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The most effective strategy to ensure adherence to treatment is directly observed therapy (DOT).  


With DOT, a patient meets with a health care worker every day or several times a week. The patient takes the TB medicines while the health care worker watches. The health care worker also asks the patient about any problems or side effects with the medication. DOT should be done at a time and place that is convenient for the patient.  


DOT should be used for ALL patients with TB disease, including children and adolescents. There is no way to accurately predict whether a patient will adhere to treatment without this assistance.

Directly observed therapy (DOT)