The Immunization Gateway (IZ Gateway) is a cloud-based message routing service intended to enable data exchange among jurisdiction IIS, other provider systems, and the CDC Immunization Data Clearinghouse (IZ Data Clearinghouse). The IZ Gateway enables IISs, federal agencies, and private partners to connect and share immunization information. It also enables providers to update, query, and report immunization data to an IIS. By using centralized data exchange, it avoids the need for multiple, individual, point-to-point connections. Additional information for IIS awardees can be found on SharePointexternal icon.