  )          -    (   -  )         -    (  -  )         -    (  -  )       -
Psittacosis                                 64         2    ( 0.01)        1     ( 0.00)          8    (  0.02)         27    (  0.03)        20    ( 0.04)         3    ( 0.01)       3
Rabies, human                                5         1    ( 0.01)        1     ( 0.00)          -    (   -  )          2    (  0.00)         -    (  -  )         1    ( 0.00)       -
Rocky Mountain spotted fever               590        47    ( 0.24)      112     ( 0.30)         60    (  0.17)        206    (  0.25)       109    ( 0.22)        49    ( 0.15)       7
Rubella (German measles)                   128         9    ( 0.05)       10     ( 0.03)         26    (  0.07)         66    (  0.08)        14    ( 0.03)         1    ( 0.00)       2
Salmonellosis                           45,970    12,177    (61.80)    4,477     (12.08)      4,002    ( 11.29)      9,145    ( 11.17)     4,701    ( 9.49)     3,978    (12.13)   7,490
Shigellosis                             32,080     9,130    (46.33)    7,428     (20.05)      2,369    (  6.68)      5,074    (  6.20)     1,364    ( 2.75)       639    ( 1.95)   6,076
Syphilis, primary and secondary &       16,501         -    (  -  )      114     ( 0.31)      4,860    ( 13.71)      9,647    ( 11.78)     1,655    ( 3.34)       187    ( 0.57)      11
Tetanus                                     41         2    ( 0.01)        1     ( 0.00)          2    (  0.01)         20    (  0.02)         6    ( 0.01)        10    ( 0.03)       -
Toxic-shock syndrome                       191         8    ( 0.04)       33     ( 0.09)         39    (  0.11)         74    (  0.09)        23    ( 0.05)         7    ( 0.02)       7
Trichinosis                                 29         1    ( 0.01)        -     (  -  )          2    (  0.01)         14    (  0.02)         8    ( 0.02)         3    ( 0.01)       1
Tuberculosis **                         22,860       783    ( 3.97)      645     ( 1.74)      1,703    (  4.80)      8,241    ( 10.06)     5,998    (12.10)     5,337    (16.28)     153
Typhoid fever                              369        43    ( 0.22)       78     ( 0.21)         84    (  0.24)        132    (  0.16)        19    ( 0.04)        12    ( 0.04)       1
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
 * July 1, 1993, post-censal population estimates were used to calculate incidence rates per 100,000 population.
 + The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases reported to the Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB
   Prevention (NCHSTP) through December 31, 1995.
 & Age-related data are collected on aggregate forms different from those used for the number of reported cases. Therefore, the total cases reported on this table may differ slightly
   from other tables. Cases among persons ages <5 years are not shown because some of these may not be caused by sexual transmission; these cases are, however, included in
   the totals. Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996. Age data for 1995 are unavailable for chancroid
   and chlamydia.
 @ Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation of these cases is pending review by an external panel.
** Casese were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
===========================================================================================================================================================================================

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Table_D
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NOTIFIABLE DISEASES -- Summary of reported cases, by sex, * United States, 1995
=================================================================================================================================
                                                                                             Sex
                                                                                             not
NAME                                 Total       Male      (Rate)     Female       (Rate)   stated
--------------------------------------------------------------------------------------------------
AIDS +                               71,547     58,007    ( 46.56)     13,540     ( 10.27)      -
Botulism, total                          97         46    (  0.04)         51     (  0.04)      -
Brucellosis                              98         59    (  0.05)         39     (  0.03)      -
Chancroid &                             606        443    (  0.35)        160     (  0.12)      3
Chlamydia &@                        477,638          -    (   -  )    383,956     (290.29)      1
Cholera                                  23          9    (  0.01)         13     (  0.01)      1
Escherichia coli O157:H7              2,139        970    (  0.95)      1,144     (  1.06)     25
Gonorrhea &                         392,848    203,563    (158.64)    188,650     (140.32)    635
Haemophilus influenzae, invasive      1,180        575    (  0.46)        602     (  0.46)      3
Hansen disease (leprosy)                144         85    (  0.07)         40     (  0.03)     19
Hepatitis A                          31,582     17,488    ( 14.04)     13,943     ( 10.58)    151
Hepatitis B                          10,805      6,448    (  5.23)      4,286     (  3.29)     71
Hepatitis, C/non-A non-B              4,576      2,848    (  2.31)      1,696     (  1.30)     32
Legionellosis                         1,241        706    (  0.57)        529     (  0.41)      6
Lyme disease                         11,700      5,890    (  4.73)      5,772     (  4.38)     38
Malaria                               1,419        863    (  0.69)        519     (  0.39)     37
Measles (rubeola)                       309        133    (  0.11)        154     (  0.12)     22
Meningococcal disease                 3,243      1,688    (  1.35)      1,542     (  1.17)     13
Mumps                                   906        480    (  0.39)        411     (  0.32)     15
Pertussis (whooping cough)            5,137      2,421    (  1.94)      2,707     (  2.05)      9
Plague                                    9          4    (  0.00)          5     (  0.00)      -
Poliomyelitis, paralytic **               2          2    (  0.00)          -     (   -  )      -
Psittacosis                              64         28    (  0.02)         36     (  0.03)      -
Rabies, human                             5          3    (  0.00)          2     (  0.00)      -
Rocky Mountain spotted fever            590        322    (  0.26)        266     (  0.20)      2
Rubella (German measles)                128         63    (  0.05)         63     (  0.05)      2
Rubella, congenital syndrome              6          2    (  0.00)          4     (  0.00)      -
Salmonellosis                        45,970     19,093    ( 15.32)     20,084     ( 15.23)  6,793
Shigellosis                          32,080     11,955    (  9.60)     14,523     ( 11.02)  5,602
Syphilis, primary and secondary &    16,500      8,731    (  6.80)      7,768     (  5.78)      1
Tetanus                                  41         27    (  0.02)         14     (  0.01)      -
Toxic-shock syndrome                    191         54    (  0.04)        131     (  0.10)      6
Trichinosis                              29         19    (  0.02)          9     (  0.01)      1
Tuberculosis ++                      22,860     14,494    ( 11.63)      8,348     (  6.33)     18
Typhoid fever                           369        207    (  0.17)        160     (  0.12)      2
--------------------------------------------------------------------------------------------------
 * July 1, 1993, post-censal population estimates were used to calculate rates. Rates are reported per 100,000 population.
 + The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases reported to the Division of HIV/AIDS
   Prevention, National Center for HIV, STD, and TB Prevention (NCHSTP) through December 31, 1995.
 & Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996.
 @ Chlamydia refers to genital infections caused by C. trachomatis. The rates for men are not presented, as reporting on men is
   much more limited than on women.
** Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation of these cases is pending
   review by an external panel.
++ Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
=================================================================================================================================

