Skip Navigation LinksSkip Navigation Links
Centers for Disease Control and Prevention
Safer Healthier People
Blue White
Blue White
bottom curve
CDC Home Search Health Topics A-Z spacer spacer
spacer
Blue curve MMWR spacer
spacer
spacer

The content on this page is being archived for historic and reference purposes only. The content, links, and pdfs are no longer maintained and might be outdated.

Limited Availability of Penicillin G Sodium

On December 17, 1993, Marsam Pharmaceuticals * (Cherry Hill, New Jersey), the sole manufacturer of Penicillin G Sodium, reported that the supplier of the active ingredient ceased production. As a result, inventories of Penicillin G Sodium for Injection may become low or depleted. Penicillin G Sodium is generally used in patients who cannot tolerate Penicillin G Potassium (e.g., patients with renal impairment).

Most patients requiring parenteral penicillin therapy can tolerate Penicillin G Potassium, of which there is no shortage. Acceptable alternative therapy may be available for many patients with renal impairment; however, physicians should evaluate alternatives on a case-by-case basis.

Marsam Pharmaceuticals and the Food and Drug Administration have identified a new manufacturer of the active ingredient, and required testing is in progress. In the interim, Marsam Pharmaceuticals will retain an emergency supply of Penicillin G Sodium. Physicians who have patients for whom no substitute is acceptable should contact Marsam Pharmaceuticals, telephone (800) 883-2600.

Reported by: Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration.

  • Use of trade names and commercial sources is for identification only and does not imply endorsement by the Public Health Service or the U.S. Department of Health and Human Services.



Disclaimer   All MMWR HTML versions of articles are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the electronic PDF version and/or the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.

**Questions or messages regarding errors in formatting should be addressed to mmwrq@cdc.gov.

Page converted: 09/19/98

HOME  |  ABOUT MMWR  |  MMWR SEARCH  |  DOWNLOADS  |  RSSCONTACT
POLICY  |  DISCLAIMER  |  ACCESSIBILITY

Safer, Healthier People

Morbidity and Mortality Weekly Report
Centers for Disease Control and Prevention
1600 Clifton Rd, MailStop E-90, Atlanta, GA 30333, U.S.A

USA.GovDHHS

Department of Health
and Human Services

This page last reviewed 5/2/01