When Caring for Patients Under Investigation (PUIs) or Patients with Confirmed Ebola Virus Disease (EVD)

Think Ebola: Early recognition is critical for infection control:


Think Ebola when you approach a patient. Start the steps for basic infection control before assessing the patient for risks.

  • Always use standard precautions.
  • If there are concerns that the patient could meet the criteria for Ebola, immediately separate the patient from others.


Assess your patient for

  • International travel


  • Contact with someone with EVD.


  • Fever
  • Other symptoms are
    • Severe headache
    • Muscle pain
    • Weakness
    • Fatigue
    • Diarrhea
    • Vomiting
    • Abdominal (stomach) pain
    • Unexplained hemorrhage (bleeding or bruising)
  • If the patient has both exposure and symptoms, immediately separate the patient and inform others (see INFORM).


If assessment indicates possible Ebola virus infection, take action.

  • Isolate the patient in a private room with a private bathroom or covered, bedside commode and close the door.
  • Wear appropriate personal protective equipment (PPE).
  • Limit the healthcare personnel who enter the room.
  • Keep a log of everyone who enters and leaves the patient’s room.
  • Consider alternative diagnoses, and evaluate appropriately.
  • Perform only necessary tests and procedures.
  • Avoid aerosol-generating procedures.
  • Follow CDC guidelines for cleaning, disinfecting, and managing waste.


Alert others, including public health authorities.

  • Notify your facility’s infection control program and other appropriate staff.
  • Contact your state or local public health authorities.
  • Consult with state or local public health authorities about testing for EVD.
  • See list of state and local health department numbers.