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Table_E
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NOTIFIABLE DISEASES -- Summary of reported cases, by race, United States, 1995
===================================================================================================================================================================================
                                               American Indian          Asian or
                                                     or                 Pacific                                                                Race not
Name                                  Total     Alaskan Native   (%)    Islander   (%)      Black    (%)     White     (%)     Other   (%)      stated     (%)
---------------------------------------------------------------------------------------------------------------------------------------------------------------
AIDS *                                71,547          238        (<1)      556     ( 1)     29,326   (41)    29,715   ( 42)      -     ( -)      11,712 +  (16)
Botulism, total                           97            5        ( 5)        7     ( 7)          -   ( -)        53   ( 55)      -     ( -)          32    (33)
Brucellosis                               98            -        ( -)        -     ( -)          4   ( 4)        50   ( 51)      -     ( -)          44    (45)
Cholera                                   23            -        ( -)        2     ( 9)          -   ( -)        10   ( 43)      -     ( -)          11    (48)
Escherichia coli O157:H7               2,139            2        (<1)       18     ( 1)         62   ( 3)     1,224   ( 57)      4     (<1)         829    (39)
Gonorrhea &                          395,493        1,472        (<1)    1,305     (<1)    240,887   (61)    42,198   ( 11)      -     ( -)    109,631+    (28)
Haemophilus influenzae, invasive       1,180           15        ( 1)       15     ( 1)        144   (12)       766   ( 65)      3     (<1)         237    (20)
Hansen disease (leprosy)                 144            -        ( -)       43     (30)          7   ( 5)        39   ( 27)      1     ( 1)          54    (38)
Hepatitis A                           31,582        1,375        ( 4)      428     ( 1)      3,066   (10)    18,967   ( 60)     61     (<1)       7,685    (24)
Hepatitis B                           10,805          100        ( 1)      710     ( 7)      2,394   (22)     4,772   ( 44)     25     (<1)       2,804    (26)
Hepatitis, C/non-A non-B               4,576           45        ( 1)       38     ( 1)        542   (12)     1,798   ( 39)      3     (<1)       2,150    (47)
Legionellosis                          1,241            2        (<1)       10     ( 1)        108   ( 9)       852   ( 69)      2     (<1)         267    (22)
Lyme disease                          11,700           22        (<1)       83     ( 1)        204   ( 2)     8,945   ( 76)      -     ( -)       2,446    (21)
Malaria                                1,419            5        (<1)      225     (16)        444   (31)       367   ( 26)     28     ( 2)         350    (25)
Measles (rubeola)                        309            8        ( 3)       10     ( 3)         13   ( 4)       170   ( 55)      -     ( -)         108    (35)
Meningococcal disease                  3,243           42        ( 1)       29     ( 1)        503   (16)     2,152   ( 66)      4     (<1)         513    (16)
Mumps                                    906            8        ( 1)       33     ( 4)         73   ( 8)       403   ( 44)      3     (<1)         386    (43)
Pertussis (whooping cough)             5,137           55        ( 1)       62     ( 1)        314   ( 6)     2,780   ( 54)      2     (<1)       1,924    (37)
Plague                                     9            2        (22)        -     ( -)          -   ( -)         6   ( 67)      -     ( -)           1    (11)
Poliomyelitis, paralytic @                 2            -        ( -)        -     ( -)          -   ( -)         2   (100)      -     ( -)           -    ( -)
Psittacosis                               64            -        ( -)        -     ( -)          2   ( 3)        40   ( 63)      -     ( -)          22    (34)
Rabies, human                              5            -        ( -)        -     ( -)          -   ( -)         4   ( 80)      -     ( -)           1    (20)
Rocky Mountain spotted fever             590           11        ( 2)        4     ( 1)         33   ( 6)       450   ( 76)      -     ( -)          92    (16)
Rubella (German measles)                 128            -        ( -)       10     ( 8)          7   ( 5)        87   ( 68)      -     ( -)          24    (19)
Rubella, congenital syndrome               6            -        ( -)        -     ( -)          -   ( -)         2   ( 33)      -     ( -)           4    (67)
Salmonellosis                         45,970          217        (<1)      686     ( 1)      3,817   ( 8)    20,875   ( 45)     34     (<1)      20,341    (44)
Shigellosis                           32,080        2,031        ( 6)      166     ( 1)      4,153   (13)    12,828   ( 40)     13     (<1)     12,889+    (40)
Syphilis, primary and secondary &     16,501           47        (<1)       54     (<1)     13,974   (85)     1,487   (  9)      -     ( -)         939    ( 6)
Tetanus                                   41            1        ( 2)        1     ( 2)          1   ( 2)        31   ( 76)      -     ( -)           7    (17)
Toxic-shock syndrome                     191            1        ( 1)        3     ( 2)         12   ( 6)       140   ( 73)      -     ( -)          35    (18)
Trichinosis                               29            -        ( -)        -     ( -)          -   ( -)        10   ( 34)      -     ( -)          19    (66)
Tuberculosis **                       22,860          327        ( 1)    4,035     (18)      7,766   (34)    10,606   ( 46)      -     ( -)         126    ( 1)
Typhoid fever                            369            2        ( 1)      107     (29)         32   ( 9)        71   ( 19)     12     ( 3)         145    (39)
---------------------------------------------------------------------------------------------------------------------------------------------------------------
 * The total number of acquired immunodeficiency syndrome (AIDS) includes all cases reported through December 31, 1995.
 + Includes cases originally reported as Hispanic: 11,577 for AIDS; 16,447 for gonorrhea; and 686 for syphilis, primary and secondary.
 & Race data are collected on aggregate forms different from those used for numbers of reported cases. Thus, the total number of cases reported on this table may differ slightly
   from other tables. Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996. Race data for 1995 are unavailable for
   chancroid and chlamydia.
 @ Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation of these cases is pending review by an external panel.
** Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
===================================================================================================================================================================================

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Table_F
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NOTIFIABLE DISEASES -- Summary of reported cases, by ethnicity, United States, 1995
======================================================================================================================================
                                                                                         Ethnicity
                                                                                            not
NAME                                Total     Hispanic    (%)    Non-Hispanic   (%)       stated      (%)
----------------------------------------------------------------------------------------------------------
AIDS *                              71,547     11,577     (16)      59,041      (83)         929 +   (  1)
Botulism, total                         97         14     (14)          53      (55)          30     ( 31)
Brucellosis                             98         57     (58)          23      (23)          18     ( 18)
Cholera                                 23         14     (61)           7      (30)           2     (  9)
Escherichia coli O157:H7             2,139         50     ( 2)       1,090      (51)         999     ( 47)
Gonorrhea &                        395,493     16,447     ( 4)     283,085      (72)      95,961 +   ( 24)
Haemophilus influenzae               1,180         70     ( 6)         710      (60)         400     ( 34)
Hansen disease (leprosy)               144         42     (29)          68      (47)          34     ( 24)
Hepatitis A                         31,582      5,051     (16)      17,473      (55)       9,058     ( 29)
Hepatitis B                         10,805      1,074     (10)       5,767      (53)       3,964     ( 37)
Hepatitis, C/non-A non-B             4,576        281     ( 6)       1,829      (40)       2,466     ( 54)
 Legionellosis                       1,241         21     ( 2)         717      (58)         503     ( 41)
Lyme disease                        11,700        200     ( 2)       6,129      (52)       5,371     ( 46)
Malaria                              1,419        126     ( 9)         856      (60)         437     ( 31)
Measles (rubeola)                      309         56     (18)         147      (48)         106     ( 34)
Meningococcal disease                3,243        343     (11)       1,995      (62)         905     ( 28)
Mumps                                  906        139     (15)         343      (38)         424     ( 47)
Pertussis (whooping cough)           5,137        376     ( 7)       2,366      (46)       2,395     ( 47)
Plague                                   9          1     (11)           7      (78)           1     ( 11)
Poliomyelitis, paralytic @               2          -     ( -)           -      ( -)           2     (100)
Psittacosis                             64          2     ( 3)          40      (63)          22     ( 34)
Rabies, human                            5          2     (40)           2      (40)           1     ( 20)
Rocky Mountain spotted fever           590         10     ( 2)         339      (57)         241     ( 41)
Rubella (German measles)               128         60     (47)          48      (38)          20     ( 16)
Rubella, congenital syndrome             6          5     (83)           1      (17)           -     ( - )
Salmonellosis                       45,970      2,937     ( 6)      18,124      (39)      24,909     ( 54)
Shigellosis                         32,080      3,673     (11)      12,575      (39)      15,832 +   ( 49)
Syphilis, primary and secondary &   16,501        686     ( 4)      15,461      (94)         354     (  2)
Tetanus                                 41          6     (15)          23      (56)          12     ( 29)
Toxic-shock syndrome                   191          7     ( 4)         121      (63)          63     ( 33)
Trichinosis                             29          3     (10)           6      (21)          20     ( 69)
Tuberculosis **                     22,860      4,847     (21)      17,872      (78)         141     (  1)
Typhoid fever                          369         86     (23)         178      (48)         105     ( 28)
----------------------------------------------------------------------------------------------------------
 * The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases reported to the Division of HIV/AIDS
   Prevention, National Center for HIV, STD, and TB Prevention (NCHSTP) through December 31, 1995.
 + Ethnicity is not stated and includes cases originally reported as American Indian or Alaskan Native and Asian or Pacific Islander.
 & Ethnicity data are collected on aggregate forms different from those used for numbers of reported cases. Thus, the total number
   of cases reported on this table may differ slightly from other tables. Cases were updated through the Division of Sexually Trans-
   mitted Diseases Prevention, NCHSTP, as of March 1, 1996. Ethnicity data for 1995 are unavailable for chancroid and chlamydia.
 @ Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation of these cases is pending review
   by an external panel.
** Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
=======================================================================================================================================

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Table_1
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TABLE 1. NOTIFIABLE DISEASES -- summary of reported cases, per 100,000 population, United States, 1986-1995
============================================================================================================================================
Disease                                         1986     1987     1988      1989     1990     1991     1992     1993     1994      1995
-----------------------------------------------------------------------------------------------------------------------------------------
AIDS *                                          5.36     8.66    12.61     13.58    16.72    17.32    17.83    40.20    30.07     27.20
Amebiasis                                       1.47     1.33     1.20      1.34     1.38     1.23     1.21     1.21     1.20       +
Anthrax                                         0.00     0.00     0.00      0.00     0.00     0.00     0.00     0.00     0.00      0.00
Aseptic meningitis                              4.72     4.72     2.94      4.14     4.77     6.26     5.18     5.39     3.71       +
Botulism, total (including wound and unsp.)     0.05     0.03     0.03      0.04     0.04     0.05     0.04     0.04     0.06      0.04
  Foodborne                                     0.01     0.01     0.01      0.01     0.01     0.01     0.00     0.01     0.02      0.01

