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Correction of Error Regarding Malaria Treatment in Disease-A-Month

In the March 1984 issue of Disease-A-Month, an article entitled, "Tropical Diseases of North America," appeared. In Table 5, "Malaria Prophylaxis and Therapy" on page 39, a potentially serious error of dosage appeared--the pediatric dose of primaquine phosphate was printed in error as 5 mg/kg/day x 14 days. This is 10 times the correct dose, which is 0.5 mg/kg/day (or 0.3 mg/kg/day of primaquine base) x 14 days. Since primaquine has a relatively low therapeutic index, the stated dose could lead to significant toxicity, and this correction should be noted. The stated maximum dose ("not to exceed 26.3 mg/day") is correct.

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