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Availability of the CDC/NIH Manual, Biosafety in Microbiological and Biomedical Laboratories

The second edition of Biosafety in the Microbiological and Biomedical Laboratories is now available.

This document was developed jointly by CDC and the National Institutes of Health in 1984 to help define the principles of biosafety and to provide guidelines for implementing them in the research laboratory. It outlines standard and special microbiologic practices, safety equipment, and facilities that constitute four biosafety levels. Recommended safe microbiologic techniques are described in detail for special infectious agents through the use of agent summary statements. The 1988 edition is identical in content but has added the Agent Summary Statement for Human Immunodeficiency Virus and Report on Laboratory-Acquired Infection with Human Immunodeficiency Virus (1) to the information in the first edition.

Requests from academic institutions and private laboratories for single copies should be directed to NIH/DS, 31-1C02, Bethesda, MD, 20892. Copies for other institutions or multiple copies may be obtained for $3.75 per copy (stock no. 107-040-000508-3) from the Superintendent of Documents, U.S. Government Printing Office, Washington, D.C., 20402.


  1. CDC. 1988 agent summary statement for human immunodeficiency virus and report on laboratory-acquired infection with human immunodeficiency virus. MMWR 1988;37(suppl S-4).

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