Brucellosis                                     0.04     0.05     0.04      0.04     0.03     0.04     0.04     0.05     0.05      0.04
Chancroid                                       1.57     2.07     2.04      1.90     1.70     1.40     0.80     0.54     0.30      0.20 &
Chlamydia @                                    ..................................... ** .....................................    182.20 &
Cholera                                         0.01     0.00     0.00      0.00     0.00     0.01     0.04     0.00     0.02      0.01
Diphtheria                                      0.00     0.00     0.00      0.00     0.00     0.00     0.00     0.00     0.00      0.00
Encephalitis, primary                           0.54     0.58     0.36      0.40     0.54     0.40     0.30     0.36     0.28       +
  Post-infectious                               0.05     0.05     0.05      0.04     0.04     0.03     0.05     0.07     0.06       +

Escherichia coli O157:H7                       ................................. ** ................................     0.82      1.01
Gonorrhea                                     376.37   323.14   298.74    297.36   276.60   249.48   201.60   172.40   168.40    149.50 &
Granuloma inguinale                             0.03     0.01     0.00      0.00     0.00     0.01     0.00     0.00     0.00       +
Haemophilus influenzae, invasive               ................... ** ...................     1.10     0.55     0.55     0.45      0.45
Hansen disease (leprosy)                        0.11     0.10     0.07      0.07     0.08     0.06     0.07     0.07     0.05      0.06
Hepatitis A                                    10.02    10.39    11.60     14.43    12.64     9.67     9.06     9.40    10.29     12.13

Hepatitis B                                    11.17    10.65     9.43      9.43     8.48     7.14     6.32     5.18     4.81      4.19
Hepatitis, C/non-A, non-B ++                    1.55     1.23     1.07      1.02     1.03     1.42     2.36     1.86     1.78      1.78
Hepatitis, unspecified                          1.69     1.27     1.00      0.93     0.67     0.50     0.35     0.24     0.17       +
Legionellosis                                   0.43     0.43     0.44      0.48     0.55     0.53     0.53     0.50     0.63      0.48
Leptospirosis                                   0.02     0.02     0.02      0.04     0.03     0.02     0.02     0.02     0.02       +
Lyme disease                                   ................... ** ...................     3.80     0.12     3.20     5.01      4.49

Lymphogranuloma venereum                        0.16     0.13     0.07      0.08     0.10     0.19     0.10     0.10     0.10       +
Malaria                                         0.47     0.39     0.45      0.51     0.52     0.51     0.43     0.55     0.47      0.55
Measles (rubeola)                               2.61     1.50     1.38      7.33    11.17     3.82     0.88     0.12     0.37      0.12
Meningococcal disease                           1.08     1.20     1.21      1.10     0.99     0.84     0.84     1.02     1.11      1.25
Mumps                                           3.37     5.43     2.05      2.34     2.17     1.72     1.03     0.66     0.60      0.35
Murine typhus fever                             0.03     0.02     0.02      0.02     0.02     0.02     0.01     0.01    ...... + ......

Pertussis (whooping cough)                      1.74     1.16     1.40      1.67     1.84     1.08     1.60     2.55     1.77      1.97
Plague                                          0.00     0.00     0.01      0.00     0.00     0.00     0.01     0.00     0.01      0.00
Poliomyelitis, paralytic                        0.00     0.00     0.00      0.00     0.00     0.00     0.00     0.00     0.00      0.00
Psittacosis                                     0.09     0.04     0.05      0.05     0.05     0.04     0.04     0.02     0.02      0.03
Rabies, human                                   0.00     0.00     0.00      0.00     0.00     0.00     0.00     0.00     0.00      0.00
Rheumatic fever, acute                          0.12     0.13     0.14      0.13     0.09     0.12     0.06     0.08     0.09       +

Rocky Mountain spotted fever                    0.32     0.25     0.25      0.25     0.26     0.25     0.20     0.18     0.18      0.23
Rubella (German measles)                        0.23     0.13     0.09      0.16     0.45     0.56     0.06     0.07     0.09      0.05
Salmonellosis, excluding typhoid fever         20.73    20.92    19.91     19.26    19.54    19.10    16.04    16.15    16.64     17.66
Shigellosis                                     7.11     9.80    12.46     10.07    10.89     9.34     9.38    12.48    11.44     12.32
Syphilis, primary and secondary                11.65    14.54    16.43     18.07    20.10    17.26    13.70    10.40     8.10      6.30 &
  Total, all stages                            28.50    35.81    42.37     44.94    53.80    51.69    45.30    39.70    32.00     26.20 &

Tetanus                                         0.03     0.02     0.02      0.02     0.03     0.02     0.02     0.02     0.02      0.02
Toxic-shock syndrome                            0.19     0.15     0.16      0.16     0.13     0.11     0.10     0.08     0.10      0.07
Trichinosis                                     0.02     0.02     0.02      0.01     0.05     0.02     0.02     0.01     0.01      0.01
Tuberculosis                                    9.44     9.25     9.13      9.46    10.33    10.42    10.46     9.82     9.36      8.70
Tularemia                                       0.07     0.09     0.08      0.06     0.06     0.08     0.06     0.05     0.04       +
Typhoid fever                                   0.15     0.16     0.18      0.19     0.22     0.20     0.16     0.17     0.17      0.14
Varicella (chickenpox) &&                     122.42   136.68   122.43    121.77   120.06   135.82   176.54   118.54   135.76    118.11
Yellow fever                                  ............ Last indigenous case reported in 1911; last imported case, 1924 ............
-----------------------------------------------------------------------------------------------------------------------------------------
NOTE: Rates <0.01 after rounding are listed as 0.00.                                  ** Not previously nationally notifiable.
* Acquired immunodeficiency syndrome (AIDS).                                          ++ Anti-HCV antibody test became available May 1990.
+ No longer nationally notifiable.                                                    && Not nationally notifiable.
& DemoDetail 1991-1995 post-censal estimates were used to calculate 1995 rates.
@ Chlamydia refers to genital infections caused by C. trachomatis.
============================================================================================================================================

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Table_2
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TABLE 2. NOTIFIABLE DISEASES -- summary of reported cases, United States, 1988-1995
===================================================================================================================================================================================
Disease                                          1988      1989       1990       1991      1992       1993      1994       1995
-------------------------------------------------------------------------------------------------------------------------------
AIDS                                           31,001    33,722     41,595     43,672    45,472    103,533    78,279     71,547 *
Amebiasis                                       2,860     3,217      3,328      2,989     2,942      2,970     2,983          +
Anthrax                                             2         -          -          -         1          -         -          -
Aseptic meningitis                              7,234    10,274     11,852     14,526    12,223     12,848     8,932          +
Botulism, total (including wound and unsp.)        84        89         92        114        91         97       143         97
  Foodborne                                        28        23         23         27        21         27        50         24
  Infant                                           50        60         65         81        66         65        85         54

Brucellosis                                        96        95         85        104       105        120       119         98
Chancroid                                       5,001     4,692      4,212      3,476     1,886      1,399       773        606 &
Chalmydia @                                   .................................. ** ................................    477,638 &
Cholera                                             8         -          6         26       103         18        39         23
Diphtheria                                          2         3          4          5         4          -         2          -
Encephalitis, primary                             882       981      1,341      1,021       774        919       717          +
  Post-infectious                                 121        88        105         82       129        170       143          +

Escherichia coli O157:H7                      ............................ ** ............................     1,420      2,139
Gonorrhea                                     719,536   733,151    690,169    620,478   501,409    439,673   418,068    392,848 &
Granuloma inguinale                                11         7         97         29         6         19         3          +
Haemophilus influenzae, invasive              ............ ** ............    2,764     1,412      1,419     1,174      1,180
Hansen disease (leprosy)                          184       163        198        154       172        187       136        144
Hepatitis A                                    28,507    35,821     31,441     24,378    23,112     24,238    29,796     31,582

Hepatitis B                                    23,177    23,419     21,102     18,003    16,126     13,361    12,517     10,805
Hepatitis, C/non-A, non-B ++                    2,619     2,529      2,553      3,582     6,010      4,786     4,470      4,576
Hepatitis, unspecified                          2,470     2,306      1,671      1,260       884        627       444          +
Legionellosis                                   1,085     1,190      1,370      1,317     1,339      1,280     1,615      1,241
Leptospirosis                                      54        93         77         58        54         51        38          +
Lyme disease                                  ............ ** ............    9,465     9,895      8,257    13,043     11,700

Lymphogranuloma venereum                          185       189        277        471       302        285       235          +
Malaria                                         1,099     1,277      1,292      1,278     1,087      1,411     1,229      1,419
Measles (rubeola)                               3,396    18,193     27,786      9,643     2,237        312       963        281
Meningococcal disease                           2,964     2,727      2,451      2,130     2,134      2,637     2,886      3,243
Mumps                                           4,866     5,712      5,292      4,264     2,572      1,692     1,537        906
Murine typhus fever                                54        41         50         43        28         25  ......... + .......

