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Yellow Fever

History, Epidemiology, and Vaccination Information


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Yellow Fever Vaccines


Things to Consider

Adverse Events

Monitoring Patients



Hypersensitivity Reactions

Infants younger than 6 months

Immunocompromising Conditions

Case: Immunosuppression

Thymus Disorder

Case: Thymus Disorder


Asymptomatic HIV Infection-1

Asymptomatic HIV Infection-2

Case: Asymptomatic HIV Infection


Case: Pregnancy


Case: Breastfeeding

Adults aged 60 years and older

Infants aged 6-8 months

Question 3

Question 4


A precaution is a condition in a vaccine recipient that might increase the risk for a serious adverse reaction or that might compromise the ability of the vaccine to produce immunity. According to the ACIP recommendations, vaccination should be deferred when a precaution is present. However, yellow fever vaccination can be considered in these situations if travel to an endemic area is unavoidable and the benefits of vaccination outweigh the risks. Note that the ACIP considers moderate to severe acute illness, with or without fever, as a precaution to administration of all vaccines.

Precautions to yellow fever vaccine administration are:

         Asymptomatic HIV infection with moderately decreased CD4+ counts



         Adults aged 60 years or older

         Infants aged 6–8 months

For specific guidance in these situations, follow the recommendations of the ACIP or contact your state health department. Vaccination recommendations also are available at 1-800-CDC-INFO.

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