Pertussis (whooping cough)                      3,450     4,157      4,570      2,719     4,083      6,586     4,617      5,137
Plague                                             15         4          2         11        13         10        17          9
Poliomyelitis, paralytic &&                         9         9          6         10         6          4         5          2
Psittacosis                                       114       116        113         94        92         60        38         64
Rabies, animal                                  4,651     4,724      4,826      6,910     8,589      9,377     8,147      7,811
Rabies, human                                       -         1          1          3         1          3         6          5

Rheumatic fever, acute                            158       144        108        127        75        112       112          +
Rocky Mountain spotted fever                      609       623        651        628       502        456       465        590
Rubella (German measles)                          225       396      1,125      1,401       160        192       227        128
Rubella, congenital syndrome                        6         3         11         47        11          5         7          6
Salmonellosis, excluding typhoid fever         48,948    47,812     48,603     48,154    40,912     41,641    43,323     45,970
Shigellosis                                    30,617    25,010     27,077     23,548    23,931     32,198    29,769     32,080

Syphilis, primary and secondary                40,117    44,540     50,223     42,935    33,973     26,498    20,627     16,500 &
  Total, all stages                           103,437   110,797    134,255    128,569   112,581    101,259    81,696     68,953 &
Tetanus                                            53        53         64         57        45         48        51         41
Toxic-shock syndrome                              390       400        322        280       244        212       192        191
Trichinosis                                        45        30        129         62        41         16        32         29
Tuberculosis                                   22,436    23,495     25,701     26,283    26,673     25,313    24,361     22,860 @@
Tularemia                                         201       152        152        193       159        132        96          +
Typhoid fever                                     436       460        552        501       414        440       441        369
Varicella (chickenpox) ***                    192,857   185,441    173,099    147,076   158,364    134,722   151,219    120,624
Yellow fever                                  ........ Last indigenous case reported in 1911; last imported case, 1924 ........
-------------------------------------------------------------------------------------------------------------------------------
  * The total number of acquired immunodeficiency syndrome (AIDS) cases includes all cases reported to the Division of HIV/AIDS Prevention, National Center for HIV, STD, and TB
    Prevention (NCHSTP) through December 31, 1995.
  + No longer nationally notifiable.
  & Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP, as of March 1, 1996.
  @ Chlamydia refers to genital infections caused by C. trachomatis.
 ** Not previously nationally notifiable.
 ++ Anti-HCV antibody test available May 1990.
 && Numbers may not reflect changes based on retrospective case evaluations or late reports (see MMWR 1986;35:180-2). Seven additional suspected cases of paralytic poliomyelitis
    were reported in 1995. Confirmation of these cases is pending review by an external panel.
 @@ Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.
*** Varicella was taken off the nationally notifiable disease list in 1991. Many states continue to report these cases to CDC.
===================================================================================================================================================================================

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Table_3
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TABLE 3. NOTIFIABLE DISEASES -- summary of reported cases, United States, 1980-1987
============================================================================================================================================================================================
Disease                                            1980      1981       1982      1983      1984        1985       1986      1987
---------------------------------------------------------------------------------------------------------------------------------
AIDS *                                            ............... + ..................     4,445       8,249     12,932    21,070
Amebiasis                                         5,271     6,632      7,304     6,658     5,252       4,433      3,532     3,123
Anthrax                                               1         -          -         -         1           -          -         1
Aseptic meningitis                                8,028     9,547      9,680    12,696     8,326      10,619     11,374    11,487
Botulism, total (including wound and unsp.)          89       103         97       133       123         122        109        82
  Foodborne                                       ..................... & ......................          49         23        17
  Infant                                          ..................... & ......................          70         79        59

Brucellosis                                         183       185        173       200       131         153        106       129
Chancroid                                           788       850      1,392       847       665       2,067      3,756     4,998
Cholera                                               9        19          -         1         1           4         23         6
Diphtheria                                            3         5          2         5         1           3          -         3
Encephalitis, primary @                           1,362     1,492      1,464     1,761     1,257       1,376      1,302     1,418
  Post-infectious @                                  40        43         36        34       108         161        124       121

Gonorrhea                                     1,004,029   990,864    960,633   900,435   878,556     911,419    900,868   780,905
Granuloma inguinale                                  51        66         17        24        30          44         61        22
Hansen disease (leprosy)                            223       256        250       259       290         361        270       238
Hepatitis A (infectious)                         29,087    25,802     23,403    21,532    22,040      23,210     23,430    25,280
Hepatitis B (serum)                              19,015    21,152     22,177    24,318    26,115      26,611     26,107    25,916
Hepatitis, non-A, non-B                           .......... + .............     3,470     3,871       4,184      3,634     2,999

Hepatitis, unspecified                           11,894    10,975      8,564     7,149     5,531       5,517      3,940     3,102
Legionellosis **                                    475       408        654       852       750         830        980     1,038
Leptospirosis                                        85        82        100        61        40          57         41        43
Lymphogranuloma venereum                            199       263        235       335       170         226        396       303
Malaria                                           2,062     1,388      1,056       813     1,007       1,049      1,123       944
Measles (rubeola)                                13,506     3,124      1,714     1,497     2,587       2,822      6,282     3,655

Meningococcal disease                             2,840     3,525      3,056     2,736     2,746       2,479      2,594     2,930
Mumps                                             8,576     4,941      5,270     3,355     3,021       2,982      7,790    12,848
Murine typhus fever                                  81        61         58        62        53          37         67        49
Pertussis (whooping cough)                        1,730     1,248      1,895     2,463     2,276       3,589      4,195     2,823

Plague                                               18        13         19        40        31          17         10        12
Poliomyelitis, total                                  9         6          8        15         8       ........... ++ ...........
  Paralytic                                           9        10         11        13         9           7          9         9
Psittacosis                                         124       136        152       142       172         119        224        98
Rabies, animal                                    6,421     7,118      6,212     5,878     5,567       5,565      5,504     4,658
Rabies, human                                         -         2          -         2         3           1          -         1
Rheumatic fever, acute                              432       264        137        88       117          90        147       141
Rocky Mountain spotted fever                      1,163     1,192        976     1,126       838         714        760       604
Rubella (German measles)                          3,904     2,077      2,325       970       752         630        551       306

Rubella, congenital syndrome                         50        19          7        22         5           -         14         5
Salmonellosis, excluding typhoid fever           33,715    39,990     40,936    44,250    40,861      65,347     49,984    50,916
Shigellosis                                      19,041    19,859     18,129    19,719    17,371      17,057     17,138    23,860
Syphilis, primary and secondary                  27,204    31,266     33,613    32,698    28,607      27,131     27,883    35,147
  Total, all stages                              68,832    72,799     75,579    74,637    69,888      67,563     68,215    86,545
Tetanus                                              95        72         88        91        74          83         64        48

Toxic-shock syndrome                              .......... + .............       502       482         384        412       372
Trichinosis                                         131       206        115        45        68          61         39        40
Tuberculosis                                     27,749    27,373     25,520    23,846    22,255      22,201     22,768    22,517
Tularemia                                           234       288        275       310       291         177        170       214
Typhoid fever                                       510       584        425       507       390         402        362       400
Varicella (chickenpox)                          190,894   200,766    167,423   177,462   221,983     178,162    183,243   213,196
Yellow fever                                     ....... Last indigenous case reported in 1911; last imported case, 1924 ........
---------------------------------------------------------------------------------------------------------------------------------
 * Acquired immunodeficiency syndrome (AIDS).
 + Not previously notifiable nationally.
 & Not reported as distinct categories during this period.
 @ Beginning in 1984, data reflects change in categories for tabulating encephalitis reports that were recorded by date of report to state health departments. Data for previous years are
   from surveillance records reported by onset date.
** Beginning in 1982, data were recorded by date of report to the state health department. Data for 1976-1981 are from surveillance records reported by onset date.
++ Categories other than paralytic are no longer reported.
============================================================================================================================================================================================

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Table_4
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TABLE 4. NOTIFIABLE DISEASES -- summary of reported cases, United States, 1972-1979
==============================================================================================================================================
Disease                                          1972      1973       1974      1975        1976         1977        1978        1979
-------------------------------------------------------------------------------------------------------------------------------------
Amebiasis                                       2,199     2,235      2,743     2,775       2,906        3,044       3,937       4,107
Anthrax                                             2         2          2         2           2            -           6           -
Aseptic meningitis                              4,634     4,846      3,197     4,475       3,510        4,789       6,573       8,754
Botulism, total (including wound and unsp.)        22        34         28        20          55          129         105          45
Brucellosis                                       196       202        240       310         296          232         179         215
Chancroid                                       1,414     1,165        945       700         628          455         521         840

Cholera                                             -         1          -         -           -            3          12           1
Diphtheria                                        152       228        272       307         128           84          76          59
Encephalitis, primary                           1,059     1,613      1,164     4,064       1,651        1,414       1,351       1,504
  Post-infectious                                 243       354        218       237         175          119          78          84
Gonorrhea                                     767,215   842,621    906,121   999,937   1,001,994    1,002,219   1,013,436   1,004,058
Granuloma inguinale                                81        62         47        60          71           75          72          76

Hansen disease (leprosy)                          130       146        118       162         145          151         168         185
Hepatitis A (infectious)                       54,074    50,749     40,358    35,855      33,288       31,153      29,500      30,407
Hepatitis B (serum)                             9,402     8,451     10,631    13,121      14,973       16,831      15,016      15,452
Hepatitis, unspecified                          ...... * ......      8,351     7,158       7,488        8,639       8,776      10,534
Legionellosis                                   ................ * .................         235          359         761         593
Leptospirosis                                      41        57         68        93          73           71         110          94

Lymphogranuloma venereum                          756       408        394       353         365          348         284         250
Malaria                                           742       237        293       373         471          547         731         894
Measles (rubeola)                              32,275    26,690     22,094    24,374      41,126       57,345      26,871      13,597
Meningococcal disease                           1,323     1,378      1,346     1,478       1,605        1,828       2,505       2,724
Mumps                                          74,215    69,612     59,128    59,647      38,492       21,436      16,817      14,225
Murine typhus fever                                18        32         26        41          69           75          46          69

Pertussis (whooping cough)                      3,287     1,759      2,402     1,738       1,010        2,177       2,063       1,623
Plague                                              1         2          8        20          16           18          12          13
Poliomyelitis, total                               31         8          7         8          14           18          15          34
  Paralytic                                        29         7          7         8          12           17           9          26
Psittacosis                                        52        33        164        49          78           94         140         137
Rabies, animal                                  4,369     3,640      3,151     2,627       3,073        3,130       3,254       5,119

Rabies, human                                       2         1          -         2           2            2           4           4
Rheumatic fever, acute                          2,614     2,560      2,431     2,854       1,865        1,738         851         629
Rocky Mountain spotted fever                      523       668        754       844         937        1,153       1,063       1,070
Rubella (German measles)                       25,507    27,804     11,917    16,652      12,491       20,395      18,269      11,795
Rubella, congenital syndrome                       42        35         45        30          30           23          30          62
Salmonellosis, excluding typhoid fever         22,151    23,818     21,980    22,612      22,937       27,850      29,410      33,138

Shigellosis                                    20,207    22,642     22,600    16,584      13,140       16,052      19,511      20,135
Syphilis, primary and secondary                24,429    24,825     25,385    25,561      23,731       20,399      21,656      24,874
  Total, all stages                            91,149    87,469     83,771    80,356      71,761       64,621      64,875      67,049
Tetanus                                           128       101        101       102          75           87          86          81
Trichinosis                                        89       102        120       252         115          143          67         157
Tuberculosis +                                 32,882    30,998     30,122    33,989      32,105       30,145      28,521      27,669

Tularemia                                         152       171        144       129         157          165         141         196
Typhoid fever                                     398       680        437       375         419          398         505         528
Varicella (chickenpox)                        164,114   182,927    141,495   154,248     183,990      188,396     154,089     199,081
Yellow fever                                  ........... Last indigenous case reported in 1911, last imported case 1924 ............
-------------------------------------------------------------------------------------------------------------------------------------
* Not previously notifiable nationally.
+ Case data subsequent to 1974 are not comparable with earlier years because of changes in reporting criteria that became effective in 1975.
==============================================================================================================================================

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Table_5
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TABLE 5. NOTIFIABLE DISEASES -- summary of reported cases, United States, 1966-1971
===========================================================================================================
Disease                                          1966      1967       1968      1969       1970      1971
---------------------------------------------------------------------------------------------------------
Amebiasis                                       2,921     3,157      3,005     2,915      2,888     2,752
Anthrax                                             5         2          3         4          2         5
Aseptic meningitis                              3,058     3,082      4,494     3,672      6,480     5,176
Botulism                                            9         5          7        16         12        25
Brucellosis                                       262       265        218       235        213       183
Chancroid                                         838       784        845     1,104      1,416     1,320

Cholera                                             -         -          -         -          -         1
Diphtheria                                        209       219        260       241        435       215
Encephalitis, primary                           2,121     1,478      1,781     1,613      1,580     1,524
  Post-infectious                                 964     1,060        502       304        370       439
Gonorrhea                                     351,738   404,836    464,543   534,872    600,072   670,268
Granuloma inguinale                               148       154        156       154        124        89

Hansen disease (leprosy)                          109        81        123        98        129       131
Hepatitis A (infectious)                       32,859    38,909     45,893    48,416     56,797    59,606
Hepatitis B (serum)                             1,497     2,458      4,829     5,909      8,310     9,556
Leptospirosis                                      72        67         69        89         47        62
Lymphogranuloma venereum                          308       371        485       520        612       692
Malaria                                           565     2,022      2,317     3,102      3,051     2,375

Measles (rubeola)                             204,136    62,705     22,231    25,826     47,351    75,290
Meningococcal disease                           3,381     2,161      2,623     2,951      2,505     2,262
Mumps                                           ...... * ......    152,209    90,918    104,953   124,939
Murine typhus fever                                33        52         36        36         27        23
Pertussis (whooping cough)                      7,717     9,718      4,810     3,285      4,249     3,036
Plague                                              5         3          3         5         13         2

Poliomyelitis, total                              113        41         53        20         33        21
  Paralytic                                       106        40         53        18         31        17
Psittacosis                                        50        41         43        57         35        32
Rabies, animal                                  4,178     4,481      3,591     3,490      3,224     4,310
Rabies, human                                       1         2          1         1          3         2
Rheumatic fever, acute                          4,472     3,985      3,470     3,229      3,227     2,793

Rocky Mountain spotted fever                      268       305        298       498        380       432
Rubella (German measles)                       46,975    46,888     49,371    57,686     56,552    45,086
Rubella, congenital syndrome                       11        10         14        31         77        68
Salmonellosis, excluding typhoid fever         16,841    18,120     16,514    18,419     22,096    21,928
Shigellosis                                    11,888    13,474     12,180    11,946     13,845    16,143
Streptococcal sore throat and scarlet fever   427,752   453,351    435,013   450,008    433,405         +
Syphilis, primary and secondary                21,414    21,053     19,019    19,130     21,982    23,783
  Total, all stages                           105,159   102,581     96,271    92,162     91,382    95,997
Tetanus                                           235       263        178       192        148       116
Trichinosis                                       115        66         77       215        109       103
Tuberculosis                                   47,767    45,647     42,623    39,120     37,137    35,217
Tularemia                                         208       184        186       149        172       187
Typhoid fever                                     378       396        395       364        346       407
Yellow fever                      ... Last indigenous case reported in 1911; last imported case, 1924 ...
---------------------------------------------------------------------------------------------------------
* Not previously notifiable nationally.
+ No longer nationally notifiable.
===========================================================================================================

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Table_6
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TABLE 6. NOTIFIABLE DISEASES -- deaths from selected diseases, United States, 1984-1993. (Numbers in ICD column refer
to the category numbers listed in the Ninth Revision of the International Classification of  Diseases, 1994.)
===========================================================================================================================================================================================
Cause of Death                                       ICD *     1984     1985       1986      1987       1988      1989      1990       1991      1992     1993
--------------------------------------------------------------------------------------------------------------------------------------------------------------
AIDS +                                           *042-*044    2,943    6,040     10,900    13,468     16,602    22,082    25,188     29,555    33,566   37,267
Anthrax                                                022        -        -          -         -          -         -         -          -         -        -
Botulism, foodborne                                  005.1        4        4          1         -          1         2         4          2         1        -
Brucellosis                                            023        -        1          1         1          2         -         -          -         -        1
Chancroid                                            099.0        -        -          -         -          -         -         -          1         -        -
Cholera                                                001        -        1          -         1          -         -         2          2         2        -
Diphtheria                                             032        -        -          -         1          -         -         1          -         1        -
Gonococcal infections                                  098        3        2          7         7          3         4         3          3         4        5
Haemophilus influenzae, invasive                     041.5       14       22         21        25         25        16        16         17        16        7
Hansen disease (leprosy)                               030        6        2          1         1          -         4         3          -         2        1
Hepatitis, viral, infectious (Hep A)           070.0,070.1       77       80         65        77         70        88        76         71        82       95
Hepatitis, viral, serum (Hep B)                070.2,070.3      465      490        557       595        621       711       816        912       903     1041
Hepatitis, viral, other and unsp.              070.4-070.9      327      372        384       510        599       717       686        857     1,016     1353
Lyme disease                                        088.81        -        -          -         -          -         -         -          -         -        -
Malaria                                                084        7       13          5         5          7        11         3          4         8       12
Measles (rubeola)                                      055        3        4          2         2          3        32        64         27         4        -
Meningococcal disease                                  036      300      257        286       258        278       273       215        198       201      260
Mumps                                                  072        1        -          -         2          2         3         1          1         -        -
Pertussis (whooping cough)                             033        7        4          6         1          4        12        12          -         5        7
Plague                                                 020        3        1          -         1          -         -         -          -         1        2
Poliomyelitis, total                           045.0-045.9        -        3          -         -          1         -         -          1         -        -
Psittacosis                                            073        -        1          -         2          1         1         2          -         4        1
Rabies, human                                          071        2        -          -         1          -         1         1          3         1        1
Rocky Mountain spotted fever                         082.0       34       22         19        21         20        10        20         13        13        5
Rubella (German measles)                               056        1        1          1         -          1         4         8          1         1        -
Salmonellosis, incl. paratyphoid fever     002.1-002.9,003       90      117        102       105         66        99        80         53        47       52
Shigellosis                                            004        8       17          4        13          8        16        10         10         8        5
Syphilis                                           090-097      105       80         80        98         85       105       106         93        91       80
Tetanus                                                037       20       23         22        16         17         9        11         11         9       11
Trichinosis                                            124        -        1          -         -          -         1         -          -         -        -
Tuberculosis (all forms)                           010-018    1,729    1,752      1,782     1,755      1,921     1,970     1,810      1,713     1,705     1631
Typhoid fever                                        002.0        -        -          2         2          -         -         1          1         -        -
Varicella (chickenpox)                                 052       53       68         47        89         83        89       120         81       100      100
--------------------------------------------------------------------------------------------------------------------------------------------------------------
* Numbers in ICD column refer to the category numbers listed in the Ninth Revision of the International Classification of Diseases, 1994. (The asterisks in the ICD column pertain to the
  ICD code, not a footnote. They indicate that the numbers are not part of the ICD but were introduced for use in the United States.)
+ For 1983-1986, deaths are estimated from death certificates that mention conditions coded to deficiency of cell-mediated immunity (ICD-9 No.279.1). These numbers include other
  human immunodeficiency virus (HIV)-related deaths and other diseases classifiable as deficiencies of cell-mediated immunity.

Source: National Center for Health Statistics System, 1984-1993. Deaths are classified to the Ninth Revision, ICD.
===========================================================================================================================================================================================

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Table_B2
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NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995 (continued)
========================================================================================================================
                                             Escherichia coli O157:H7                 Haemophilus
                                             ------------------------                 influenzae,
Area                 Chlamydia *+    Cholera    NETSS &    PHLIS @    Gonorrhea +       invasive
-------------------------------------------------------------------------------------------------
United States          477,638          23       2,139      1,531       392,848          1,180

New England             18,248           -         243        139         7,539             46
  Maine                  1,144           -          65          -            94              3
  N.H.                     898           -          NA         21           118             13
  Vt.                      462           -          20         22            69              2
  Mass.                  7,402           -         118         96         2,658             16
  R.I.                   1,902           -           3          -           545              5
  Conn.                  6,440           -          37          -         4,055              7

Mid. Atlantic           53,703           4         242        209        44,813            177
  N.Y. (excl. NYC)          NN           1         169        114         9,493             45
  N.Y.C.                26,686           1           7          -        16,499             36
  N.J.                   4,056           1          66         51         5,783             32
  Pa.                   22,961           1          NN         44        13,038             64

E.N. Central            93,492           2         372        358        77,547            190
  Ohio                  29,124           -         107         59        23,176             99
  Ind.                   9,102           1          64         42         8,880             22
  Ill.                  24,645           1         126         90        21,747             48
  Mich.                 21,666           -          75         49        18,220             18
  Wis.                   8,955           -          NN        118         5,524              3

W.N. Central            34,055           1         415        278        20,106             94
  Minn.                  6,032           1         199        186         2,852             56
  Iowa                   5,089           -          66         52         1,723              3
  Mo.                   12,110           -          48          -        11,326             28
  N. Dak.                1,324           -           8          8            38              -
  S. Dak.                1,313           -          23         12           237              1
  Nebr.                  2,873           -          42          -         1,133              3
  Kans.                  5,314           -          29         20         2,797              3

S. Atlantic             85,575           2         135         83       110,052            236
  Del.                   2,701           1           5          2         2,201              -
  Md.                    8,740           -          NN          8        12,984             74
  D.C.                   1,665           -           -          -         5,687              -
  Va.                   12,285           -          NN         32        10,340             28
  W. Va.                 2,326           -          NN          3           860             11
  N.C.                  15,780           -          45         29        23,961             34
  S.C.                   8,591           -          10          5        12,120              3
  Ga.                   11,193           -          29          -        21,025             71
  Fla.                  22,294           1          46          4        20,874             15

E.S. Central            24,158           -          38         38        42,837             12
  Ky.                    6,904           -          19         15         4,751              5
  Tenn.                 13,154           -          NN         23        13,892              -
  Ala.                   3,188           -          16          -        14,683              6
  Miss.                    912           -           3          -         9,511              1

W.S. Central            59,483           2          69         18        50,800             80
  Ark.                     680           -          15          7         5,630              6
  La.                    9,111           -          NN          3         9,292              1
  Okla.                  5,065           -          16          8         5,077             31
  Tex.                  44,627           2          38          -        30,801             42

Mountain                29,361           3         278        122         9,509            122
  Mont.                  1,198           -          60          -            65              1
  Idaho                  1,739           -          63         35           149              6
  Wyo.                     703           -          NN          7            51             11
  Colo.                  6,650           1          93         37         2,803             16
  N. Mex.                4,285           1          10          5         1,054             16
  Ariz.                 10,061           1          NN         26         3,844             30
  Utah                   1,676           -          29          -           306             12
  Nev.                   3,049           -          23         12         1,237             30

Pacific                 79,563           9         347        286        29,645            223
  Wash.                  9,462           -         140        132         2,765             11
  Oreg.                  5,465           -          89         61           854             28
  Calif.                62,501           9         118         77        24,803            178
  Alaska                    NN           -          NN          1           660              2
  Hawaii                 2,135           -          NN         15           563              4

  Guam                     461           -           1          -            90              -
  P.R.                   2,305           -          43         NA           618              3
  V.I.                      17           -           -         NA            31              -
  C.N.M.I.                  NA           9          NN          -            NA             11
  American Samoa            NA          NA          NA         NA            NA             NA
-------------------------------------------------------------------------------------------------
* Chlamydia refers to genital infections caused by C. trachomatis.                               NA: Not Available
+ Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP,   NN: Not Notifiable
  as of March 1, 1996.                                                                            -: No reported cases
& Data from the National Electronic Telecommunications System for Surveillance.
@ Data from the Public Health Laboratory Information System.
========================================================================================================================

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Table_B3
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NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995 (continued)
============================================================================================
                                        Hepatitis
                     Hansen     --------------------------
                     disease                      C/non-A,   Legionel-    Lyme
Area                (leprosy)      A        B      non-B       losis     disease   Malaria
------------------------------------------------------------------------------------------
United States             144   31,582   10,805    4,576       1,241     11,700     1,419

New England                 7      333      252      142          41      2,164        52
  Maine                     -       30       12        -           6         45         7
  N.H.                      -       13       23       14           2         28         2
  Vt.                       -        8        7       14           2          9         1
  Mass.                     7      161      114      106          24        189        21
  R.I.                      -       35       10        8           7        345         4
  Conn.                     -       86       86        -          NN      1,548        17

Mid. Atlantic              14    2,091    1,599      590         226      7,703       402
  N.Y. (excl. NYC)          1      523      414      341          65      3,983        75
  N.Y.C.                   12    1,008      524        1           6        455       222
  N.J.                      1      312      368      189          33      1,703        73
  Pa.                       -      248      293       59         122      1,562        32

E.N. Central                3    3,160    1,130      358         341        441       160
  Ohio                      1    1,760      116       15         151         30        13
  Ind.                      1      189      241       14          81         19        20
  Ill.                      1      663      293       86          36         18        78
  Mich.                     -      364      398      243          35          5        26
  Wis.                      -      184       82        -          38        369        23

W.N. Central                2    1,992      675       91         121        306        36
  Minn.                     -      198       93        4          49        208        12
  Iowa                      -      107       46       15          21         16         3
  Mo.                       1    1,338      437       23          19         53         9
  N. Dak.                   -       23        5        7           3          -         2
  S. Dak.                   -       99        2        1           3          -         2
  Nebr.                     1       65       39       23          18          6         4
  Kans.                     -      162       53       18           8         23         4

S. Atlantic                 4    1,434    1,599      316         199        726       277
  Del.                      -       12        9        -           2         56         1
  Md.                       2      221      262        7          29        454        63
  D.C.                      -       26       21        -           5          3        16
  Va.                       -      238      118       21          28         55        55
  W. Va.                    -       24       53       44           4         26         4
  N.C.                      -      111      311       64          34         84        20
  S.C.                      1       46       56       21          30         17         3
  Ga.                       -       84      103       28          19         14        41
  Fla.                      1      672      666      131          48         17        74

E.S. Central                -    2,312      830    1,020          56         73        27
  Ky.                       -       44       69       34          10         16         3
  Tenn.                     -    1,951      647      983          26         28        10
  Ala.                      -       93      114        3           8         12        11
  Miss.                     -      224       NA       NA          12         17         3

W.S. Central               38    5,287    1,712      631          32        160       100
  Ark.                      1      663       83        8           8         11         3
  La.                       1      196      243      222           3          9         7
  Okla.                     -    1,427      173       54           8         63         1
  Tex.                     36    3,001    1,213      347          13         77        89

Mountain                    -    4,346      879      519         116         13        66
  Mont.                     -      173       24       18           4          -         3
  Idaho                     -      353      102       58           3          -         2
  Wyo.                      -      110       33      223          12          4         1
  Colo.                     -      509      138       69          42          -        26
  N. Mex.                   -      808      321       53           6          1         7
  Ariz.                     -    1,363      121       59          13          1        15
  Utah                      -      696       75       13          16          1         6
  Nev.                      -      334       65       26          20          6         6

Pacific                    76   10,627    2,129      909         109        114       299
  Wash.                     3      937      226      234          22         10        23
  Oreg.                     1    2,723      129       37           -         20        21
  Calif.                   52    6,751    1,729      511          82         84       238
  Alaska                    1       50       13        3           -          -         5
  Hawaii                   19      166       32      124           5          -        12

  Guam                      7       10        5        6           1          -         2
  P.R.                      -      120      689      216           -          -         1
  V.I.                      -        9       16        -           -          -         2
  C.N.M.I.                  6       24       22        5           -          -         1
  American Samoa           NA       NA       NA       NA          NA         NA        NA
------------------------------------------------------------------------------------------
                                                                     NA: Not Available
                                                                     NN: Not Notifiable
                                                                      -: No reported cases
============================================================================================

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Table_B4
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NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995 (continued)
=============================================================================================================================
                             Measles           Meningo-                                     Polio-
                     ------------------------    coccal                                     myelitis,
Area                 Indigenous    Imported *   disease     Mumps    Pertussis   Plague    paralytic +
------------------------------------------------------------------------------------------------------
United States           281           28         3,243       906       5,137        9          2

New England              10            3           165        13         731        -          -
  Maine                   -            -            17         4          47        -          -
  N.H.                    -            -            29         1          70        -          -
  Vt.                     -            -            11         -          81        -          -
  Mass.                   3            2            51         3         492        -          -
  R.I.                    6            -             7         1           7        -          -
  Conn.                   1            1            50         4          34        -          -

Mid. Atlantic             9            5           372       134         469        -          1
  N.Y. (excl. NYC)        1            -           106        33         253        -          -
  N.Y.C.                  2            3            54        17          67        -          -
  N.J.                    6            2            74        21          20        -          -
  Pa.                     -            -           138        63         129        -          1

E.N. Central             11            4           419       172         667        -          -
  Ohio                    1            1           115        54         175        -          -
  Ind.                    -            -            65        10          76        -          -
  Ill.                    -            2           110        48         155        -          -
  Mich.                   4            1            75        60         103        -          -
  Wis.                    6            -            54         -         158        -          -

W.N. Central             12            -           201        52         369        -          1
  Minn.                   9            -            31        11         238        -          -
  Iowa                    -            -            31        11          11        -          -
  Mo.                     2            -            76        25          63        -          -
  N. Dak.                 -            -             2         1           8        -          1
  S. Dak.                 -            -            11         -          12        -          -
  Nebr.                   -            -            22         4          14        -          -
  Kans.                   1            -            28         -          23        -          -

S. Atlantic              14            5           601       163         388        -          -
  Del.                    -            -             6         -          10        -          -
  Md.                     -            1            42        41          49        -          -
  D.C.                    -            -             8         -           8        -          -
  Va.                     -            -            64        28          31        -          -
  W. Va.                  -            -            10         -           1        -          -
  N.C.                    -            -            86        42         137        -          -
  S.C.                    -            -            59        13          28        -          -
  Ga.                     4            -           124        11          30        -          -
  Fla.                   10            4           202        28          94        -          -

E.S. Central              -            -           244        20         277        -          -
  Ky.                     -            -            51         -          27        -          -
  Tenn.                   -            -           106         5         209        -          -
  Ala.                    -            -            49         5          38       NN          -
  Miss.                   -            -            38        10           3        -          -

W.S. Central             31            3           404        66         342        -          -
  Ark.                    2            -            39         7          59        -          -
  La.                    17            1            63        15          22        -          -
  Okla.                   -            -            49         1          44        -          -
  Tex.                   12            2           253        43         217        -          -

Mountain                 68            2           218        33         743        5          -
  Mont.                   -            -             4         1           9        -          -
  Idaho                   1            1            21         4         116        -          -
  Wyo.                    -            -             8         -           1        -          -
  Colo.                  26            -            49         3         149        -          -
  N. Mex.                30            1            36        NN         148        4          -
  Ariz.                  10            -            63         2         164        1          -
  Utah                    -            -            18        11          37        -          -
  Nev.                    1            -            19        12         119        -          -

Pacific                 126            6           619       253       1,151        4          -
  Wash.                  20            -           126        16         491        -          -
  Oreg.                   -            1           117        NN          67        1          -
  Calif.                106            3           356       211         531        3          -
  Alaska                  -            -            15        12           1        -          -
  Hawaii                  -            2             5        14          61        -          -

  Guam                    -            -             3         4           2        -          -
  P.R.                    3            -            24         3           3        -          -
  V.I.                    -            -             -         3           -        -          -
  C.N.M.I.                -            -             -         1           -        -          -
  American Samoa         NA           NA            NA        NA          NA       NA         NA
------------------------------------------------------------------------------------------------------
* Imported cases include only those imported from other countries.                                    NA: Not Available
+ Seven additional suspected cases of paralytic poliomyelitis were reported in 1995. Confirmation     NN: Not Notifiable
  of these cases is pending review by an external panel.                                               -: No reported cases
=============================================================================================================================

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Table_B5
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NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995 (continued)
==========================================================================================================
                                                                   Rubella
                                    Rabies                   -------------------
                     Psitta-    ---------------                          Cong.      Salmonel-    Shigel-
Area                  cosis     Animal    Human    RMSF *    Rubella    syndrome      losis       losis
--------------------------------------------------------------------------------------------------------
United States          64       7,811       5       590        128         6         45,970      32,080

New England             1       1,512       1         2         52         -          3,355         664
  Maine                 1         101       -         -          -         -            183          25
  N.H.                  -         152       -         -          1         -            188          71
  Vt.                   -         179       -         -          -         -            102          11
  Mass.                 -         401       -         1         11         -          1,862         324
  R.I.                  -         317       -         -          -         -            221          70
  Conn.                 -         362       1         1         40         -            799         163

Mid. Atlantic          12       1,923       -        43         16         1          8,157       3,531
  N.Y. (excl. NYC)      5       1,157       -        12          5         -          1,912         985
  N.Y.C.                -           -       -         6          8         1          2,159         845
  N.J.                  1         326       -        15          3         -          1,734       1,038
  Pa.                   6         440       -        10          -         -          2,352         663

E.N. Central            8         113       -        37          4         -          6,203       3,299
  Ohio                  1          12       -        17          -         -          1,545         598
  Ind.                  2          24       -         9          -         -            701         411
  Ill.                  -          16       -        10          -         -          2,087       1,539
  Mich.                 2          43       -         1          4         -            950         487
  Wis.                  3          18       -         -          -         -            920         264

W.N. Central            -         396       -        41          1         1          2,602       2,560
  Minn.                 -          37       -         -          -         -            737         197
  Iowa                  -         141       -         -          -         -            433         350
  Mo.                   -          30       -        30          -         1            577       1,138
  N. Dak.               -          32       -         -          -         -             83         146
  S. Dak.               -         105       -         1          -         -            108         200
  Nebr.                 -           5       -         6          -         -            301         227
  Kans.                 -          46       -         4          1         -            363         302

S. Atlantic            15       2,254       1       280         14         -          9,961       5,895
  Del.                  -          96       -         3          -         -            208         247
  Md.                   2         439       -        36          1         -          1,215         639
  D.C.                  -          11       -         -          -         -            154         197
  Va.                   1         459       -        34          -         -          1,358         412
  W. Va.                -         116       -         4          -         -            169          59
  N.C.                  3         466       -       150          1         -          1,176       1,006
  S.C.                  3         125       -        37          -         -            633         251
  Ga.                   5         294       -         9          -         -          1,662       1,358
  Fla.                  1         248       1         7         12         -          3,386       1,726

E.S. Central            1         285       -        83          1         -          2,022       1,575
  Ky.                   -          28       -        16          -         -            433         332
  Tenn.                 1          98       -        32          1         -            454         400
  Ala.                  -         150       -         3          -         -            581         510
  Miss.                 -           9       -        32         NN         -            554         333

W.S. Central            -         728       -        86          8         -          3,743       3,932
  Ark.                  -          52       -        31          -         -            338         176
  La.                   -          54       -         2          -         -            590         485
  Okla.                 -          32       -        47          -         -            452         254
  Tex.                  -         590       -         6          8         -          2,363       3,017

Mountain                4         192       -        16          5         -          2,198       4,538
  Mont.                 -          46       -         5          -         -            103         286
  Idaho                 -           3       -         -          -         -             85         124
  Wyo.                  -          32       -         5          -         -             37          15
  Colo.                 2          16       -         5          1         -            594         528
  N. Mex.               -           6       -         -          -         -            342       1,089
  Ariz.                 -          57       -         -          3         -            519       1,610
  Utah                  1          15       -         1          1         -            280         764
  Nev.                  1          17       -         -          -         -            238         122

Pacific                23         408       3         2         27         4          7,729       6,086
  Wash.                 7          15       1         1          1         -            691         425
  Oreg.                 3           4       -         1          -         -            344         168
  Calif.               13         382       2         -         21         4          6,343       5,371
  Alaska                -           7       -        NN          -         -             48          20
  Hawaii                -           -       -         -          5         -            303         102

  Guam                  -           -       -         -          1         -             40          19
  P.R.                  -          39       -         -          -         -            770          57
  V.I.                  -           -       -         -          -         -              9           6
  C.N.M.I.              -           -       -         -          -         -             42          41
  American Samoa       NA          NA      NA        NA         NA        NA             NA          NA
--------------------------------------------------------------------------------------------------------
* Rocky Mountain spotted fever.                                                    NA: Not Available
                                                                                   NN: Not Notifiable
                                                                                    -: No reported cases
==========================================================================================================

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Table_B6
Note: To print large tables and graphs users may have to change their printer settings to landscape and use a small font size.

NOTIFIABLE DISEASES -- Reported cases, by geographic division and area,
United States, 1995 (continued)
============================================================================================================================
                                Syphilis *
                      -------------------------------               Toxic-
                      Primary &     Cong.       All                 shock     Trich-     Tuber-     Typhoid
Area                  secondary    (<1 yr.)    stages    Tetanus   syndrome   inosis    culosis +    fever
-----------------------------------------------------------------------------------------------------------
United States          16,500       1,463      68,953      41        191        29       22,860       369

New England               161           9         905       -          7         2          574        35
  Maine                     2           -           4       -          1         -           28         -
  N.H.                      -           -          32       -          -         -           23         1
  Vt.                       -           -           -       -          2         -            4         -
  Mass.                    69           2         508       -          -         1          330        31
  R.I.                      4           -          90       -          4         -           50         1
  Conn.                    86           7         271       -          -         1          139         2

Mid. Atlantic             885         415      12,230       4         35         2        4,588       120
  N.Y. (excl. NYC)         85          45         999       2         20         -          621        12
  N.Y.C.                  364         191       7,791       -          4         1        2,445        66
  N.J.                    188         109       1,490       -          -         1          848        27
  Pa.                     248          70       1,950       2         11         -          674        15

E.N. Central            2,732         202       8,257       8         44         3        2,044        41
  Ohio                    896          44       1,944       2          8         -          280         5
  Ind.                    321          10         880       1          3         2          199         3
  Ill.                  1,026         121       3,649       4         11         -        1,024        25
  Mich.                   304          21       1,204       1         17         -          424         4
  Wis.                    185           6         580       -          5         1          117         4

W.N. Central              738          48       1,822       8         34         8          618         9
  Minn.                    45           -         187       3          6         -          156         5
  Iowa                     48           -         171       -          5         8           72         -
  Mo.                     584          46       1,271       3         14         -          244         3
  N. Dak.                   -           -           -       -          1         -            5         -
  S. Dak.                   -           -           7       -          1         -           28         -
  Nebr.                    14           -          35       -          5         -           24         -
  Kans.                    47           2         151       2          2         -           89         1

S. Atlantic             4,212         297      15,862       6         24         -        4,113        43
  Del.                     19           1         129       -          -         -           56         1
  Md.                     479          14       1,471       -          2         -          370         6
  D.C.                    112          18         727       -          -         -          102         -
  Va.                     600          22       1,587       -          3         -          359        10
  W. Va.                   16           -          66       1          -         -           71         3
  N.C.                  1,132          25       3,058       -          7         -          519         5
  S.C.                    570          49       1,676       -          4         -          334         -
  Ga.                     901          53       3,678       1          1         -          746         -
  Fla.                    383         115       3,470       4          7         -        1,556        18

E.S. Central            3,655         133       9,298       1          7         -        1,483         2
  Ky.                     185           8         502       -          2         -          327         -
  Tenn.                   906          33       2,608       1          5         -          465         1
  Ala.                    612          10       1,639       -          -         -          420         1
  Miss.                 1,952          82       4,549       -         NN         -          271         -

W.S. Central            3,273         228      13,423       5          1         -        3,353        24
  Ark.                    495           4       1,245       -          1         -          271         1
  La.                   1,024          17       3,675       2          -         -          476         1
  Okla.                   197          13         585       -          -         -          237         1
  Tex.                  1,557         194       7,918       3          -         -        2,369        21

Mountain                  204          12       1,129       3         10        11          702         5
  Mont.                     4           -          13       -          -         -           21         -
  Idaho                     -           -          12       -          2         9           14         -
  Wyo.                      1           -           2       -          1         2            5         -
  Colo.                   100           2         304       2          3         -           95         -
  N. Mex.                  13           -         138       -          1         -           85         -
  Ariz.                    46           8         415       -          -         -          319         5
  Utah                      4           -          50       -          3         -           48         -
  Nev.                     36           2         195       1          -         -          115         -

Pacific                   640         119       6,027       6         29         3        5,385        90
  Wash.                    17           2         212       -          1         -          278         4
  Oreg.                     5           -          67       -          -         -          156         4
  Calif.                  616         117       5,703       5         28         3        4,677        75
  Alaska                    2           -          20       -          -         -           81         -
  Hawaii                    -           -          25       1          -         -          193         7
  Guam                      -           -           6       1          -         -           NA         1
  P.R.                    285           3       1,608       -          -         -          263         3
  V.I.                      2           -          19       -          -         -            4         -
  C.N.M.I.                 NA          NA          NA       1          -         -           37        96
  American Samoa           NA          NA          NA      NA         NA        NA           NA        NA
-----------------------------------------------------------------------------------------------------------
* Cases were updated through the Division of Sexually Transmitted Diseases Prevention, NCHSTP,       NA: Not Available
  as of March 1, 1996.                                                                               NN: Not Notifiable
+ Cases were updated through the Division of Tuberculosis Elimination, NCHSTP, as of May 29, 1996.    -: No reported cases
============================================================================================================================

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